Colonización por Pneumocystis jirovecii en la enfermedad pulmonar obstructiva crónica.

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Title: Colonización por Pneumocystis jirovecii en la enfermedad pulmonar obstructiva crónica.
Alternate Title: Colonization by Pneumocystis jirovecii in Chronic Obstructive Pulmonary Disease.
Authors: Cañas A., Alejandra1 (AUTHOR) alejandra.canas@javeriana.edu.co, Garzón H., Javier R.2 (AUTHOR), Hernández F., Catalina3 (AUTHOR), Burbano G., Juan F.4 (AUTHOR), Cita P., José E.5 (AUTHOR), Parra G., Claudia M.6 (AUTHOR)
Source: Universitas Médica. 2018, Vol. 59 Issue 3, p1-10. 12p.
Abstract (English): Chronic obstructive pulmonary disease (COPD) is a prevalent disease in our population, which characteristically has a progressive deterioration and alters the quality of life of patients. Only 15-20% of patients with a history of smoking develop the disease, so there are additional environmental and genetic factors that influence the progression of the disease. Of the infectious causes that have taken importance is Pneumocystis jirovecii , this is a ubiquitous fungus that comes into contact with the airway of humans since childhood and is a cause of pneumonia in immunosuppressed patients. In addition, high rates of colonization have been reported in patients with COPD, which increase with the severity of the disease. COPD and P. jirovecii infection appear to share a similar immune response, which may explain the role of fungal colonization in the progression and severity of the disease. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): La enfermedad pulmonar obstructiva crónica (EPOC) es una enfermedad prevalente en la población colombiana, que característicamente tiene un deterioro progresivo y altera la calidad de vida de los pacientes. Solo del 15% al 20% de los pacientes con antecedente de tabaquismo desarrollan la enfermedad, por lo que factores ambientales y genéticos adicionales influyen en su progresión. De las causas infecciosas que han tomado importancia, el Pneumocystis jirovecii , un hongo ubicuo que entra en contacto con la vía aérea de los humanos desde la infancia, es causa de neumonía en pacientes inmunosuprimidos. Se han descrito tasas elevadas de colonización en pacientes con EPOC, que aumentan con la severidad de la enfermedad. EPOC e infección por P. jirovecii parecen compartir una respuesta inmunológica similar, lo cual podría explicar el papel de la colonización por el hongo en su progresión y gravedad. [ABSTRACT FROM AUTHOR]
Copyright of Universitas Médica is the property of Pontificia Universidad Javeriana and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Colonización por Pneumocystis jirovecii en la enfermedad pulmonar obstructiva crónica.
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  Data: Colonization by Pneumocystis jirovecii in Chronic Obstructive Pulmonary Disease.
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  Data: <searchLink fieldCode="AR" term="%22Cañas+A%2E%2C+Alejandra%22">Cañas A., Alejandra</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> alejandra.canas@javeriana.edu.co</i><br /><searchLink fieldCode="AR" term="%22Garzón+H%2E%2C+Javier+R%2E%22">Garzón H., Javier R.</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hernández+F%2E%2C+Catalina%22">Hernández F., Catalina</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Burbano+G%2E%2C+Juan+F%2E%22">Burbano G., Juan F.</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cita+P%2E%2C+José+E%2E%22">Cita P., José E.</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Parra+G%2E%2C+Claudia+M%2E%22">Parra G., Claudia M.</searchLink><relatesTo>6</relatesTo> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Universitas+Médica%22">Universitas Médica</searchLink>. 2018, Vol. 59 Issue 3, p1-10. 12p.
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Chronic obstructive pulmonary disease (COPD) is a prevalent disease in our population, which characteristically has a progressive deterioration and alters the quality of life of patients. Only 15-20% of patients with a history of smoking develop the disease, so there are additional environmental and genetic factors that influence the progression of the disease. Of the infectious causes that have taken importance is Pneumocystis jirovecii , this is a ubiquitous fungus that comes into contact with the airway of humans since childhood and is a cause of pneumonia in immunosuppressed patients. In addition, high rates of colonization have been reported in patients with COPD, which increase with the severity of the disease. COPD and P. jirovecii infection appear to share a similar immune response, which may explain the role of fungal colonization in the progression and severity of the disease. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: La enfermedad pulmonar obstructiva crónica (EPOC) es una enfermedad prevalente en la población colombiana, que característicamente tiene un deterioro progresivo y altera la calidad de vida de los pacientes. Solo del 15% al 20% de los pacientes con antecedente de tabaquismo desarrollan la enfermedad, por lo que factores ambientales y genéticos adicionales influyen en su progresión. De las causas infecciosas que han tomado importancia, el Pneumocystis jirovecii , un hongo ubicuo que entra en contacto con la vía aérea de los humanos desde la infancia, es causa de neumonía en pacientes inmunosuprimidos. Se han descrito tasas elevadas de colonización en pacientes con EPOC, que aumentan con la severidad de la enfermedad. EPOC e infección por P. jirovecii parecen compartir una respuesta inmunológica similar, lo cual podría explicar el papel de la colonización por el hongo en su progresión y gravedad. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Universitas Médica is the property of Pontificia Universidad Javeriana and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.11144/Javeriana.umed59-3.pneu
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              Text: 2018
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