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Human Papilloma Virus genotypes in Type III cervical intraepithelial neoplasia. Cuenca-Ecuador, 2013-2017.

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Title: Human Papilloma Virus genotypes in Type III cervical intraepithelial neoplasia. Cuenca-Ecuador, 2013-2017.
Alternate Title: Genotipos del virus del papiloma humano en neoplasias intraepiteliales tipo III; Cuenca-Ecuador, 2013-2017.
Authors: Patricio Santiago, Tigre-Sinchi1 psntiago_ts_befa@hotmail.com, Zoila Katherine, Salazar-Torres2 ambolivar@hotmail.com, Lizette, Espinosa-Martin3 lespinosam@ucacue.edu.ec, Karla Alexandra, Aspiazu-Hinostroza4 kaspiazuh@ucacue.edu.ec, Hermel Medardo, Espinosa3 hespinozae@ucacue.edu.ec, Freddy Rosendo, Cárdena-Heredia2 fcardenash@ucacue.edu.ec
Source: Revista Kasmera. jul-dec2019, Vol. 47 Issue 2, p95-101. 7p.
Abstract (English): Cervical cancer is one of the most common cancers in female population worldwide in underdeveloped countries, and in Ecuador it stands out in second place. This research focuses on HPV-genotype description in type III-intraepithelial neoplasms. The study type was analytical, retrospective and cross-sectional. The sample was 195 patients with NIC III diagnosis, from 20 to 60 years old, who were in the data system of "Sociedad de Lucha Contra el Cancer" Cuenca- Ecuador, 2013-2017 term. It was established that HPV-16 genotype was in 32.9% (n 51) of all cases; factors like sociodemographic variables, tobacco use, infection, hormonal contraceptives use, more than one sexual partner, age of start of active sex life equal or less than 20 years old, didn't show a relationship with HPV infection; on the other hand, IUD use and HPV-16 infection had a statically significant relationship (OR 2,75; CI 95% 1,21-6,26; p 0,01). HPV genotype HPV-16 was the most common, and IUD use was a risk factor to get HPV infection. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): El cáncer de cuello uterino, es uno de los cánceres más frecuentes en la población femenina a nivel mundial en países subdesarrollados, y en Ecuador ocupa el segundo lugar. Esta investigación se sitúa en la descripción de los genotipos del VPH en neoplasias intraepiteliales tipo III. El tipo de estudio fue analítico, retrospectivo y transversal. La muestra fueron 195 pacientes con diagnóstico de NIC III, de 20 hasta los 60 años de edad, que se encontraba en el sistema informático de la "Sociedad de Lucha Contra el Cáncer", Cuenca - Ecuador, periodo 2013 - 2017. Los datos fueron procesados a través del software SPSS 23.00. Se determinó que el genotipo VPH-16 estuvo en el 32,9% (n 51) de los casos; las variables sociodemográficas, consumo de tabaco, infecciones, uso de anticonceptivos hormonales, más de una pareja sexual, IVSA igual o menor de 20 años no presentaron relación a la infección por VPH; pero, el uso de DIU e infección por VPH-16 tuvo una relación estadísticamente significativa (OR 2,75; IC 95% 1,21-6,26; p 0,01). El genotipo de VPH-16 fue el más frecuente, y el uso de DIU fue un factor de riesgo para adquirir la infección por el VPH. [ABSTRACT FROM AUTHOR]
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Database: MedicLatina
Description
Abstract:Cervical cancer is one of the most common cancers in female population worldwide in underdeveloped countries, and in Ecuador it stands out in second place. This research focuses on HPV-genotype description in type III-intraepithelial neoplasms. The study type was analytical, retrospective and cross-sectional. The sample was 195 patients with NIC III diagnosis, from 20 to 60 years old, who were in the data system of "Sociedad de Lucha Contra el Cancer" Cuenca- Ecuador, 2013-2017 term. It was established that HPV-16 genotype was in 32.9% (n 51) of all cases; factors like sociodemographic variables, tobacco use, infection, hormonal contraceptives use, more than one sexual partner, age of start of active sex life equal or less than 20 years old, didn't show a relationship with HPV infection; on the other hand, IUD use and HPV-16 infection had a statically significant relationship (OR 2,75; CI 95% 1,21-6,26; p 0,01). HPV genotype HPV-16 was the most common, and IUD use was a risk factor to get HPV infection. [ABSTRACT FROM AUTHOR]
ISSN:00755222
DOI:10.5281/zenodo.3521760