Manejo de queloides mediante combinación de cirugía y radioterapia con haz de electrones.

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Bibliographic Details
Title:	Manejo de queloides mediante combinación de cirugía y radioterapia con haz de electrones.
Alternate Title:	Management of keloid through combination of surgery and radiotherapy with electron beam.
Authors:	CALDERÓN, Wilfredo¹, CAMACHO, Juan Pablo², OBAÍD, Miguel³, SUBIABRE, Rodrigo², VINÉS, Eugenio⁴
Source:	Cirugía Plástica Ibero-Latinoamericana. Ene-Mar2020, Vol. 46 Issue 1, p57-64. 8p.
Abstract (English):	Background and objective. Keloids cause deterioration in the quality of life of patients due to cosmetic disfigurement, pain and pruritus. Although there is a wide range of therapeutic options and even a combination of these, there are still high recurrence rates that make keloids treatment a challenge. We report our rate of recurrence of keloid in different body areas after surgery associated with radiotherapy electron beam in the immediate postoperative period using a defined radiotherapy protocol. Methods. An ambispective study was carried out in the Plastic Surgery Unit at Salvador Hospital and Santa María Clinic in Santiago (Chile) between 2010 and 2017, colleting patients operated on by keloids with surgery and protocolized treatment of electron radiation therapy. Patients who did not attend the radiotherapy treatment, it was performed after 24 hours, or they were not followed up for at least 3 months, were excluded. We evaluated demographic, clinical data, past history of frustrated procedures, keloid number and keloid recurrence. Chi-square statistical test was used using statistical significance p=0.05. Results. A total of 15 patients with 32 keloids in different body areas were treated, with an average follow-up time of 862 days. All patients underwent surgical and radiotherapy treatment without inconveniences and good tolerance. The average total recurrence was 34%, with the greatest recurrence in the dorsal area (83%) and with no recurrences in the auricular one. Conclusions. Excisional surgical treatment of keloids, followed by beam radiation therapy according to the protocol described, results in no recurrence in the auricular area. [ABSTRACT FROM AUTHOR]
Abstract (Spanish):	Introducción y objetivo. La formación de queloides condiciona un deterioro en la calidad de vida de los pacientes por causar desfiguración cosmética, dolor y prurito. A pesar de que existe una amplia gama de opciones terapéuticas e incluso combinación de estas, aun existen tasas de recurrencia elevadas que hacen del tratamiento de los queloides un desafío complejo. Recogemos nuestra tasa de recurrencia de queloides en diferentes áreas corporales tras cirugía asociada a radioterapia con haz de electrones en el postoperatorio inmediato mediante un protocolo de radioterapia definido. Material y método. Estudio de tipo ambispectivo en los centros de Cirugía Plástica del Hospital del Salvador y Clínica Santa María en Santiago (Chile) entre 2010 y 2017 sobre pacientes intervenidos por queloides mediante cirugía y tratamiento protocolizado con radioterapia de electrones. Excluimos pacientes que no asistieron al tratamiento con radioterapia, o se realizó después de 24 horas, o no se les realizó seguimiento durante al menos 3 meses. Evaluamos datos demográficos, clínicos, antecedentes de procedimientos anteriores frustrados, número de queloides y recurrencia. Utilizamos como prueba estadística chi-cuadrado con significancia estadística p=0.05. Resultados. Estudiamos un total de 15 pacientes con un total de 32 queloides intervenidos en distintas áreas corporales con seguimiento promedio de 862 días. En todos realizamos el procedimiento sin inconvenientes y con buena tolerancia. El promedio de recidiva total fue del 34%, siendo la zona de mayor recurrencia la dorsal (83%) y la de menor la auricular donde no hubo recidivas. Conclusiones. En nuestra experiencia, el tratamiento quirúrgico escisional de los queloides, seguido de radioterapia con haz de electrones según el protocolo expuesto, resultó sin recidivas en la zona auricular. [ABSTRACT FROM AUTHOR]
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Database:	MedicLatina

Description
Abstract:	Background and objective. Keloids cause deterioration in the quality of life of patients due to cosmetic disfigurement, pain and pruritus. Although there is a wide range of therapeutic options and even a combination of these, there are still high recurrence rates that make keloids treatment a challenge. We report our rate of recurrence of keloid in different body areas after surgery associated with radiotherapy electron beam in the immediate postoperative period using a defined radiotherapy protocol. Methods. An ambispective study was carried out in the Plastic Surgery Unit at Salvador Hospital and Santa María Clinic in Santiago (Chile) between 2010 and 2017, colleting patients operated on by keloids with surgery and protocolized treatment of electron radiation therapy. Patients who did not attend the radiotherapy treatment, it was performed after 24 hours, or they were not followed up for at least 3 months, were excluded. We evaluated demographic, clinical data, past history of frustrated procedures, keloid number and keloid recurrence. Chi-square statistical test was used using statistical significance p=0.05. Results. A total of 15 patients with 32 keloids in different body areas were treated, with an average follow-up time of 862 days. All patients underwent surgical and radiotherapy treatment without inconveniences and good tolerance. The average total recurrence was 34%, with the greatest recurrence in the dorsal area (83%) and with no recurrences in the auricular one. Conclusions. Excisional surgical treatment of keloids, followed by beam radiation therapy according to the protocol described, results in no recurrence in the auricular area. [ABSTRACT FROM AUTHOR]
ISSN:	03767892
DOI:	10.4321/S0376-78922020000100008