View in EDS PDF Full Text

Calidad de vida en mujeres con cáncer de mama sometidas a quimioterapia en Cali, Colombia.

Saved in:
Bibliographic Details
Title: Calidad de vida en mujeres con cáncer de mama sometidas a quimioterapia en Cali, Colombia.
Alternate Title: Quality of life in women treated with chemotherapy for breast cancer in Cali, Colombia.
Authors: Mejía-Rojas, María Elena1, Contreras-Rengifo, Adolfo2, Hernández-Carrillo, Mauricio3 mauriciohc@gmail.com
Source: Biomédica: Revista del Instituto Nacional de Salud. jun2020, Vol. 40 Issue 2, p349-361. 13p.
Subjects: CANCER chemotherapy, SEXUAL excitement, QUALITY of life, LOGISTIC regression analysis, BREAST cancer, HOT flashes
Geographic Terms: CALI (Colombia)
Abstract (English): Introduction: Breast cancer is a serious neoplasm that originates in mammary tissues whose treatment with chemotherapy seems to generate significant changes in the quality of life. Objective: To determine the risk factors associated with health-related quality of life in women with breast cancer under chemotherapy in Cali, Colombia. Materials and methods: We conducted an observational, cross-sectional study with analytical components in a sample of 80 female patients using the QLQ-C30 questionnaire for cancer, and the QLQ-BR23 for breast cancer, as well as sociodemographic and clinical information. We performed a logistic regression analysis to determine associated risk factors through adjusted OR and 95% CI; the quality of life was classified using the QLQ-BR23. Results: The most relevant symptoms were fatigue, insomnia, and hair loss. Physical functionality, feelings of pleasure, and sexual activity were reduced. The factors associated with low quality of life were mammary symptoms (adjusted OR= 5.5; 95% CI: 1.2-24.8; p = 0.038), systemic therapy side effects (adjusted OR = 7.3; IC95%: 2.6-22.1; p = 0.012), lower sexual pleasure (adjusted OR = 1.8; IC95%: 1.2-11.8; p = 0.027) and reduction of expectations about the future (adjusted OR = 4.2; IC95%: 1.1-17.8; p = 0.045). Conclusions: The quality of life in women with breast cancer and under chemotherapy was mainly affected by the side effects of the therapy; the most relevant signs and symptoms identified were hair loss, insomnia, and fatigue besides breast symptoms, lower physical functionality, and decreased sensation of sexual pleasure. We recommend intervention strategies aimed at improving the quality of life and the physical and emotional care of these patients. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción. El cáncer de mama es una neoplasia grave que se origina en los tejidos mamarios y cuyo tratamiento demanda quimioterapia, con los consecuentes cambios en la calidad de vida. Objetivo. Determinar los factores de riesgo asociados con la calidad de vida relacionada con la salud en mujeres con cáncer de mama sometidas a quimioterapia en Cali, Colombia. Materiales y métodos. Se hizo un estudio observacional y transversal con componente analítico en una muestra de 80 mujeres, utilizando los cuestionarios QLQ-C30 para cáncer y QLQ-BR23 para cáncer de mama, así como información sociodemográfica y clínica. Se hizo un análisis de regresión logística para determinar los factores asociados con las razones de momios (odd ratios, OR) ajustadas y un intervalo de confianza (IC) de 95 %; la calidad de vida se clasificó mediante el cuestionario QLQ-BR23. Resultados. Los síntomas más relevantes fueron fatiga, insomnio y pérdida de cabello. Se redujeron la funcionalidad física, las sensaciones de placer y la actividad sexual. Los factores asociados con la baja calidad de vida fueron los síntomas mamarios (OR ajustada=5,5; IC95% 1,2-24,8; p=0,038), los efectos secundarios del tratamiento sistémico (OR ajustada=7,3; IC95% 2,6-22,1; p=0,012), un menor placer sexual (OR ajustada=1,8; IC95% 1,2-11,8; p=0,027) y la reducción de expectativas para el futuro (OR ajustada=4,2; IC95% 1,1-17,8; p=0,045). Conclusiones. En las mujeres con cáncer de mama sometidas a quimioterapia, la calidad de vida se vio afectada principalmente por los efectos secundarios del tratamiento, en tanto que los signos y los síntomas más relevantes fueron la pérdida del cabello, el insomnio y la fatiga, además de los síntomas mamarios, la menor funcionalidad física y la menor sensación de placer sexual. Se recomienda la implementación de estrategias de intervención destinadas a mejorar la calidad de vida, y el cuidado físico y emocional de las pacientes. [ABSTRACT FROM AUTHOR]
Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: lth
DbLabel: MedicLatina
An: 144319234
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Calidad de vida en mujeres con cáncer de mama sometidas a quimioterapia en Cali, Colombia.
– Name: TitleAlt
  Label: Alternate Title
  Group: TiAlt
  Data: Quality of life in women treated with chemotherapy for breast cancer in Cali, Colombia.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Mejía-Rojas%2C+María+Elena%22">Mejía-Rojas, María Elena</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Contreras-Rengifo%2C+Adolfo%22">Contreras-Rengifo, Adolfo</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Hernández-Carrillo%2C+Mauricio%22">Hernández-Carrillo, Mauricio</searchLink><relatesTo>3</relatesTo><i> mauriciohc@gmail.com</i>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Biomédica%3A+Revista+del+Instituto+Nacional+de+Salud%22">Biomédica: Revista del Instituto Nacional de Salud</searchLink>. jun2020, Vol. 40 Issue 2, p349-361. 13p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22CANCER+chemotherapy%22">CANCER chemotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22SEXUAL+excitement%22">SEXUAL excitement</searchLink><br /><searchLink fieldCode="DE" term="%22QUALITY+of+life%22">QUALITY of life</searchLink><br /><searchLink fieldCode="DE" term="%22LOGISTIC+regression+analysis%22">LOGISTIC regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22BREAST+cancer%22">BREAST cancer</searchLink><br /><searchLink fieldCode="DE" term="%22HOT+flashes%22">HOT flashes</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22CALI+%28Colombia%29%22">CALI (Colombia)</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Introduction: Breast cancer is a serious neoplasm that originates in mammary tissues whose treatment with chemotherapy seems to generate significant changes in the quality of life. Objective: To determine the risk factors associated with health-related quality of life in women with breast cancer under chemotherapy in Cali, Colombia. Materials and methods: We conducted an observational, cross-sectional study with analytical components in a sample of 80 female patients using the QLQ-C30 questionnaire for cancer, and the QLQ-BR23 for breast cancer, as well as sociodemographic and clinical information. We performed a logistic regression analysis to determine associated risk factors through adjusted OR and 95% CI; the quality of life was classified using the QLQ-BR23. Results: The most relevant symptoms were fatigue, insomnia, and hair loss. Physical functionality, feelings of pleasure, and sexual activity were reduced. The factors associated with low quality of life were mammary symptoms (adjusted OR= 5.5; 95% CI: 1.2-24.8; p = 0.038), systemic therapy side effects (adjusted OR = 7.3; IC95%: 2.6-22.1; p = 0.012), lower sexual pleasure (adjusted OR = 1.8; IC95%: 1.2-11.8; p = 0.027) and reduction of expectations about the future (adjusted OR = 4.2; IC95%: 1.1-17.8; p = 0.045). Conclusions: The quality of life in women with breast cancer and under chemotherapy was mainly affected by the side effects of the therapy; the most relevant signs and symptoms identified were hair loss, insomnia, and fatigue besides breast symptoms, lower physical functionality, and decreased sensation of sexual pleasure. We recommend intervention strategies aimed at improving the quality of life and the physical and emotional care of these patients. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Introducción. El cáncer de mama es una neoplasia grave que se origina en los tejidos mamarios y cuyo tratamiento demanda quimioterapia, con los consecuentes cambios en la calidad de vida. Objetivo. Determinar los factores de riesgo asociados con la calidad de vida relacionada con la salud en mujeres con cáncer de mama sometidas a quimioterapia en Cali, Colombia. Materiales y métodos. Se hizo un estudio observacional y transversal con componente analítico en una muestra de 80 mujeres, utilizando los cuestionarios QLQ-C30 para cáncer y QLQ-BR23 para cáncer de mama, así como información sociodemográfica y clínica. Se hizo un análisis de regresión logística para determinar los factores asociados con las razones de momios (odd ratios, OR) ajustadas y un intervalo de confianza (IC) de 95 %; la calidad de vida se clasificó mediante el cuestionario QLQ-BR23. Resultados. Los síntomas más relevantes fueron fatiga, insomnio y pérdida de cabello. Se redujeron la funcionalidad física, las sensaciones de placer y la actividad sexual. Los factores asociados con la baja calidad de vida fueron los síntomas mamarios (OR ajustada=5,5; IC95% 1,2-24,8; p=0,038), los efectos secundarios del tratamiento sistémico (OR ajustada=7,3; IC95% 2,6-22,1; p=0,012), un menor placer sexual (OR ajustada=1,8; IC95% 1,2-11,8; p=0,027) y la reducción de expectativas para el futuro (OR ajustada=4,2; IC95% 1,1-17,8; p=0,045). Conclusiones. En las mujeres con cáncer de mama sometidas a quimioterapia, la calidad de vida se vio afectada principalmente por los efectos secundarios del tratamiento, en tanto que los signos y los síntomas más relevantes fueron la pérdida del cabello, el insomnio y la fatiga, además de los síntomas mamarios, la menor funcionalidad física y la menor sensación de placer sexual. Se recomienda la implementación de estrategias de intervención destinadas a mejorar la calidad de vida, y el cuidado físico y emocional de las pacientes. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=144319234
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.7705/biomedica.4971
    Languages:
      – Code: spa
        Text: Spanish
    PhysicalDescription:
      Pagination:
        PageCount: 13
        StartPage: 349
    Subjects:
      – SubjectFull: CANCER chemotherapy
        Type: general
      – SubjectFull: SEXUAL excitement
        Type: general
      – SubjectFull: QUALITY of life
        Type: general
      – SubjectFull: LOGISTIC regression analysis
        Type: general
      – SubjectFull: BREAST cancer
        Type: general
      – SubjectFull: HOT flashes
        Type: general
      – SubjectFull: CALI (Colombia)
        Type: general
    Titles:
      – TitleFull: Calidad de vida en mujeres con cáncer de mama sometidas a quimioterapia en Cali, Colombia.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Mejía-Rojas, María Elena
      – PersonEntity:
          Name:
            NameFull: Contreras-Rengifo, Adolfo
      – PersonEntity:
          Name:
            NameFull: Hernández-Carrillo, Mauricio
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: jun2020
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-print
              Value: 01204157
          Numbering:
            – Type: volume
              Value: 40
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Biomédica: Revista del Instituto Nacional de Salud
              Type: main
ResultId 1