View in EDS PDF Full Text

Twins from different fathers: A heteropaternal superfecundation case report in Colombia.

Saved in:
Bibliographic Details
Title: Twins from different fathers: A heteropaternal superfecundation case report in Colombia.
Alternate Title: Gemelos de diferentes padres: un caso de superfecundación heteropaternal en Colombia.
Authors: Mogollón, Fernanda1, Casas-Vargas, Andrea1, Rodríguez, Fredy1, Usaquén, William1 wusaquenm@unal.edu.co
Source: Biomédica: Revista del Instituto Nacional de Salud. dic2020, Vol. 40 Issue 4, p604-608. 5p.
Subjects: UNIVERSIDAD Nacional de Colombia, MICROSATELLITE repeats, TWINS, BIRTHFATHERS, FETOFETAL transfusion, SEXUAL intercourse, GENETIC markers
Geographic Terms: COLOMBIA
Abstract (English): Heteropaternal superfecundation is an extremely rare phenomenon that occurs when a second ova released during the same menstrual cycle is additionally fertilized by the sperm cells of a different man in separate sexual intercourse. In August, 2018, the Grupo de Genética de Poblaciones e Identificación at Universidad Nacional de Colombia received a request to establish the paternity of a pair of male twins with genetic markers. The following analyses were performed: amelogenin gene, autosomal short tandem repeat (STR), and Y-STR analyses by means of human identification commercial kits, paternity index, and the probability of paternity calculation and interpretation. A paternity index of 2.5134E+7 and a probability of paternity of 99.9999% for twin 2 were obtained while 14 out of 17 Y-chromosome markers and 14 out of 21 autosomal short tandem repeats were excluded for twin 1. The results indicated that the twins have different biological fathers. Although heteropaternal superfecundation is rarely observed among humans given its low frequency, in paternity disputes for dizygotic twins it is mandatory to demand the presence of the two twins in the testing to avoid wrong conclusions. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): La superfecundación heteropaternal es un fenómeno extremadamente raro que se produce cuando un segundo óvulo, liberado durante el mismo ciclo menstrual, es fertilizado por un espermatozoide de un hombre diferente en relaciones sexuales separadas. En agosto de 2018, el Grupo de Genética de Poblaciones e Identificación de la Universidad Nacional de Colombia recibió una solicitud para establecer la paternidad mediante marcadores genéticos de un par de mellizos varones, en quienes se hizo el análisis del gen de amelogenina, el análisis de repeticiones cortas en tándem (Short Tandem Repeats, STR) autosómicas y del cromosoma Y (Y-STR) mediante kits comerciales de identificación humana y cálculos e interpretación del índice de paternidad y probabilidad de paternidad. Se obtuvo un índice de paternidad de 2,5134E+7 y una probabilidad de paternidad de 99,9999% para el gemelo 2, en tanto que en el gemelo 1 se excluyeron 14 de los 17 marcadores del cromosoma Y y 14 de los 21 sistemas STR autosómicos evaluados. Los resultados indicaron que los gemelos tienen diferentes padres biológicos. A pesar de que la superfecundación heteropaternal rara vez se observa en humanos debido a su baja frecuencia, en las disputas de paternidad para los gemelos dicigóticos, es obligatorio exigir en la prueba la presencia de los dos gemelos para evitar conclusiones incorrectas. [ABSTRACT FROM AUTHOR]
Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: lth
DbLabel: MedicLatina
An: 147666351
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Twins from different fathers: A heteropaternal superfecundation case report in Colombia.
– Name: TitleAlt
  Label: Alternate Title
  Group: TiAlt
  Data: Gemelos de diferentes padres: un caso de superfecundación heteropaternal en Colombia.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Mogollón%2C+Fernanda%22">Mogollón, Fernanda</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Casas-Vargas%2C+Andrea%22">Casas-Vargas, Andrea</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rodríguez%2C+Fredy%22">Rodríguez, Fredy</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Usaquén%2C+William%22">Usaquén, William</searchLink><relatesTo>1</relatesTo><i> wusaquenm@unal.edu.co</i>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Biomédica%3A+Revista+del+Instituto+Nacional+de+Salud%22">Biomédica: Revista del Instituto Nacional de Salud</searchLink>. dic2020, Vol. 40 Issue 4, p604-608. 5p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22UNIVERSIDAD+Nacional+de+Colombia%22">UNIVERSIDAD Nacional de Colombia</searchLink><br /><searchLink fieldCode="DE" term="%22MICROSATELLITE+repeats%22">MICROSATELLITE repeats</searchLink><br /><searchLink fieldCode="DE" term="%22TWINS%22">TWINS</searchLink><br /><searchLink fieldCode="DE" term="%22BIRTHFATHERS%22">BIRTHFATHERS</searchLink><br /><searchLink fieldCode="DE" term="%22FETOFETAL+transfusion%22">FETOFETAL transfusion</searchLink><br /><searchLink fieldCode="DE" term="%22SEXUAL+intercourse%22">SEXUAL intercourse</searchLink><br /><searchLink fieldCode="DE" term="%22GENETIC+markers%22">GENETIC markers</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22COLOMBIA%22">COLOMBIA</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Heteropaternal superfecundation is an extremely rare phenomenon that occurs when a second ova released during the same menstrual cycle is additionally fertilized by the sperm cells of a different man in separate sexual intercourse. In August, 2018, the Grupo de Genética de Poblaciones e Identificación at Universidad Nacional de Colombia received a request to establish the paternity of a pair of male twins with genetic markers. The following analyses were performed: amelogenin gene, autosomal short tandem repeat (STR), and Y-STR analyses by means of human identification commercial kits, paternity index, and the probability of paternity calculation and interpretation. A paternity index of 2.5134E+7 and a probability of paternity of 99.9999% for twin 2 were obtained while 14 out of 17 Y-chromosome markers and 14 out of 21 autosomal short tandem repeats were excluded for twin 1. The results indicated that the twins have different biological fathers. Although heteropaternal superfecundation is rarely observed among humans given its low frequency, in paternity disputes for dizygotic twins it is mandatory to demand the presence of the two twins in the testing to avoid wrong conclusions. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: La superfecundación heteropaternal es un fenómeno extremadamente raro que se produce cuando un segundo óvulo, liberado durante el mismo ciclo menstrual, es fertilizado por un espermatozoide de un hombre diferente en relaciones sexuales separadas. En agosto de 2018, el Grupo de Genética de Poblaciones e Identificación de la Universidad Nacional de Colombia recibió una solicitud para establecer la paternidad mediante marcadores genéticos de un par de mellizos varones, en quienes se hizo el análisis del gen de amelogenina, el análisis de repeticiones cortas en tándem (Short Tandem Repeats, STR) autosómicas y del cromosoma Y (Y-STR) mediante kits comerciales de identificación humana y cálculos e interpretación del índice de paternidad y probabilidad de paternidad. Se obtuvo un índice de paternidad de 2,5134E+7 y una probabilidad de paternidad de 99,9999% para el gemelo 2, en tanto que en el gemelo 1 se excluyeron 14 de los 17 marcadores del cromosoma Y y 14 de los 21 sistemas STR autosómicos evaluados. Los resultados indicaron que los gemelos tienen diferentes padres biológicos. A pesar de que la superfecundación heteropaternal rara vez se observa en humanos debido a su baja frecuencia, en las disputas de paternidad para los gemelos dicigóticos, es obligatorio exigir en la prueba la presencia de los dos gemelos para evitar conclusiones incorrectas. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=147666351
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.7705/biomedica.5100
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 5
        StartPage: 604
    Subjects:
      – SubjectFull: UNIVERSIDAD Nacional de Colombia
        Type: general
      – SubjectFull: MICROSATELLITE repeats
        Type: general
      – SubjectFull: TWINS
        Type: general
      – SubjectFull: BIRTHFATHERS
        Type: general
      – SubjectFull: FETOFETAL transfusion
        Type: general
      – SubjectFull: SEXUAL intercourse
        Type: general
      – SubjectFull: GENETIC markers
        Type: general
      – SubjectFull: COLOMBIA
        Type: general
    Titles:
      – TitleFull: Twins from different fathers: A heteropaternal superfecundation case report in Colombia.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Mogollón, Fernanda
      – PersonEntity:
          Name:
            NameFull: Casas-Vargas, Andrea
      – PersonEntity:
          Name:
            NameFull: Rodríguez, Fredy
      – PersonEntity:
          Name:
            NameFull: Usaquén, William
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 12
              Text: dic2020
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-print
              Value: 01204157
          Numbering:
            – Type: volume
              Value: 40
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Biomédica: Revista del Instituto Nacional de Salud
              Type: main
ResultId 1