The role of neutrophil-lymphocyte ratio in patients with chronic obstructive pulmonary disease in Babylon province.

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Title: The role of neutrophil-lymphocyte ratio in patients with chronic obstructive pulmonary disease in Babylon province.
Alternate Title: El papel de la relación neutrófilos-linfocitos en pacientes con enfermedad pulmonar obstructiva crónica en la provincia de Babilonia.
Authors: Jasim, Ahmed Hussein1 med.ahmed.hus@uobabylon.edu.iq
Source: Revista Latinoamericana de Hipertensión. 2021, Vol. 16 Issue 3, p192-195. 4p.
Subjects: CHRONIC obstructive pulmonary disease, LYMPHOCYTE count, NEUTROPHIL lymphocyte ratio, COVID-19, INTENSIVE care units, DISEASE exacerbation
Geographic Terms: IRAQ
Abstract (English): Introduction: Chronic obstructive pulmonary disease (COPD) is a complex illness, associated with many comorbidities, it is usually misdiagnosed and underrated, the aim of study is to regulate whether neutrophil lymphocyte ratio (NLR) can be used in diagnosis of COPD. Method: Comparative cross sectional study, the data was conducted between 1 December 2019 and 1 March 2020 among patients with approved diagnosis of AECOPD and attendees to emergency unit and respiratory outpatient clinic or admitted to general word and intensive care unit. The attendees to emergency unit and respiratory outpatient clinic or admitted to general word and intensive care unit were asked to participate in this study and sample size of 79 patients were included in this study. Other 79 healthy persons they attended emergency unit as relative to patients were selected as the control group. Results: Comparative cross sectional study of 79 patients with COPD and 79 patients normal, mean ± SD of age (66 ±10) years old and N/L ratio (5.9 ± 4.8), according to fig (1); (45.57%) of patients with COPD have sever FEV1 and (30.38%) of patients have moderate FEV1. In addition, fig (2) show 73% of patients in current study are males and 27% are females with 71% are old age (more than 60 years old). There is significant difference between NLR of patients with COPD and normal patients, increase in NLR occur in patients with COPD. Conclusion: NLR may beneficial inflammation predictor in diagnosis COPD and its acute exacerbation. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción: La Enfermedad Pulmonar Obstructiva Crónica (EPOC) es una enfermedad compleja, asociada a muchas comorbilidades, usualmente es mal diagnosticada y subestimada, el objetivo del estudio es regular si el cociente de linfocitos neutrófilos (NLR) se puede utilizar en el diagnóstico de la EPOC. Método: Estudio transversal comparativo, los datos se realizaron entre el 1 de diciembre de 2019 y el 1 de marzo de 2020 entre pacientes con diagnóstico aprobado de AECOPD y asistentes a unidad de urgencias y ambulatorio respiratorio o ingresados en unidad general de palabra y cuidados intensivos. Se solicitó la participación en este estudio a los asistentes a la unidad de urgencias y al ambulatorio respiratorio o ingresados en la unidad de cuidados intensivos y de palabra general y se incluyó en este estudio un tamaño de muestra de 79 pacientes. Otras 79 personas sanas atendidas en la unidad de urgencias en relación con los pacientes fueron seleccionadas como grupo de control. Resultados: Estudio transversal comparativo de 79 pacientes con EPOC y 79 pacientes normales, media ± DE de edad (66±10) años y relación N / L (5,9±4,8), según figura 1; (45,57%) de los pacientes con EPOC tienen un FEV1 severo y (30,38%) de los pacientes tienen un FEV1 moderado. Además, la figura 2 muestra que el 73% de los pacientes en el estudio actual son hombres y el 27% son mujeres y el 71% son ancianos (más de 60 años). Existe una diferencia significativa entre el NLR de los pacientes con EPOC y los pacientes normales, el aumento del NLR se produce en los pacientes con EPOC. Conclusión: la NLR puede ser un predictor de inflamación beneficioso en el diagnóstico de EPOC y su exacerbación aguda. [ABSTRACT FROM AUTHOR]
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Database: MedicLatina
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Abstract:Introduction: Chronic obstructive pulmonary disease (COPD) is a complex illness, associated with many comorbidities, it is usually misdiagnosed and underrated, the aim of study is to regulate whether neutrophil lymphocyte ratio (NLR) can be used in diagnosis of COPD. Method: Comparative cross sectional study, the data was conducted between 1 December 2019 and 1 March 2020 among patients with approved diagnosis of AECOPD and attendees to emergency unit and respiratory outpatient clinic or admitted to general word and intensive care unit. The attendees to emergency unit and respiratory outpatient clinic or admitted to general word and intensive care unit were asked to participate in this study and sample size of 79 patients were included in this study. Other 79 healthy persons they attended emergency unit as relative to patients were selected as the control group. Results: Comparative cross sectional study of 79 patients with COPD and 79 patients normal, mean ± SD of age (66 ±10) years old and N/L ratio (5.9 ± 4.8), according to fig (1); (45.57%) of patients with COPD have sever FEV1 and (30.38%) of patients have moderate FEV1. In addition, fig (2) show 73% of patients in current study are males and 27% are females with 71% are old age (more than 60 years old). There is significant difference between NLR of patients with COPD and normal patients, increase in NLR occur in patients with COPD. Conclusion: NLR may beneficial inflammation predictor in diagnosis COPD and its acute exacerbation. [ABSTRACT FROM AUTHOR]
ISSN:18564550
DOI:10.5281/zenodo.5651253