Decalogue for the selection of oral antibiotics for lower respiratory tract infections.
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| Title: | Decalogue for the selection of oral antibiotics for lower respiratory tract infections. |
|---|---|
| Alternate Title: | Decálogo para la selección del antibiótico oral en las infecciones respiratorias de vías bajas. |
| Authors: | Cantón, Rafael1,2 rafael.canton@salud.madrid.org, Barberán, José3, Linares, Manuel4, María Molero, José5, Miguel Rodríguez-González-Moro, José6, Salavert, Miguel7, González del Castillo, Juan8 jgonzalezcast@gmail.com |
| Source: | Revista Española de Quimioterapia. Feb2022, Vol. 35 Issue 1, p16-29. 14p. |
| Subjects: | RESPIRATORY infections, ANTIBIOTICS, DRUG resistance in microorganisms, ANTI-infective agents, DRUG side effects |
| Abstract (English): | Lower respiratory tract infections, including chronic obstructive pulmonary disease exacerbations (COPD-E) and community acquired pneumonia (CAP), are one of the most frequent reasons for consultation in primary care and hospital emergency departments, and are the cause of a high prescription of antimicrobial agents. The selection of the most appropriate oral antibiotic treatment is based on different aspects and includes to first consider a bacterial aetiology and not a viral infection, to know the bacterial pathogen that most frequently cause these infections and the frequency of their local antimicrobial resistance. Treatment should also be prescribed quickly and antibiotics should be selected among those with a quicker mode of action, achieving the greatest effect in the shortest time and with the fewest adverse effects (toxicity, interactions, resistance and/or ecological impact). Whenever possible, antimicrobials should be rotated and diversified and switched to the oral route as soon as possible. With these premises, the oral treatment guidelines for mild or moderate COPD-E and CAP in Spain include as first options betalactam antibiotics (amoxicillin and amoxicillin-clavulanate and cefditoren), in certain situations associated with a macrolide, and relegating fluoroquinolones as an alternative, except in cases where the presence of Pseudomonas aeruginosa is suspected. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Las infecciones del tracto respiratorio inferior, incluyendo las exacerbaciones de la enfermedad pulmonar obstructiva crónica (EPOC) y la neumonía adquirida en la comunidad (NAC), son uno de los motivos de consulta más frecuentes en atención primaria y los servicios de urgencias hospitalarios, y son la causa de una elevada prescripción de antimicrobianos. La selección del tratamiento oral más adecuado con antibióticos se basa en diferentes aspectos e incluye considerar en primer lugar una etiología bacteriana y no una infección vírica, conocer los patógenos bacterianos que más frecuentemente causa estas infecciones y la frecuencia local de su resistencia antimicrobiana. Además, el tratamiento debe prescribirse rápidamente y los antibióticos deben seleccionarse entre los que tienen un modo de acción más rápido, logrando el mayor efecto en el menor tiempo y con el menor número de efectos adversos (toxicidad, interacciones, resistencia y/o impacto ecológico). Siempre que sea posible, hay que rotar y diversificar los antimicrobianos y pasar a la vía oral lo antes posible. Con estas premisas, las guías de tratamiento oral de la exacerbación leve o moderada de la EPOC y NAC en España incluyen como primera opción los antibióticos betalactámicos (amoxicilina y amoxicilina-clavulánico y cefditoreno), en determinadas situaciones asociados a un macrólido, y relegando las fluoroquinolonas como alternativa, salvo en los casos en que se sospeche la presencia de Pseudomonas aeruginosa. [ABSTRACT FROM AUTHOR] |
| Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
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| Header | DbId: lth DbLabel: MedicLatina An: 154784326 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Decalogue for the selection of oral antibiotics for lower respiratory tract infections. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Decálogo para la selección del antibiótico oral en las infecciones respiratorias de vías bajas. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Cantón%2C+Rafael%22">Cantón, Rafael</searchLink><relatesTo>1,2</relatesTo><i> rafael.canton@salud.madrid.org</i><br /><searchLink fieldCode="AR" term="%22Barberán%2C+José%22">Barberán, José</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Linares%2C+Manuel%22">Linares, Manuel</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22María+Molero%2C+José%22">María Molero, José</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Miguel+Rodríguez-González-Moro%2C+José%22">Miguel Rodríguez-González-Moro, José</searchLink><relatesTo>6</relatesTo><br /><searchLink fieldCode="AR" term="%22Salavert%2C+Miguel%22">Salavert, Miguel</searchLink><relatesTo>7</relatesTo><br /><searchLink fieldCode="AR" term="%22González+del+Castillo%2C+Juan%22">González del Castillo, Juan</searchLink><relatesTo>8</relatesTo><i> jgonzalezcast@gmail.com</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Revista+Española+de+Quimioterapia%22">Revista Española de Quimioterapia</searchLink>. Feb2022, Vol. 35 Issue 1, p16-29. 14p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22RESPIRATORY+infections%22">RESPIRATORY infections</searchLink><br /><searchLink fieldCode="DE" term="%22ANTIBIOTICS%22">ANTIBIOTICS</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+resistance+in+microorganisms%22">DRUG resistance in microorganisms</searchLink><br /><searchLink fieldCode="DE" term="%22ANTI-infective+agents%22">ANTI-infective agents</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+side+effects%22">DRUG side effects</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Lower respiratory tract infections, including chronic obstructive pulmonary disease exacerbations (COPD-E) and community acquired pneumonia (CAP), are one of the most frequent reasons for consultation in primary care and hospital emergency departments, and are the cause of a high prescription of antimicrobial agents. The selection of the most appropriate oral antibiotic treatment is based on different aspects and includes to first consider a bacterial aetiology and not a viral infection, to know the bacterial pathogen that most frequently cause these infections and the frequency of their local antimicrobial resistance. Treatment should also be prescribed quickly and antibiotics should be selected among those with a quicker mode of action, achieving the greatest effect in the shortest time and with the fewest adverse effects (toxicity, interactions, resistance and/or ecological impact). Whenever possible, antimicrobials should be rotated and diversified and switched to the oral route as soon as possible. With these premises, the oral treatment guidelines for mild or moderate COPD-E and CAP in Spain include as first options betalactam antibiotics (amoxicillin and amoxicillin-clavulanate and cefditoren), in certain situations associated with a macrolide, and relegating fluoroquinolones as an alternative, except in cases where the presence of Pseudomonas aeruginosa is suspected. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Las infecciones del tracto respiratorio inferior, incluyendo las exacerbaciones de la enfermedad pulmonar obstructiva crónica (EPOC) y la neumonía adquirida en la comunidad (NAC), son uno de los motivos de consulta más frecuentes en atención primaria y los servicios de urgencias hospitalarios, y son la causa de una elevada prescripción de antimicrobianos. La selección del tratamiento oral más adecuado con antibióticos se basa en diferentes aspectos e incluye considerar en primer lugar una etiología bacteriana y no una infección vírica, conocer los patógenos bacterianos que más frecuentemente causa estas infecciones y la frecuencia local de su resistencia antimicrobiana. Además, el tratamiento debe prescribirse rápidamente y los antibióticos deben seleccionarse entre los que tienen un modo de acción más rápido, logrando el mayor efecto en el menor tiempo y con el menor número de efectos adversos (toxicidad, interacciones, resistencia y/o impacto ecológico). Siempre que sea posible, hay que rotar y diversificar los antimicrobianos y pasar a la vía oral lo antes posible. Con estas premisas, las guías de tratamiento oral de la exacerbación leve o moderada de la EPOC y NAC en España incluyen como primera opción los antibióticos betalactámicos (amoxicilina y amoxicilina-clavulánico y cefditoreno), en determinadas situaciones asociados a un macrólido, y relegando las fluoroquinolonas como alternativa, salvo en los casos en que se sospeche la presencia de Pseudomonas aeruginosa. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.37201/req/172.2021 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 14 StartPage: 16 Subjects: – SubjectFull: RESPIRATORY infections Type: general – SubjectFull: ANTIBIOTICS Type: general – SubjectFull: DRUG resistance in microorganisms Type: general – SubjectFull: ANTI-infective agents Type: general – SubjectFull: DRUG side effects Type: general Titles: – TitleFull: Decalogue for the selection of oral antibiotics for lower respiratory tract infections. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cantón, Rafael – PersonEntity: Name: NameFull: Barberán, José – PersonEntity: Name: NameFull: Linares, Manuel – PersonEntity: Name: NameFull: María Molero, José – PersonEntity: Name: NameFull: Miguel Rodríguez-González-Moro, José – PersonEntity: Name: NameFull: Salavert, Miguel – PersonEntity: Name: NameFull: González del Castillo, Juan IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb2022 Type: published Y: 2022 Identifiers: – Type: issn-print Value: 02143429 Numbering: – Type: volume Value: 35 – Type: issue Value: 1 Titles: – TitleFull: Revista Española de Quimioterapia Type: main |
| ResultId | 1 |
