DIAGNOSTIC YIELD OF COMPUTED TOMOGRAPHY GUIDED FINE-NEEDLE ASPIRATION FOR PANCREATIC CANCER.

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Title: DIAGNOSTIC YIELD OF COMPUTED TOMOGRAPHY GUIDED FINE-NEEDLE ASPIRATION FOR PANCREATIC CANCER.
Alternate Title: Rendimiento diagnóstico de la aspiración con aguja fina guiada por tomografía computarizada para el cáncer de páncreas.
Authors: TCHERCANSKY, ARIEL1, FERNANDEZ ALBERTI, JOAQUÍN1, ARRECHEA ANTELO, RAMIRO1 arrechea_94@hotmail.com, BREGANTE, MARIANO L.1, PIRCHI, DANIEL E.1
Source: Medicina (Buenos Aires). sep/oct2022, Vol. 82 Issue 5, p708-713. 6p.
Subjects: NEEDLE biopsy, PANCREATIC cancer, ENDOSCOPIC surgery, COMPUTED tomography, ADENOCARCINOMA, NEOPLASTIC cell transformation
Abstract (English): Fine-needle aspiration (FNA) for the histological diagnosis of occupying lesions in the pancreas as opposed to tru-cut needle biopsy to obtain tissue for analysis has been associated with a lower incidence of post-procedure complications, with almost immediate recovery and no need for hospital stay. Nevertheless, the question of the diagnostic effectiveness of percutaneous computed axial tomography (CT)-guided FNA in solid pancreatic lesions has been raised. The aim of this study was to confirm the diagnostic effectivity of percutaneous CT-guided FNA in pancreatic space-occupying lesions and to assess short-term complications. All percutaneous CT-guided FNA with real-time monitoring, performed between April 2010 and December 2015, were retrospectively analyzed. In all cases 21-gauge needles were used. All FNA were performed in the presence of a pathologist who immediately stained and reported as adequate for analysis in all cases. The diagnosis was confirmed by histopathological evaluation. Of 54 FNA performed, final histopathological evaluation revealed neoplastic cells compatible with adenocarcinoma in 52 patients (96%) and was negative for neoplastic cells in two patients (4%). The sensitivity was 94%, and the specificity 100%. Post-FNA morbidity was observed in four patients, consisting of epigastric pain in two and abdominal wall hematoma in two other patients. Percutaneous CT-guided FNA of pancreatic space-occupying lesions was found to be a good, minimally invasive and safe method with low morbidity. The presence of the pathologist in the procedure allowed for immediate cytological diagnosis. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): El uso de la punción-aspiración con aguja fina (PAAF) en el diagnóstico histológico de lesiones ocupantes de páncreas es una alternativa frente al uso de agujas tru-cut en la obtención de tejido para su análisis, con una incidencia más baja de complicaciones y una recuperación casi inmediata sin necesidad de internación. El objetivo fue valorar la efectividad diagnóstica de las PAAF de lesiones ocupantes pancreáticas guiadas por tomografía axial computada (TAC) por vía percutánea, y su tasa de complicaciones a corto plazo. Se analizaron de forma retrospectiva todas las PAAF realizadas mediante guía tomográfica por vía percutánea con control en tiempo real, entre abril 2010 y diciembre 2015. Todas las PAAF se realizaron en presencia de un patólogo que inmediatamente tiñó e informó como adecuado para el análisis. La confirmación diagnóstica se hizo con el análisis anatomopatológico diferido. De las 54 PAAF realizadas, el diagnóstico anatomopatológico informó positivo para células neoplásicas compatible con adenocarcinoma en 52 pacientes (96%) y en otros dos (4%) como negativo para células neoplásicas. La sensibilidad del método fue 94% y la especificidad del 100%. Se registraron 4 casos de morbilidad post punción (2 dolores epigástricos y 2 hematomas de pared abdominal). Las punciones percutáneas de lesiones ocupantes pancreáticas guiadas por TC pueden considerarse un buen método diagnóstico mini invasivo, seguro, con una morbilidad post punción baja. La presencia del patólogo en el procedimiento permitió el diagnóstico citológico inmediato. [ABSTRACT FROM AUTHOR]
Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: DIAGNOSTIC YIELD OF COMPUTED TOMOGRAPHY GUIDED FINE-NEEDLE ASPIRATION FOR PANCREATIC CANCER.
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  Label: Alternate Title
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  Data: Rendimiento diagnóstico de la aspiración con aguja fina guiada por tomografía computarizada para el cáncer de páncreas.
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  Data: <searchLink fieldCode="JN" term="%22Medicina+%28Buenos+Aires%29%22">Medicina (Buenos Aires)</searchLink>. sep/oct2022, Vol. 82 Issue 5, p708-713. 6p.
– Name: Subject
  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22NEEDLE+biopsy%22">NEEDLE biopsy</searchLink><br /><searchLink fieldCode="DE" term="%22PANCREATIC+cancer%22">PANCREATIC cancer</searchLink><br /><searchLink fieldCode="DE" term="%22ENDOSCOPIC+surgery%22">ENDOSCOPIC surgery</searchLink><br /><searchLink fieldCode="DE" term="%22COMPUTED+tomography%22">COMPUTED tomography</searchLink><br /><searchLink fieldCode="DE" term="%22ADENOCARCINOMA%22">ADENOCARCINOMA</searchLink><br /><searchLink fieldCode="DE" term="%22NEOPLASTIC+cell+transformation%22">NEOPLASTIC cell transformation</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Fine-needle aspiration (FNA) for the histological diagnosis of occupying lesions in the pancreas as opposed to tru-cut needle biopsy to obtain tissue for analysis has been associated with a lower incidence of post-procedure complications, with almost immediate recovery and no need for hospital stay. Nevertheless, the question of the diagnostic effectiveness of percutaneous computed axial tomography (CT)-guided FNA in solid pancreatic lesions has been raised. The aim of this study was to confirm the diagnostic effectivity of percutaneous CT-guided FNA in pancreatic space-occupying lesions and to assess short-term complications. All percutaneous CT-guided FNA with real-time monitoring, performed between April 2010 and December 2015, were retrospectively analyzed. In all cases 21-gauge needles were used. All FNA were performed in the presence of a pathologist who immediately stained and reported as adequate for analysis in all cases. The diagnosis was confirmed by histopathological evaluation. Of 54 FNA performed, final histopathological evaluation revealed neoplastic cells compatible with adenocarcinoma in 52 patients (96%) and was negative for neoplastic cells in two patients (4%). The sensitivity was 94%, and the specificity 100%. Post-FNA morbidity was observed in four patients, consisting of epigastric pain in two and abdominal wall hematoma in two other patients. Percutaneous CT-guided FNA of pancreatic space-occupying lesions was found to be a good, minimally invasive and safe method with low morbidity. The presence of the pathologist in the procedure allowed for immediate cytological diagnosis. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: El uso de la punción-aspiración con aguja fina (PAAF) en el diagnóstico histológico de lesiones ocupantes de páncreas es una alternativa frente al uso de agujas tru-cut en la obtención de tejido para su análisis, con una incidencia más baja de complicaciones y una recuperación casi inmediata sin necesidad de internación. El objetivo fue valorar la efectividad diagnóstica de las PAAF de lesiones ocupantes pancreáticas guiadas por tomografía axial computada (TAC) por vía percutánea, y su tasa de complicaciones a corto plazo. Se analizaron de forma retrospectiva todas las PAAF realizadas mediante guía tomográfica por vía percutánea con control en tiempo real, entre abril 2010 y diciembre 2015. Todas las PAAF se realizaron en presencia de un patólogo que inmediatamente tiñó e informó como adecuado para el análisis. La confirmación diagnóstica se hizo con el análisis anatomopatológico diferido. De las 54 PAAF realizadas, el diagnóstico anatomopatológico informó positivo para células neoplásicas compatible con adenocarcinoma en 52 pacientes (96%) y en otros dos (4%) como negativo para células neoplásicas. La sensibilidad del método fue 94% y la especificidad del 100%. Se registraron 4 casos de morbilidad post punción (2 dolores epigástricos y 2 hematomas de pared abdominal). Las punciones percutáneas de lesiones ocupantes pancreáticas guiadas por TC pueden considerarse un buen método diagnóstico mini invasivo, seguro, con una morbilidad post punción baja. La presencia del patólogo en el procedimiento permitió el diagnóstico citológico inmediato. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Languages:
      – Code: eng
        Text: English
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        PageCount: 6
        StartPage: 708
    Subjects:
      – SubjectFull: NEEDLE biopsy
        Type: general
      – SubjectFull: PANCREATIC cancer
        Type: general
      – SubjectFull: ENDOSCOPIC surgery
        Type: general
      – SubjectFull: COMPUTED tomography
        Type: general
      – SubjectFull: ADENOCARCINOMA
        Type: general
      – SubjectFull: NEOPLASTIC cell transformation
        Type: general
    Titles:
      – TitleFull: DIAGNOSTIC YIELD OF COMPUTED TOMOGRAPHY GUIDED FINE-NEEDLE ASPIRATION FOR PANCREATIC CANCER.
        Type: main
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            NameFull: TCHERCANSKY, ARIEL
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            NameFull: FERNANDEZ ALBERTI, JOAQUÍN
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            NameFull: ARRECHEA ANTELO, RAMIRO
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            NameFull: BREGANTE, MARIANO L.
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            NameFull: PIRCHI, DANIEL E.
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              M: 09
              Text: sep/oct2022
              Type: published
              Y: 2022
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