PROGRAMA DE PREVENCIÓN DE ENTEROBACTERIAS PRODUCTORAS DE CARBAPENEMASAS EN UNIDADES CRÍTICAS EN ARGENTINA DURANTE LA PANDEMIA COVID-19.
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| Title: | PROGRAMA DE PREVENCIÓN DE ENTEROBACTERIAS PRODUCTORAS DE CARBAPENEMASAS EN UNIDADES CRÍTICAS EN ARGENTINA DURANTE LA PANDEMIA COVID-19. |
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| Alternate Title: | Program for the prevention of Carbapenemase-Producing Enterobacteria in critical units in Argentina during the COVID-19 pandemic. |
| Authors: | STANELONI, MARÍA INÉS1 maria.staneloni@hospitalitaliano.org.ar, ALONSO, LAURA1, ILARI, SILVIA1, HERRERA, MARÍA PAULA2, LÓPEZ, CARLOTA3, COLQUE, ÁNGEL4 |
| Source: | Medicina (Buenos Aires). sep/oct2022, Vol. 82 Issue 5, p722-731. 10p. |
| Abstract (English): | Introduction: The problem of carbapenemase-producing Enterobacteriaceae (CPE) was exacerbated by the COVID-19 pandemic in countries with a previous high incidence, such as Argentina. This study describes the development and results of a CPE prevention program, mainly carbapenemase-producing Klebsiellas (KPC), in three critical units of two public hospitals during 6 months of the pandemic. Methods: The objective was to reduce the incidence of KPC in clinical and colonization samples. This quasi-experimental study was based on a cycle of improvement and implementation of three measures: hand hygiene, environmental hygiene, and periodic surveillance with rectal swabs. Results: Regarding the measures, all the units optimized active surveillance, and two of these also improved hand and environmental hygiene. Comparing the pre- and post-intervention periods in the three units, no significant change was observed in the rate of KPC positive clinical samples. KPC colonization was significantly reduced in two units (unit 2: 51.6-18.5 p 0.0004, unit 3: 62.5-5.2 p < 0.0000001). All units showed a downtrend in both rates towards the end of the study. Conclusion: Containing or reducing the advance of the KPC in our region is possible even in difficult scenarios such as the pandemic. More studies are needed in low- and middle-income countries to demonstrate the impact of KPC prevention programs in these situations. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Introducción: La problemática de las enterobacterias productoras de carbapenemasas (EPC) se exacerbó con la pandemia por COVID-19 en países con una incidencia previa elevada, como la Argentina. Este estudio describe el desarrollo y resultados de un programa de prevención de EPC, fundamentalmente Klebsiellas productoras de carbapenemasas (KPC), en tres unidades críticas de dos hospitales públicos durante 6 meses de la pandemia. Métodos: El objetivo fue reducir la incidencia de KPC en muestras clínicas y de colonización. Este estudio, quasi experimental, se basó en un ciclo de mejora e implementación de tres medidas: higiene de manos, higiene ambiental y vigilancia periódica con hisopados rectales. Resultados: Respecto a las medidas, todas las unidades mejoraron la vigilancia activa y dos de estas tuvieron además mejoría en la higiene de manos e higiene ambiental. Comparando los períodos pre y post intervención en las tres unidades no se observaron cambios significativos en la tasa de muestras clínicas KPC positivas. Se logró disminuir en forma significativa la colonización por KPC en dos unidades (unidad 2: 51.6-18.5 p 0.0004, unidad 3: 62.5-5.2 p < 0.0000001). Todas las unidades mostraron hacia el final del estudio una tendencia al descenso en ambas tasas. Conclusión: Contener o reducir el avance de KPC en nuestra región es posible incluso en escenarios difíciles como el de la pandemia. Se necesitan más estudios en países de ingresos bajos y medianos, para demostrar el impacto de los programas de prevención de KPC en estas situaciones. [ABSTRACT FROM AUTHOR] |
| Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
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| Header | DbId: lth DbLabel: MedicLatina An: 159682207 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: PROGRAMA DE PREVENCIÓN DE ENTEROBACTERIAS PRODUCTORAS DE CARBAPENEMASAS EN UNIDADES CRÍTICAS EN ARGENTINA DURANTE LA PANDEMIA COVID-19. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Program for the prevention of Carbapenemase-Producing Enterobacteria in critical units in Argentina during the COVID-19 pandemic. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22STANELONI%2C+MARÍA+INÉS%22">STANELONI, MARÍA INÉS</searchLink><relatesTo>1</relatesTo><i> maria.staneloni@hospitalitaliano.org.ar</i><br /><searchLink fieldCode="AR" term="%22ALONSO%2C+LAURA%22">ALONSO, LAURA</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22ILARI%2C+SILVIA%22">ILARI, SILVIA</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22HERRERA%2C+MARÍA+PAULA%22">HERRERA, MARÍA PAULA</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22LÓPEZ%2C+CARLOTA%22">LÓPEZ, CARLOTA</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22COLQUE%2C+ÁNGEL%22">COLQUE, ÁNGEL</searchLink><relatesTo>4</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Medicina+%28Buenos+Aires%29%22">Medicina (Buenos Aires)</searchLink>. sep/oct2022, Vol. 82 Issue 5, p722-731. 10p. – Name: Abstract Label: Abstract (English) Group: Ab Data: Introduction: The problem of carbapenemase-producing Enterobacteriaceae (CPE) was exacerbated by the COVID-19 pandemic in countries with a previous high incidence, such as Argentina. This study describes the development and results of a CPE prevention program, mainly carbapenemase-producing Klebsiellas (KPC), in three critical units of two public hospitals during 6 months of the pandemic. Methods: The objective was to reduce the incidence of KPC in clinical and colonization samples. This quasi-experimental study was based on a cycle of improvement and implementation of three measures: hand hygiene, environmental hygiene, and periodic surveillance with rectal swabs. Results: Regarding the measures, all the units optimized active surveillance, and two of these also improved hand and environmental hygiene. Comparing the pre- and post-intervention periods in the three units, no significant change was observed in the rate of KPC positive clinical samples. KPC colonization was significantly reduced in two units (unit 2: 51.6-18.5 p 0.0004, unit 3: 62.5-5.2 p < 0.0000001). All units showed a downtrend in both rates towards the end of the study. Conclusion: Containing or reducing the advance of the KPC in our region is possible even in difficult scenarios such as the pandemic. More studies are needed in low- and middle-income countries to demonstrate the impact of KPC prevention programs in these situations. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Introducción: La problemática de las enterobacterias productoras de carbapenemasas (EPC) se exacerbó con la pandemia por COVID-19 en países con una incidencia previa elevada, como la Argentina. Este estudio describe el desarrollo y resultados de un programa de prevención de EPC, fundamentalmente Klebsiellas productoras de carbapenemasas (KPC), en tres unidades críticas de dos hospitales públicos durante 6 meses de la pandemia. Métodos: El objetivo fue reducir la incidencia de KPC en muestras clínicas y de colonización. Este estudio, quasi experimental, se basó en un ciclo de mejora e implementación de tres medidas: higiene de manos, higiene ambiental y vigilancia periódica con hisopados rectales. Resultados: Respecto a las medidas, todas las unidades mejoraron la vigilancia activa y dos de estas tuvieron además mejoría en la higiene de manos e higiene ambiental. Comparando los períodos pre y post intervención en las tres unidades no se observaron cambios significativos en la tasa de muestras clínicas KPC positivas. Se logró disminuir en forma significativa la colonización por KPC en dos unidades (unidad 2: 51.6-18.5 p 0.0004, unidad 3: 62.5-5.2 p < 0.0000001). Todas las unidades mostraron hacia el final del estudio una tendencia al descenso en ambas tasas. Conclusión: Contener o reducir el avance de KPC en nuestra región es posible incluso en escenarios difíciles como el de la pandemia. Se necesitan más estudios en países de ingresos bajos y medianos, para demostrar el impacto de los programas de prevención de KPC en estas situaciones. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 10 StartPage: 722 Titles: – TitleFull: PROGRAMA DE PREVENCIÓN DE ENTEROBACTERIAS PRODUCTORAS DE CARBAPENEMASAS EN UNIDADES CRÍTICAS EN ARGENTINA DURANTE LA PANDEMIA COVID-19. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: STANELONI, MARÍA INÉS – PersonEntity: Name: NameFull: ALONSO, LAURA – PersonEntity: Name: NameFull: ILARI, SILVIA – PersonEntity: Name: NameFull: HERRERA, MARÍA PAULA – PersonEntity: Name: NameFull: LÓPEZ, CARLOTA – PersonEntity: Name: NameFull: COLQUE, ÁNGEL IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: sep/oct2022 Type: published Y: 2022 Identifiers: – Type: issn-print Value: 00257680 Numbering: – Type: volume Value: 82 – Type: issue Value: 5 Titles: – TitleFull: Medicina (Buenos Aires) Type: main |
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