Características clínico-epidemiológicas de sepsis neonatal temprana en un hospital público, Lima, Perú.
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| Title: | Características clínico-epidemiológicas de sepsis neonatal temprana en un hospital público, Lima, Perú. |
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| Alternate Title: | Clinical-epidemiological characteristics of early-onset neonatal sepsis in a public hospital, Lima, Peru. |
| Authors: | Ruiz B., Alessandra1 rospe2005@yahoo.es, Pantoja-Sánchez, Lilian R.1,2 |
| Source: | Revista Horizonte Médico. oct-dic2022, Vol. 22 Issue 4, p1-9. 9p. |
| Abstract (English): | Objective: To determine the clinical-epidemiological characteristics of newborns with early-onset neonatal sepsis in a public hospital in Lima, Peru, 2016-2017. Materials and methods: An observational, retrospective study of 303 newborns born in Hospital Nacional Dos de Mayo, diagnosed with early-onset neonatal sepsis (2016-2017) and with complete medical records. Maternal variables: age, education, marital status, prenatal care, PROM, type of delivery, UTI, chorioamnionitis, anemia; neonatal variables: sex, gestational age, weight, Apgar, clinical signs, hemoculture, isolated organism, treatment, antibiotic sensitivity. Data processed in Excel and analyzed in SPSS Statistics V25. The incidence of early-onset neonatal sepsis was determined. Results: Incidence of early-onset neonatal sepsis: 67.08/1,000 (2016) and 127.85/1,000 (2017) live births. Incidence of confirmed early-onset neonatal sepsis: 2.98 (2016) and 4.7 (2017). Out of all mothers, 45 % received no adequate prenatal checkup or no checkups; 25 % presented anemia, UTI, history of abortion. Newborns had tachypnea (52.80 %), tachycardia (17.50 %), hypotonia (18.20 %), fever (9.20 %). The therapy included ampicillin-amikacin for probable (86.54 %) and confirmed (85 %) sepsis. Germs, mostly gram positive, were isolated from 8.4 % of the newborns. Coagulase-negative Staphylococcus was the most common bacteria, resistant to clindamycin, oxacillin, ampicillin, cefotaxime, gentamicin, and sensitive to linezolid, vancomycin. Burkholderia gladioli was the only identified gramnegative organism, sensitive to levofloxacin, ciprofloxacin, ceftriaxone but resistant to gentamicin, amikacin. Conclusions: The clinical presentation of neonatal sepsis included tachypnea, tachycardia, hypotonia and fever. Grampositive bacteria were the most commonly isolated species, prevailing coagulase-negative Staphylococci. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Objetivo: Determinar características clínico-epidemiológicas de neonatos con sepsis neonatal temprana en hospital público, Lima-Perú, 2016-2017. Materiales y métodos: Estudio observacional, retrospectivo. Se consideró todos los neonatos nacidos vivos en el Hospital Nacional Dos de Mayo diagnosticados con sepsis neonatal temprana el 2016-2017, excepto historias clínicas incompletas, totalizando 303. Se estudiaron variables maternas (edad, educación, estado civil, control prenatal, RPM, tipo de parto, infección urinaria, corioamnionitis, anemia) y neonatales (sexo, edad gestacional, peso, Apgar 1/5 minutos, clínica, hemocultivo, agente aislado, tratamiento y sensibilidad antibiótica). El programa Excel se usó para el procesamiento de datos; SPSSv25 para el análisis descriptivo. Se calculó incidencia de sepsis neonatal temprana. Resultados: Incidencia de sepsis neonatal temprana en 67,08/1000 nacidos vivos en el 2016 y 12,785 en el 2017, la cual fue confirmada en 2,98 (2016) y 4,7 (2017). 45 % de madres sin control prenatal adecuado o sin controles; la cuarta parte presentó anemia, infección urinaria, antecedente de aborto. Clínica de neonatos: taquipnea (52,80 %), taquicardia (17,50 %), hipotonía (18,20 %), fiebre (9,20 %); tratamiento ampicilina-amikacina en sepsis probable (86,54 %) y sepsis confirmada (85 %). Se aisló gérmenes en 8,40 % de casos, mayoría Gram positivos; Staphylococcus coagulasa-negativa, el más frecuente, resistente a clindamicina, oxacilina, ampicilina, cefotaxima, gentamicina y sensible a linezolid, vancomicina. Burkholderia gladioli, única bacteria Gram negativa encontrada, sensible a levofloxacino, ciprofloxacino, ceftriaxona, pero resistente a gentamicina y amikacina. Conclusiones: Clínica de sepsis neonatal temprana caracterizada por taquipnea, taquicardia, hipotonía y fiebre. Bacterias Gram positivas las más aisladas; predominó Staphylococcus coagulasa-negativa. [ABSTRACT FROM AUTHOR] |
| Copyright of Revista Horizonte Médico is the property of Universidad de San Martin de Porres and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
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| Items | – Name: Title Label: Title Group: Ti Data: Características clínico-epidemiológicas de sepsis neonatal temprana en un hospital público, Lima, Perú. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Clinical-epidemiological characteristics of early-onset neonatal sepsis in a public hospital, Lima, Peru. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Ruiz+B%2E%2C+Alessandra%22">Ruiz B., Alessandra</searchLink><relatesTo>1</relatesTo><i> rospe2005@yahoo.es</i><br /><searchLink fieldCode="AR" term="%22Pantoja-Sánchez%2C+Lilian+R%2E%22">Pantoja-Sánchez, Lilian R.</searchLink><relatesTo>1,2</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Revista+Horizonte+Médico%22">Revista Horizonte Médico</searchLink>. oct-dic2022, Vol. 22 Issue 4, p1-9. 9p. – Name: Abstract Label: Abstract (English) Group: Ab Data: Objective: To determine the clinical-epidemiological characteristics of newborns with early-onset neonatal sepsis in a public hospital in Lima, Peru, 2016-2017. Materials and methods: An observational, retrospective study of 303 newborns born in Hospital Nacional Dos de Mayo, diagnosed with early-onset neonatal sepsis (2016-2017) and with complete medical records. Maternal variables: age, education, marital status, prenatal care, PROM, type of delivery, UTI, chorioamnionitis, anemia; neonatal variables: sex, gestational age, weight, Apgar, clinical signs, hemoculture, isolated organism, treatment, antibiotic sensitivity. Data processed in Excel and analyzed in SPSS Statistics V25. The incidence of early-onset neonatal sepsis was determined. Results: Incidence of early-onset neonatal sepsis: 67.08/1,000 (2016) and 127.85/1,000 (2017) live births. Incidence of confirmed early-onset neonatal sepsis: 2.98 (2016) and 4.7 (2017). Out of all mothers, 45 % received no adequate prenatal checkup or no checkups; 25 % presented anemia, UTI, history of abortion. Newborns had tachypnea (52.80 %), tachycardia (17.50 %), hypotonia (18.20 %), fever (9.20 %). The therapy included ampicillin-amikacin for probable (86.54 %) and confirmed (85 %) sepsis. Germs, mostly gram positive, were isolated from 8.4 % of the newborns. Coagulase-negative Staphylococcus was the most common bacteria, resistant to clindamycin, oxacillin, ampicillin, cefotaxime, gentamicin, and sensitive to linezolid, vancomycin. Burkholderia gladioli was the only identified gramnegative organism, sensitive to levofloxacin, ciprofloxacin, ceftriaxone but resistant to gentamicin, amikacin. Conclusions: The clinical presentation of neonatal sepsis included tachypnea, tachycardia, hypotonia and fever. Grampositive bacteria were the most commonly isolated species, prevailing coagulase-negative Staphylococci. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Objetivo: Determinar características clínico-epidemiológicas de neonatos con sepsis neonatal temprana en hospital público, Lima-Perú, 2016-2017. Materiales y métodos: Estudio observacional, retrospectivo. Se consideró todos los neonatos nacidos vivos en el Hospital Nacional Dos de Mayo diagnosticados con sepsis neonatal temprana el 2016-2017, excepto historias clínicas incompletas, totalizando 303. Se estudiaron variables maternas (edad, educación, estado civil, control prenatal, RPM, tipo de parto, infección urinaria, corioamnionitis, anemia) y neonatales (sexo, edad gestacional, peso, Apgar 1/5 minutos, clínica, hemocultivo, agente aislado, tratamiento y sensibilidad antibiótica). El programa Excel se usó para el procesamiento de datos; SPSSv25 para el análisis descriptivo. Se calculó incidencia de sepsis neonatal temprana. Resultados: Incidencia de sepsis neonatal temprana en 67,08/1000 nacidos vivos en el 2016 y 12,785 en el 2017, la cual fue confirmada en 2,98 (2016) y 4,7 (2017). 45 % de madres sin control prenatal adecuado o sin controles; la cuarta parte presentó anemia, infección urinaria, antecedente de aborto. Clínica de neonatos: taquipnea (52,80 %), taquicardia (17,50 %), hipotonía (18,20 %), fiebre (9,20 %); tratamiento ampicilina-amikacina en sepsis probable (86,54 %) y sepsis confirmada (85 %). Se aisló gérmenes en 8,40 % de casos, mayoría Gram positivos; Staphylococcus coagulasa-negativa, el más frecuente, resistente a clindamicina, oxacilina, ampicilina, cefotaxima, gentamicina y sensible a linezolid, vancomicina. Burkholderia gladioli, única bacteria Gram negativa encontrada, sensible a levofloxacino, ciprofloxacino, ceftriaxona, pero resistente a gentamicina y amikacina. Conclusiones: Clínica de sepsis neonatal temprana caracterizada por taquipnea, taquicardia, hipotonía y fiebre. Bacterias Gram positivas las más aisladas; predominó Staphylococcus coagulasa-negativa. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Revista Horizonte Médico is the property of Universidad de San Martin de Porres and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.24265/horizmed.2022.v22n4.07 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 9 StartPage: 1 Titles: – TitleFull: Características clínico-epidemiológicas de sepsis neonatal temprana en un hospital público, Lima, Perú. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ruiz B., Alessandra – PersonEntity: Name: NameFull: Pantoja-Sánchez, Lilian R. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: oct-dic2022 Type: published Y: 2022 Identifiers: – Type: issn-print Value: 1727558X Numbering: – Type: volume Value: 22 – Type: issue Value: 4 Titles: – TitleFull: Revista Horizonte Médico Type: main |
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