Ultrasound tenosynovitis: A differential feature of patients with seronegative rheumatoid arthritis.

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Bibliographic Details
Title: Ultrasound tenosynovitis: A differential feature of patients with seronegative rheumatoid arthritis.
Authors: Ruta, Santiago1 (AUTHOR) santiagoruta@gmail.com, Sanchez Prado, Einer1 (AUTHOR), Salvatori, Facundo1 (AUTHOR), Arguello, Juan1 (AUTHOR), Aguerre, Darío2 (AUTHOR), Magri, Sebastián1 (AUTHOR), García Salinas, Rodrigo1 (AUTHOR)
Source: Reumatología Clínica. Feb2023, Vol. 19 Issue 2, p63-66. 4p.
Subjects: TENOSYNOVITIS, RHEUMATOID arthritis, ULTRASONIC imaging, RHEUMATOID factor
Abstract (English): To identify differential features between patients with seropositive and seronegative rheumatoid arthritis (RA). Prospective cohort study, including patients who were admitted for polyarthralgia. At baseline was performed: laboratory studies, X -rays of hands and feet, ultrasound of both hands with power Doppler technique, clinical data and clinimetry. In subsequent visits the definitive diagnosis of RA was established or not. It was considered as seronegative RA when patients were negative for both RF and ACPAs. 746 patients were included, of which 128 (17.1%) ended with a final diagnosis of RA. Of these 128 patients, 87 (67.9%) were seropositive RA, while 41 (32%) were seronegative RA. The only feature that showed significant differences was the presence of tenosynovitis detected by ultrasound with a positive power Doppler signal, 13.7% of the patients with seropositive RA vs 41.6% of the patients with seronegative RA (p = 0.0028). The only differential feature of patients with seronegative RA was the higher proportion of tenosynovitis detected by ultrasound. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Identificar características diferenciales entre pacientes con artritis reumatoide (AR) seropositivos y seronegativos. Estudio de cohorte prospectivo, incluyendo pacientes con poliartralgias. Al inicio se realizó: estudios de laboratorio, radiografías de manos y pies, ecografía de ambas manos con técnica power doppler, datos clínicos y clinimetría. En visitas posteriores se estableció o no el diagnóstico definitivo de AR. Se consideró AR seronegativa cuando los pacientes eran negativos tanto para factor reumatoide como para anticuerpos antipéptido cíclico citrulinado. Se incluyeron 746 pacientes, de los cuales 128 (17,1%) terminaron con diagnóstico final de AR. De estos 128 pacientes, 87 (67,9%) eran AR seropositivos, mientras que 41 (32%) eran AR seronegativos. La única característica que mostró diferencias significativas fue la presencia de tenosinovitis detectada por ecografía con señal power doppler positiva, el 13,7% de los pacientes con AR seropositiva frente al 41,6% de los pacientes con AR seronegativa (p = 0,0028). El único rasgo diferencial de los pacientes con AR seronegativa fue la mayor proporción de tenosinovitis detectadas por ecografía. [ABSTRACT FROM AUTHOR]
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Abstract:To identify differential features between patients with seropositive and seronegative rheumatoid arthritis (RA). Prospective cohort study, including patients who were admitted for polyarthralgia. At baseline was performed: laboratory studies, X -rays of hands and feet, ultrasound of both hands with power Doppler technique, clinical data and clinimetry. In subsequent visits the definitive diagnosis of RA was established or not. It was considered as seronegative RA when patients were negative for both RF and ACPAs. 746 patients were included, of which 128 (17.1%) ended with a final diagnosis of RA. Of these 128 patients, 87 (67.9%) were seropositive RA, while 41 (32%) were seronegative RA. The only feature that showed significant differences was the presence of tenosynovitis detected by ultrasound with a positive power Doppler signal, 13.7% of the patients with seropositive RA vs 41.6% of the patients with seronegative RA (p = 0.0028). The only differential feature of patients with seronegative RA was the higher proportion of tenosynovitis detected by ultrasound. [ABSTRACT FROM AUTHOR]
ISSN:1699258X
DOI:10.1016/j.reuma.2022.04.003