Hipertensión arterial y deterioro neurocognitivo: una relación bidireccional.
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| Title: | Hipertensión arterial y deterioro neurocognitivo: una relación bidireccional. |
|---|---|
| Alternate Title: | Hypertension and neurocognitive impairment: A bidirectional relationship. |
| Authors: | Sánchez Montero, Génesis1 gene_sanchezm@hotmail.com, Gallo Valverde, Jean Carlos1, Logroño Bautista, Paola1, Quinteros Romero, Cesar1, Vázquez Verdugo, María1, Sinchi Chuqui, Carlos1, Cevallos Segovia, Pamela1, Garzón Quezada, Karina1 |
| Source: | Síndrome Cardiometabólico. 2021, Vol. 11 Issue 1, p34-38. 5p. |
| Abstract (English): | Nowadays, a relationship between hypertension (HT) and impairments in cognitive function has been recognized, especially when the former presents in middle age followed by hypotension at an older age. This relationship has been attributed to structural and functional changes in the brain vasculature, chiefly due to a proinflammatory state and oxidative stress, which are typical of HT, along with alterations of the blood-brain barrier and brain blood flow. Because HT is a modifiable risk factor, it has been thought that its opportune treatment may be a potential target for the prevention or delay of the development of cognitive disorders related to age. Although there are currently some studies substantiating this theory, more research is necessary. Therefore, the objective of this article is to describe the known pathophysiological mechanisms linking HT to neurocognitive impairment, and to summarize current evidence on the effectivity of antihypertensive agents for the prevention or delay of cognitive impairment. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Hoy en día se reconoce que existe una relación entre la hipertensión arterial (HTA) y el deterioro de la función cognitiva, especialmente cuando la HTA se presenta en la mediana edad seguida de hipotensión arterial en la edad tardía. Dicha relación ha sido atribuida a cambios estructurales y funcionales de la vasculatura cerebral, principalmente debido al estado proinflamatorio y estrés oxidativo característicos de la HTA, además de alteraciones de la permeabilidad de la barrera hematoencefálica y el flujo sanguíneo cerebral. Gracias a que la HTA es un factor de riesgo modificable, se ha planteado entonces la interrogante de si su tratamiento oportuno podría ser un potencial mecanismo para la prevención o retraso del desarrollo de los trastornos cognitivos relacionados a la edad y aunque actualmente existen estudios que respalden dicha teoría, han de ser necesarios un mayor número de estudios al respecto. Es por ello que el objetivo de la presente investigación es describir los mecanismos fisiopatológicos conocidos hasta el momento que relacionan la HTA con el deterioro de la función cognitiva, y resumir la evidencia actual sobre la efectividad de los agentes antihipertensivos para la prevención o el retraso del deterioro cognitivo. [ABSTRACT FROM AUTHOR] |
| Copyright of Síndrome Cardiometabólico is the property of Sindrome Cardiometabolico and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 161781859 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Hipertensión arterial y deterioro neurocognitivo: una relación bidireccional. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Hypertension and neurocognitive impairment: A bidirectional relationship. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sánchez+Montero%2C+Génesis%22">Sánchez Montero, Génesis</searchLink><relatesTo>1</relatesTo><i> gene_sanchezm@hotmail.com</i><br /><searchLink fieldCode="AR" term="%22Gallo+Valverde%2C+Jean+Carlos%22">Gallo Valverde, Jean Carlos</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Logroño+Bautista%2C+Paola%22">Logroño Bautista, Paola</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Quinteros+Romero%2C+Cesar%22">Quinteros Romero, Cesar</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Vázquez+Verdugo%2C+María%22">Vázquez Verdugo, María</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Sinchi+Chuqui%2C+Carlos%22">Sinchi Chuqui, Carlos</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Cevallos+Segovia%2C+Pamela%22">Cevallos Segovia, Pamela</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Garzón+Quezada%2C+Karina%22">Garzón Quezada, Karina</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Síndrome+Cardiometabólico%22">Síndrome Cardiometabólico</searchLink>. 2021, Vol. 11 Issue 1, p34-38. 5p. – Name: Abstract Label: Abstract (English) Group: Ab Data: Nowadays, a relationship between hypertension (HT) and impairments in cognitive function has been recognized, especially when the former presents in middle age followed by hypotension at an older age. This relationship has been attributed to structural and functional changes in the brain vasculature, chiefly due to a proinflammatory state and oxidative stress, which are typical of HT, along with alterations of the blood-brain barrier and brain blood flow. Because HT is a modifiable risk factor, it has been thought that its opportune treatment may be a potential target for the prevention or delay of the development of cognitive disorders related to age. Although there are currently some studies substantiating this theory, more research is necessary. Therefore, the objective of this article is to describe the known pathophysiological mechanisms linking HT to neurocognitive impairment, and to summarize current evidence on the effectivity of antihypertensive agents for the prevention or delay of cognitive impairment. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Hoy en día se reconoce que existe una relación entre la hipertensión arterial (HTA) y el deterioro de la función cognitiva, especialmente cuando la HTA se presenta en la mediana edad seguida de hipotensión arterial en la edad tardía. Dicha relación ha sido atribuida a cambios estructurales y funcionales de la vasculatura cerebral, principalmente debido al estado proinflamatorio y estrés oxidativo característicos de la HTA, además de alteraciones de la permeabilidad de la barrera hematoencefálica y el flujo sanguíneo cerebral. Gracias a que la HTA es un factor de riesgo modificable, se ha planteado entonces la interrogante de si su tratamiento oportuno podría ser un potencial mecanismo para la prevención o retraso del desarrollo de los trastornos cognitivos relacionados a la edad y aunque actualmente existen estudios que respalden dicha teoría, han de ser necesarios un mayor número de estudios al respecto. Es por ello que el objetivo de la presente investigación es describir los mecanismos fisiopatológicos conocidos hasta el momento que relacionan la HTA con el deterioro de la función cognitiva, y resumir la evidencia actual sobre la efectividad de los agentes antihipertensivos para la prevención o el retraso del deterioro cognitivo. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Síndrome Cardiometabólico is the property of Sindrome Cardiometabolico and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=161781859 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.5281/zenodo.6436925 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 5 StartPage: 34 Titles: – TitleFull: Hipertensión arterial y deterioro neurocognitivo: una relación bidireccional. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sánchez Montero, Génesis – PersonEntity: Name: NameFull: Gallo Valverde, Jean Carlos – PersonEntity: Name: NameFull: Logroño Bautista, Paola – PersonEntity: Name: NameFull: Quinteros Romero, Cesar – PersonEntity: Name: NameFull: Vázquez Verdugo, María – PersonEntity: Name: NameFull: Sinchi Chuqui, Carlos – PersonEntity: Name: NameFull: Cevallos Segovia, Pamela – PersonEntity: Name: NameFull: Garzón Quezada, Karina IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2021 Type: published Y: 2021 Identifiers: – Type: issn-print Value: 22447261 Numbering: – Type: volume Value: 11 – Type: issue Value: 1 Titles: – TitleFull: Síndrome Cardiometabólico Type: main |
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