Rabdomiólisis asociada con hipocalemia en el embarazo y aspectos perinatales. Reporte de un caso clínico.

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Title: Rabdomiólisis asociada con hipocalemia en el embarazo y aspectos perinatales. Reporte de un caso clínico.
Alternate Title: Rhabdomyolysis associated with hypokalemia in pregnancy and perinatal aspects. A case report.
Authors: Galván Luna, Adriana1, Rivas López, Radamés2,3 radamesrl@hotmail.com
Source: Ginecología y Obstetricia de México. nov2023, Vol. 91 Issue 11, p840-846. 7p.
Subjects: RHABDOMYOLYSIS, HYPOKALEMIA, PERINATAL care, PREGNANCY complications, PREGNANT women, CESAREAN section, ELECTROLYTES, PREECLAMPSIA
Abstract (English): BACKGROUND: Rhabdomyolysis is a syndrome, caused by injury to the muscle fiber, which produces the release of intracellular components such as myoglobin, creatine kinase, aldolase and lactate dehydrogenase, electrolytes, into the extracellular space and blood circulation, which can cause serious complications. such as cardiovascular disorders, cerebral edema and death. There are few reported cases of rhabdomyolysis in pregnancy, the reports described in the literature have been associated with infections and hydroelectrolytic changes. The clinical case is presented due to the importance of the repercussion to the maternal-fetal binomial, since it can result in a serious outcome. CLINICAL CASE: The case of a primiparous pregnant patient is presented, who debuted with clinical symptoms accompanied by muscular alterations after an infection, in week 18 of gestation, for which a study protocol was requested with the finding of hydroelectrolyte imbalance, of the hypokalemia type, with sudden elevation of creatine phosphokinase. A positive urine culture for Escherichia coli was found. Management with hydroelectrolyte replacement was indicated, with potassium replacement adjusted to requirements, antibiotic, and nutritional contribution, with hospital discharge after 2 days. Prenatal control was continued and at week 32.2 she presented preeclampsia, which is why a cesarean section was decided, a male weighing 2395 g, Apgar 9/9, with satisfactory evolution of the binomial was obtained. CONCLUSIONS: Pregnancy is more susceptible to infections or complications associated with hydroelectrolyte imbalances, rhabdomyolysis can occur in pregnancy, and it is important not to rule it out, its diagnosis can be made clinically and through laboratory tests. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): ANTECEDENTES: La rabdomiólisis es un síndrome causado por una lesión en las fibras musculares que produce la liberación de componentes intracelulares (mioglobina, creatinfosfocinasa, aldolasa y lactato deshidrogenasa; electrolitos) hacia el espacio extracelular y la circulación sanguínea, lo que resulta en complicaciones graves (alteraciones cardiovasculares, edema cerebral y muerte). Existen pocos casos reportados de rabdomiólisis durante el embarazo, los informes descritos en la bibliografía se enfocan en infecciones y alteraciones hidroelectrolíticas. CASO CLÍNICO: Paciente de 28 años, primigesta, que inició con alteraciones musculares luego de un cuadro infeccioso, en la semana 18 del embarazo, por lo que se le practicaron estudios para encontrar la causa del desequilibrio hidroelectrolítico (determinación de hipocalemia), con elevación súbita de creatinfosfocinasa. El urocultivo resultó positivo a Escherichia coli. El tratamiento consistió en reposición hidroelectrolítica, con administración de potasio ajustado a los requerimientos de la paciente, antibiótico y aporte nutricional, con alta hospitalaria a los dos días. Continuó en control prenatal y en la semana 32.2 tuvo preeclampsia, por lo que se decidió efectuar cesárea, de la que se obtuvo un recién nacido masculino, de 2395 g, Apgar 9/9, con evolución satisfactoria de la madre y su hijo. CONCLUSIONES: El embarazo es un estado fisiológico que implica mayor susceptibilidad de infecciones o complicaciones asociadas con desequilibrio hidroelectrolítico. Es importante considerar la rabdomiólisis durante el embarazo; el diagnóstico se establece mediante examen clínico y estudios de laboratorio. [ABSTRACT FROM AUTHOR]
Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Rabdomiólisis asociada con hipocalemia en el embarazo y aspectos perinatales. Reporte de un caso clínico.
– Name: TitleAlt
  Label: Alternate Title
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  Data: Rhabdomyolysis associated with hypokalemia in pregnancy and perinatal aspects. A case report.
– Name: Author
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  Data: <searchLink fieldCode="AR" term="%22Galván+Luna%2C+Adriana%22">Galván Luna, Adriana</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rivas+López%2C+Radamés%22">Rivas López, Radamés</searchLink><relatesTo>2,3</relatesTo><i> radamesrl@hotmail.com</i>
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  Data: <searchLink fieldCode="JN" term="%22Ginecología+y+Obstetricia+de+México%22">Ginecología y Obstetricia de México</searchLink>. nov2023, Vol. 91 Issue 11, p840-846. 7p.
– Name: Subject
  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22RHABDOMYOLYSIS%22">RHABDOMYOLYSIS</searchLink><br /><searchLink fieldCode="DE" term="%22HYPOKALEMIA%22">HYPOKALEMIA</searchLink><br /><searchLink fieldCode="DE" term="%22PERINATAL+care%22">PERINATAL care</searchLink><br /><searchLink fieldCode="DE" term="%22PREGNANCY+complications%22">PREGNANCY complications</searchLink><br /><searchLink fieldCode="DE" term="%22PREGNANT+women%22">PREGNANT women</searchLink><br /><searchLink fieldCode="DE" term="%22CESAREAN+section%22">CESAREAN section</searchLink><br /><searchLink fieldCode="DE" term="%22ELECTROLYTES%22">ELECTROLYTES</searchLink><br /><searchLink fieldCode="DE" term="%22PREECLAMPSIA%22">PREECLAMPSIA</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: BACKGROUND: Rhabdomyolysis is a syndrome, caused by injury to the muscle fiber, which produces the release of intracellular components such as myoglobin, creatine kinase, aldolase and lactate dehydrogenase, electrolytes, into the extracellular space and blood circulation, which can cause serious complications. such as cardiovascular disorders, cerebral edema and death. There are few reported cases of rhabdomyolysis in pregnancy, the reports described in the literature have been associated with infections and hydroelectrolytic changes. The clinical case is presented due to the importance of the repercussion to the maternal-fetal binomial, since it can result in a serious outcome. CLINICAL CASE: The case of a primiparous pregnant patient is presented, who debuted with clinical symptoms accompanied by muscular alterations after an infection, in week 18 of gestation, for which a study protocol was requested with the finding of hydroelectrolyte imbalance, of the hypokalemia type, with sudden elevation of creatine phosphokinase. A positive urine culture for Escherichia coli was found. Management with hydroelectrolyte replacement was indicated, with potassium replacement adjusted to requirements, antibiotic, and nutritional contribution, with hospital discharge after 2 days. Prenatal control was continued and at week 32.2 she presented preeclampsia, which is why a cesarean section was decided, a male weighing 2395 g, Apgar 9/9, with satisfactory evolution of the binomial was obtained. CONCLUSIONS: Pregnancy is more susceptible to infections or complications associated with hydroelectrolyte imbalances, rhabdomyolysis can occur in pregnancy, and it is important not to rule it out, its diagnosis can be made clinically and through laboratory tests. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: ANTECEDENTES: La rabdomiólisis es un síndrome causado por una lesión en las fibras musculares que produce la liberación de componentes intracelulares (mioglobina, creatinfosfocinasa, aldolasa y lactato deshidrogenasa; electrolitos) hacia el espacio extracelular y la circulación sanguínea, lo que resulta en complicaciones graves (alteraciones cardiovasculares, edema cerebral y muerte). Existen pocos casos reportados de rabdomiólisis durante el embarazo, los informes descritos en la bibliografía se enfocan en infecciones y alteraciones hidroelectrolíticas. CASO CLÍNICO: Paciente de 28 años, primigesta, que inició con alteraciones musculares luego de un cuadro infeccioso, en la semana 18 del embarazo, por lo que se le practicaron estudios para encontrar la causa del desequilibrio hidroelectrolítico (determinación de hipocalemia), con elevación súbita de creatinfosfocinasa. El urocultivo resultó positivo a Escherichia coli. El tratamiento consistió en reposición hidroelectrolítica, con administración de potasio ajustado a los requerimientos de la paciente, antibiótico y aporte nutricional, con alta hospitalaria a los dos días. Continuó en control prenatal y en la semana 32.2 tuvo preeclampsia, por lo que se decidió efectuar cesárea, de la que se obtuvo un recién nacido masculino, de 2395 g, Apgar 9/9, con evolución satisfactoria de la madre y su hijo. CONCLUSIONES: El embarazo es un estado fisiológico que implica mayor susceptibilidad de infecciones o complicaciones asociadas con desequilibrio hidroelectrolítico. Es importante considerar la rabdomiólisis durante el embarazo; el diagnóstico se establece mediante examen clínico y estudios de laboratorio. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.24245/gom.v91i11.8844
    Languages:
      – Code: spa
        Text: Spanish
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 840
    Subjects:
      – SubjectFull: RHABDOMYOLYSIS
        Type: general
      – SubjectFull: HYPOKALEMIA
        Type: general
      – SubjectFull: PERINATAL care
        Type: general
      – SubjectFull: PREGNANCY complications
        Type: general
      – SubjectFull: PREGNANT women
        Type: general
      – SubjectFull: CESAREAN section
        Type: general
      – SubjectFull: ELECTROLYTES
        Type: general
      – SubjectFull: PREECLAMPSIA
        Type: general
    Titles:
      – TitleFull: Rabdomiólisis asociada con hipocalemia en el embarazo y aspectos perinatales. Reporte de un caso clínico.
        Type: main
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            NameFull: Galván Luna, Adriana
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            NameFull: Rivas López, Radamés
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              M: 11
              Text: nov2023
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              Y: 2023
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              Value: 11
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