Hemoglobina reticulocitaria en donantes de sangre repetitivos, que acuden al banco de sangre de la Escuela de Microbiología de la Universidad de Antioquia.

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Bibliographic Details
Title:	Hemoglobina reticulocitaria en donantes de sangre repetitivos, que acuden al banco de sangre de la Escuela de Microbiología de la Universidad de Antioquia.
Alternate Title:	Reticulocyte hemoglobin in repetitive blood donors, who come to the blood bank of the School of Microbiology of the Universidad de Antioquia.
Authors:	López Vallejo, Yicel¹ yicellopezv@gmail.com, Acevedo Toro, Paola Andrea², Franco Aguirre, Jhon Querubín³, Restrepo Velásquez, Karen Stefanía⁴
Source:	CES Medicina. may-ago2023, Vol. 37 Issue 2, p13-24. 12p.
Abstract (English):	Introduction: repetitive blood donors can develop iron deficiency, reticulocyte hemoglobin is an effective auxiliary tool, which allows detecting early changes in the status of this element to be detected before anemia develops and microcytosis and hypochromia appear, as well as clinical symptoms. Objective: to determine the levels of reticulocyte hemoglobin, ferritin and erythroid parameters in repetitive blood donors, who attend the blood bank of the School of Microbiology of the University of Antioquia. Methods: Cross-sectional descriptive study that included 109 repetitive donors from the Blood Bank of the University of Antioquia. Ferritin, erythroid parameters, reticulocyte hemoglobin, and peripheral blood smear were evaluated. Summary measures and frequencies were calculated and the following statistical tests were used: Mann-Whitney U and Pearson or Spearman correlations, with a significance level of p<0.05. Results: 62.4% were women, the average age was 37 year. Iron deficiency was observed in 6.4% of the total population and low reticulocyte hemoglobin in 3.70%. This presented a weak positive correlation with ferritin and a statistically significant association with gender. Conclusions: It is important to prevent the development of iron deficiency in repetitive blood donors, the implementation of the type VI hemogram that includes the reticulogram could help improve the criteria for selecting and monitoring donors. [ABSTRACT FROM AUTHOR]
Abstract (Spanish):	Introducción: los donantes repetitivos de sangre pueden desarrollar deficiencia de hierro, la hemoglobina reticulocitaria es una herramienta auxiliar eficaz, que permite detectar cambios tempranos en el estado de éste elemento antes que se desarrolle una anemia y aparezca la microcitosis e hipocromía, al igual que la sintomatología clínica. Objetivo: determinar los niveles de hemoglobina reticulocitaria, ferritina y parámetros eritroides en donantes de sangre repetitivos, que acuden al banco de sangre de la Escuela de Microbiología de la Universidad de Antioquia. Métodos: estudio descriptivo transversal que incluyó 109 donantes repetitivos del Banco de Sangre de la Universidad de Antioquia. Se evaluaron la ferritina, los parámetros eritroides, la hemoglobina reticulocitaria y el extendido de sangre periférica. Se calcularon medidas de resumen, frecuencias y se utilizaron las siguientes pruebas estadísticas: U de Mann Withney y correlaciones de Pearson o Spearman, con un nivel de significación de p< 0,05. Resultados: el 62,4% fueron mujeres, la edad promedio fue de 37 años. Se observó ferropenia en el 6,4% del total de la población y hemoglobina reticulocitaria baja en el 3,70%, ésta presentó una correlación positiva débil con la ferritina y asociación estadísticamente significativa con el sexo. Conclusiones: es importante prevenir el desarrollo de deficiencia de hierro en los donantes de sangre repetitivos, la implementación del hemograma tipo VI que incluya el reticulograma, podría ayudar a mejorar los criterios de selección y seguimiento de los donantes. [ABSTRACT FROM AUTHOR]
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Database:	MedicLatina

Description
Abstract:	Introduction: repetitive blood donors can develop iron deficiency, reticulocyte hemoglobin is an effective auxiliary tool, which allows detecting early changes in the status of this element to be detected before anemia develops and microcytosis and hypochromia appear, as well as clinical symptoms. Objective: to determine the levels of reticulocyte hemoglobin, ferritin and erythroid parameters in repetitive blood donors, who attend the blood bank of the School of Microbiology of the University of Antioquia. Methods: Cross-sectional descriptive study that included 109 repetitive donors from the Blood Bank of the University of Antioquia. Ferritin, erythroid parameters, reticulocyte hemoglobin, and peripheral blood smear were evaluated. Summary measures and frequencies were calculated and the following statistical tests were used: Mann-Whitney U and Pearson or Spearman correlations, with a significance level of p<0.05. Results: 62.4% were women, the average age was 37 year. Iron deficiency was observed in 6.4% of the total population and low reticulocyte hemoglobin in 3.70%. This presented a weak positive correlation with ferritin and a statistically significant association with gender. Conclusions: It is important to prevent the development of iron deficiency in repetitive blood donors, the implementation of the type VI hemogram that includes the reticulogram could help improve the criteria for selecting and monitoring donors. [ABSTRACT FROM AUTHOR]
ISSN:	01208705
DOI:	10.21615/cesmedicina.7266