Early and contemporary drivers of the HIV-1 group M pandemic.
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| Title: | Early and contemporary drivers of the HIV-1 group M pandemic. |
|---|---|
| Authors: | Brennan-Calland, Jude P.1 jude.brennan-calland@student.manchester.ac.uk |
| Source: | AIDS Reviews. Jan-Mar2024, Vol. 26 Issue 1, p23-31. 9p. |
| Subjects: | HIV, HEALTH policy, PANDEMICS, PHYLOGENETIC models, ECONOMIC expansion |
| Abstract: | HIV emerged silently taking time to spread and become visible only through geographically isolated clusters of life-threatening immunodeficiency, known as AIDS since the early 80s. The clusters of infection expanded, overlapping to evolve into a pandemic that is ongoing and almost as silent. Phylogenetic analysis places the emergence of HIV-1 group M, the subtype responsible for the pandemic, in the human population more than 100 years ago. Once established, the rate and direction of spread of HIV-1 from local, to national, to contemporary pandemic proportions have varied over time and place. The literature presents many theories on the emergence and drivers of the spread of the virus over the past century. Here, historical evidence and phylogenetic models are reviewed to seek clarity on the emergence, geographic spread and key world events that mark the progression of the HIV-1 pandemic. This narrative review places particular focus on: war (both its direct and indirect affects), trade and economic expansion, changes in sexual behaviors, and public health policy. Investigating the impact of major world events and policy on the emergence and spread of HIV-1 may aid better understanding of what influences the viruses transmission dynamic. By identifying multilateral targets that influence transmission, up-scaled efforts to effectively control, if not remove, HIV-1 from the human population become a possibility. Suggestions for revisions in HIV-1 global public health policy are discussed. Refocused efforts to tackle HIV-1 transmission and replace the need to manage the pathology of this terrible disease are both ethically and economically just. [ABSTRACT FROM AUTHOR] |
| Copyright of AIDS Reviews is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 176370035 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Early and contemporary drivers of the HIV-1 group M pandemic. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Brennan-Calland%2C+Jude+P%2E%22">Brennan-Calland, Jude P.</searchLink><relatesTo>1</relatesTo><i> jude.brennan-calland@student.manchester.ac.uk</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22AIDS+Reviews%22">AIDS Reviews</searchLink>. Jan-Mar2024, Vol. 26 Issue 1, p23-31. 9p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22HIV%22">HIV</searchLink><br /><searchLink fieldCode="DE" term="%22HEALTH+policy%22">HEALTH policy</searchLink><br /><searchLink fieldCode="DE" term="%22PANDEMICS%22">PANDEMICS</searchLink><br /><searchLink fieldCode="DE" term="%22PHYLOGENETIC+models%22">PHYLOGENETIC models</searchLink><br /><searchLink fieldCode="DE" term="%22ECONOMIC+expansion%22">ECONOMIC expansion</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: HIV emerged silently taking time to spread and become visible only through geographically isolated clusters of life-threatening immunodeficiency, known as AIDS since the early 80s. The clusters of infection expanded, overlapping to evolve into a pandemic that is ongoing and almost as silent. Phylogenetic analysis places the emergence of HIV-1 group M, the subtype responsible for the pandemic, in the human population more than 100 years ago. Once established, the rate and direction of spread of HIV-1 from local, to national, to contemporary pandemic proportions have varied over time and place. The literature presents many theories on the emergence and drivers of the spread of the virus over the past century. Here, historical evidence and phylogenetic models are reviewed to seek clarity on the emergence, geographic spread and key world events that mark the progression of the HIV-1 pandemic. This narrative review places particular focus on: war (both its direct and indirect affects), trade and economic expansion, changes in sexual behaviors, and public health policy. Investigating the impact of major world events and policy on the emergence and spread of HIV-1 may aid better understanding of what influences the viruses transmission dynamic. By identifying multilateral targets that influence transmission, up-scaled efforts to effectively control, if not remove, HIV-1 from the human population become a possibility. Suggestions for revisions in HIV-1 global public health policy are discussed. Refocused efforts to tackle HIV-1 transmission and replace the need to manage the pathology of this terrible disease are both ethically and economically just. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of AIDS Reviews is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=176370035 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.24875/AIDSRev.23000021 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 9 StartPage: 23 Subjects: – SubjectFull: HIV Type: general – SubjectFull: HEALTH policy Type: general – SubjectFull: PANDEMICS Type: general – SubjectFull: PHYLOGENETIC models Type: general – SubjectFull: ECONOMIC expansion Type: general Titles: – TitleFull: Early and contemporary drivers of the HIV-1 group M pandemic. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Brennan-Calland, Jude P. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan-Mar2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 11396121 Numbering: – Type: volume Value: 26 – Type: issue Value: 1 Titles: – TitleFull: AIDS Reviews Type: main |
| ResultId | 1 |
