El índice inmunidad-inflamación sistémica preoperatorio como indicador del estadio clínico en el carcinoma de células renales.
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| Title: | El índice inmunidad-inflamación sistémica preoperatorio como indicador del estadio clínico en el carcinoma de células renales. |
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| Alternate Title: | The preoperative systemic immune-inflammatory index as indicator of clinical stage in renal cell carcinoma. |
| Authors: | Ricárdez-Espinosa, Abel A.1, Rojas-Hernández, Erick1, Reyes-Ruiz, José M.2,3, Salazar-Angulo, Javier F.1, Jiménez-López, Luis A.1,2 luisalfredjimenez@hotmail.com |
| Source: | Boletín del Colegio Mexicano de Urología. jul-sep2023, Vol. 38 Issue 3, p93-97. 5p. |
| Abstract (English): | Objective: To evaluate the usefulness of the preoperative systemic immune-inflammatory index (SII) as predictor of locally advanced or metastatic renal cell carcinoma (RCC). Method: Retrospective, single-center, observational and analytical study performed in a tertiary hospital in Mexico. Patients diagnosed with CRC during January 2021 to July 2022 were included and stratified into localized CRC (clinical stage I and II) and locally advanced or metastatic CRC (clinical stage III and IV). Spearman correlation analysis, receiver operating characteristic (ROC) curve and Youden index were performed. Results: A total of 85 patients with clinical stage I-II (n = 35) and III-IV (n = 50) CRC were included in the study. Forty-seven patients (56%) were male and thirty-eight (44%) were female. The median age for stage I-II patients was 59.06 (12.433) years and for stage III-IV patients was 61.83 (10.001) years (p = 0.416). IIS correlated with tumor size (r = 0.376; p = 0.001) and had an area under the curve of 0.77 (95% confidence interval: 0.66-0.85; p < 0.0001). The optimal cutoff point for IIS was > 637.2829, with a sensitivity of 74% and a specificity of 71.43%. Conclusions: This study demonstrated the correlation between IIS and tumor size. Preoperative IIS could be an indicator of clinical stage III-IV CRC. IIS is an effective and simple clinical tool in the preoperative evaluation of patients diagnosed with CRC. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Objetivo: Evaluar la utilidad del índice inmunidad-inflamación sistémica (IIS) preoperatorio como predictor en el carcinoma de células renales (CCR) localmente avanzado o metastásico. Método: Estudio retrospectivo, unicéntrico, observacional y analítico, realizado en un hospital de tercer nivel en Mexico. Se incluyeron pacientes diagnosticados con CCR durante enero de 2021 a julio de 2022 y se estratificaron en CCR localizado (estadio clínico I y II) y CCR localmente avanzado o metastásico (estadio clínico III y IV). Se realizaron análisis de correlación de Spearman, curva ROC (Receiver Operating Characteristic) e índice de Youden. Resultados: Fueron incluidos 85 pacientes con CCR en estadio clínico I-II (n = 35) y III-IV (n = 50). De ellos, 47 (56%) eran hombres y 38 (44%) mujeres. La mediana de edad de los pacientes en estadio I-II fue de 59.06 (12.433) años y la de los pacientes en estadio III-IV fue de 61.83 (10.001) años (p = 0.416). El IIS se correlacionó con el tamaño del tumor (r = 0.376; p= 0.001) y tuvo un área bajo la curva de 0.77 (intervalo de confianza del 95%: 0.66-0.85; p < 0.0001). El punto de corte óptimo para el IIS fue > 637.2829, con una sensibilidad del 74% y una especificidad del 71.43%. Conclusiones: Existe correlación entre el IIS y el tamaño del tumor. Por ello, el IIS preoperatorio es un indicador de CCR en estadio clínico III-IV. El IIS es una herramienta clínica efectiva y sencilla en la evaluación preoperatoria de pacientes con diagnóstico de CCR. [ABSTRACT FROM AUTHOR] |
| Copyright of Boletín del Colegio Mexicano de Urología is the property of Colegio Mexicano de Urologia A.C. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
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| Items | – Name: Title Label: Title Group: Ti Data: El índice inmunidad-inflamación sistémica preoperatorio como indicador del estadio clínico en el carcinoma de células renales. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: The preoperative systemic immune-inflammatory index as indicator of clinical stage in renal cell carcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Ricárdez-Espinosa%2C+Abel+A%2E%22">Ricárdez-Espinosa, Abel A.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rojas-Hernández%2C+Erick%22">Rojas-Hernández, Erick</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Reyes-Ruiz%2C+José+M%2E%22">Reyes-Ruiz, José M.</searchLink><relatesTo>2,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Salazar-Angulo%2C+Javier+F%2E%22">Salazar-Angulo, Javier F.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Jiménez-López%2C+Luis+A%2E%22">Jiménez-López, Luis A.</searchLink><relatesTo>1,2</relatesTo><i> luisalfredjimenez@hotmail.com</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Boletín+del+Colegio+Mexicano+de+Urología%22">Boletín del Colegio Mexicano de Urología</searchLink>. jul-sep2023, Vol. 38 Issue 3, p93-97. 5p. – Name: Abstract Label: Abstract (English) Group: Ab Data: Objective: To evaluate the usefulness of the preoperative systemic immune-inflammatory index (SII) as predictor of locally advanced or metastatic renal cell carcinoma (RCC). Method: Retrospective, single-center, observational and analytical study performed in a tertiary hospital in Mexico. Patients diagnosed with CRC during January 2021 to July 2022 were included and stratified into localized CRC (clinical stage I and II) and locally advanced or metastatic CRC (clinical stage III and IV). Spearman correlation analysis, receiver operating characteristic (ROC) curve and Youden index were performed. Results: A total of 85 patients with clinical stage I-II (n = 35) and III-IV (n = 50) CRC were included in the study. Forty-seven patients (56%) were male and thirty-eight (44%) were female. The median age for stage I-II patients was 59.06 (12.433) years and for stage III-IV patients was 61.83 (10.001) years (p = 0.416). IIS correlated with tumor size (r = 0.376; p = 0.001) and had an area under the curve of 0.77 (95% confidence interval: 0.66-0.85; p < 0.0001). The optimal cutoff point for IIS was > 637.2829, with a sensitivity of 74% and a specificity of 71.43%. Conclusions: This study demonstrated the correlation between IIS and tumor size. Preoperative IIS could be an indicator of clinical stage III-IV CRC. IIS is an effective and simple clinical tool in the preoperative evaluation of patients diagnosed with CRC. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Objetivo: Evaluar la utilidad del índice inmunidad-inflamación sistémica (IIS) preoperatorio como predictor en el carcinoma de células renales (CCR) localmente avanzado o metastásico. Método: Estudio retrospectivo, unicéntrico, observacional y analítico, realizado en un hospital de tercer nivel en Mexico. Se incluyeron pacientes diagnosticados con CCR durante enero de 2021 a julio de 2022 y se estratificaron en CCR localizado (estadio clínico I y II) y CCR localmente avanzado o metastásico (estadio clínico III y IV). Se realizaron análisis de correlación de Spearman, curva ROC (Receiver Operating Characteristic) e índice de Youden. Resultados: Fueron incluidos 85 pacientes con CCR en estadio clínico I-II (n = 35) y III-IV (n = 50). De ellos, 47 (56%) eran hombres y 38 (44%) mujeres. La mediana de edad de los pacientes en estadio I-II fue de 59.06 (12.433) años y la de los pacientes en estadio III-IV fue de 61.83 (10.001) años (p = 0.416). El IIS se correlacionó con el tamaño del tumor (r = 0.376; p= 0.001) y tuvo un área bajo la curva de 0.77 (intervalo de confianza del 95%: 0.66-0.85; p < 0.0001). El punto de corte óptimo para el IIS fue > 637.2829, con una sensibilidad del 74% y una especificidad del 71.43%. Conclusiones: Existe correlación entre el IIS y el tamaño del tumor. Por ello, el IIS preoperatorio es un indicador de CCR en estadio clínico III-IV. El IIS es una herramienta clínica efectiva y sencilla en la evaluación preoperatoria de pacientes con diagnóstico de CCR. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Boletín del Colegio Mexicano de Urología is the property of Colegio Mexicano de Urologia A.C. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.24875/BCMU.23000015 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 5 StartPage: 93 Titles: – TitleFull: El índice inmunidad-inflamación sistémica preoperatorio como indicador del estadio clínico en el carcinoma de células renales. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ricárdez-Espinosa, Abel A. – PersonEntity: Name: NameFull: Rojas-Hernández, Erick – PersonEntity: Name: NameFull: Reyes-Ruiz, José M. – PersonEntity: Name: NameFull: Salazar-Angulo, Javier F. – PersonEntity: Name: NameFull: Jiménez-López, Luis A. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: jul-sep2023 Type: published Y: 2023 Identifiers: – Type: issn-print Value: 01874829 Numbering: – Type: volume Value: 38 – Type: issue Value: 3 Titles: – TitleFull: Boletín del Colegio Mexicano de Urología Type: main |
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