Resultados clínicos del uso de oseltamivir en suspensión en pacientes pediátricos con influenza o enfermedad tipo influenza.

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Title: Resultados clínicos del uso de oseltamivir en suspensión en pacientes pediátricos con influenza o enfermedad tipo influenza.
Alternate Title: Clinical outcomes of using oseltamivir suspension in pediatric patients with influenza or influenza-like illness.
Authors: Alejandro Vázquez-Narváez, Jorge1, Angélica Rochín-Kobashi, Ilya2, Berenice García-Robles, Manuela3, Delgado-Roche, Livan4 ldelgado@liomont.com.mx
Source: Revista Mexicana de Pediatria. sep/oct2023, Vol. 90 Issue 5, p176-179. 4p.
Abstract (English): Introduction: oseltamivir is a potent inhibitor of the neuraminidase of the influenza virus, which shortens the duration of influenza symptoms. Objective: to describe the clinical outcome of using oseltamivir suspension in children with influenza or influenza-like illness. Material and methods: clinical, observational, prospective, and multicenter study. Population: children aged two to 12 years diagnosed with influenza or influenza-like illness who received oseltamivir suspension (Seltaferon®) for five days. The outcome measures were clinical evolution (assessed by CARIFS scale) and frequency of adverse events (AEs). Results: 35 patients were included, with a mean age of 5.2 ± 2.7 years. By day 5, 32 patients had clinical improvement; Regarding safety, there were eight patients in whom 18 AEs were recorded, which were mild or moderate. Conclusions: oseltamivir suspension is a treatment that seems to be useful and safe in pediatric population with influenza. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción: oseltamivir es un potente inhibidor de la neuraminidasa del virus de influenza, que acorta la duración de los síntomas de influenza. Objetivo: describir los resultados clínicos del uso de oseltamivir suspensión en niños con influenza o enfermedad tipo influenza. Material y métodos: estudio clínico, observacional, prospectivo y multicéntrico. Población: niños de dos a 12 años con diagnóstico de influenza o enfermedad tipo influenza que recibieron oseltamivir suspensión (Seltaferon®) durante cinco días. Las variables de resultado fueron: evolución clínica (evaluado por escala CARIFS) y la frecuencia de eventos adversos (EA). Resultados: se incluyeron 35 pacientes; promedio de edad, 5.2 ± 2.7 años. Para el día 5, 32 pacientes tuvieron mejoría clínica; en cuanto a seguridad, hubo ocho pacientes en quienes se registraron 18 EA, los cuales fueron leves o moderados. Conclusiones: oseltamivir suspensión es un tratamiento que parece ser útil y seguro en población pediátrica con influenza. [ABSTRACT FROM AUTHOR]
Copyright of Revista Mexicana de Pediatria is the property of Sociedad Mexicana de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Resultados clínicos del uso de oseltamivir en suspensión en pacientes pediátricos con influenza o enfermedad tipo influenza.
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  Data: Clinical outcomes of using oseltamivir suspension in pediatric patients with influenza or influenza-like illness.
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  Data: <searchLink fieldCode="AR" term="%22Alejandro+Vázquez-Narváez%2C+Jorge%22">Alejandro Vázquez-Narváez, Jorge</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Angélica+Rochín-Kobashi%2C+Ilya%22">Angélica Rochín-Kobashi, Ilya</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Berenice+García-Robles%2C+Manuela%22">Berenice García-Robles, Manuela</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Delgado-Roche%2C+Livan%22">Delgado-Roche, Livan</searchLink><relatesTo>4</relatesTo><i> ldelgado@liomont.com.mx</i>
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  Data: <searchLink fieldCode="JN" term="%22Revista+Mexicana+de+Pediatria%22">Revista Mexicana de Pediatria</searchLink>. sep/oct2023, Vol. 90 Issue 5, p176-179. 4p.
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Introduction: oseltamivir is a potent inhibitor of the neuraminidase of the influenza virus, which shortens the duration of influenza symptoms. Objective: to describe the clinical outcome of using oseltamivir suspension in children with influenza or influenza-like illness. Material and methods: clinical, observational, prospective, and multicenter study. Population: children aged two to 12 years diagnosed with influenza or influenza-like illness who received oseltamivir suspension (Seltaferon®) for five days. The outcome measures were clinical evolution (assessed by CARIFS scale) and frequency of adverse events (AEs). Results: 35 patients were included, with a mean age of 5.2 ± 2.7 years. By day 5, 32 patients had clinical improvement; Regarding safety, there were eight patients in whom 18 AEs were recorded, which were mild or moderate. Conclusions: oseltamivir suspension is a treatment that seems to be useful and safe in pediatric population with influenza. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Introducción: oseltamivir es un potente inhibidor de la neuraminidasa del virus de influenza, que acorta la duración de los síntomas de influenza. Objetivo: describir los resultados clínicos del uso de oseltamivir suspensión en niños con influenza o enfermedad tipo influenza. Material y métodos: estudio clínico, observacional, prospectivo y multicéntrico. Población: niños de dos a 12 años con diagnóstico de influenza o enfermedad tipo influenza que recibieron oseltamivir suspensión (Seltaferon®) durante cinco días. Las variables de resultado fueron: evolución clínica (evaluado por escala CARIFS) y la frecuencia de eventos adversos (EA). Resultados: se incluyeron 35 pacientes; promedio de edad, 5.2 ± 2.7 años. Para el día 5, 32 pacientes tuvieron mejoría clínica; en cuanto a seguridad, hubo ocho pacientes en quienes se registraron 18 EA, los cuales fueron leves o moderados. Conclusiones: oseltamivir suspensión es un tratamiento que parece ser útil y seguro en población pediátrica con influenza. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Revista Mexicana de Pediatria is the property of Sociedad Mexicana de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: sep/oct2023
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