PERIODONTITIS APICAL Y SUS EFECTOS SOBRE EL TEJIDO RENAL EN RATAS.
Saved in:
| Title: | PERIODONTITIS APICAL Y SUS EFECTOS SOBRE EL TEJIDO RENAL EN RATAS. |
|---|---|
| Alternate Title: | APICAL PERIODONTITIS AND ITS EFFECTS ON RENAL TISSUE IN RATS. |
| Authors: | Mireya Jara, Cynthia1, Raquel Ramírez, Roccio2, Susana Barreto, Regina2, García-Salinas, Héctor2, Gabriel Adorno, Carlos1 cgadorno@founa.edu.py, Fretes, Vicente1, Paola Amarilla, Shyrley3, Díaz-Reissner, Clarisse1 |
| Source: | Revista Peruana de Medicina Experimental y Salud Pública. 2024, Vol. 41 Issue 4, p385-391. 7p. |
| Subjects: | LABORATORY rats, PERIAPICAL periodontitis, BLOOD pressure, PLETHYSMOGRAPHY, CHRONIC kidney failure |
| Abstract (English): | Objetives. To evaluate the effect of apical periodontitis (AP) induced in Wistar rats on histologically examined renal tissue. Materials and methods. Fourteen 12-week-old male Wistar rats weighing an average of 250 grams were used. AP was induced with pulp exposure of the upper and lower first molars using a #1011 HL spherical bur in high rotation. The lesions were left exposed to the oral environment for a period of 7 weeks. Blood pressure was measured by the tail-cuff plethysmography method from the fourth week. The kidney was dissected for histological analysis (H&E). Mann-Whitney and Student's t-test were used for non-parametric and parametric data, respectively, with a significance level of 5%. Results. A statistically significant increase in both Bowman's space area and renal corpuscle area was found in the AP group (p<0.05). The AP group had a higher percentage of renal tissue with inflammatory infiltrate, but without significant difference. Blood pressure did change during the experimental period and no difference was identified between the groups. Conclusions. Induction of AP in Wistar rats resulted in significant changes of certain renal histological parameters, suggesting a possible interaction between AP and renal tissue that requires further research. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Objetivos. Evaluar el efecto de la periodontitis apical (PA) inducida en ratas Wistar sobre el tejido renal examinado histológicamente. Materiales y métodos. Fueron utilizadas 14 ratas Wistar macho, de 12 semanas y 250 gramos promedio. La PA fue inducida con la exposición pulpar de los primeros molares superiores e inferiores utilizando una fresa esférica #1011 HL en alta rotación. Las lesiones se dejaron expuestas al medio bucal por un periodo de 7 semanas. La presión arterial fue medida mediante el método de pletismografía del manguito de la cola a partir de la cuarta semana. Fue realizada la disección del riñón para análisis histológico (H&E). Fue utilizada la prueba de Mann-Whitney y t de Student para datos no paramétricos y paramétricos, respectivamente, con un nivel de significancia del 5%. Resultados. Se observó un aumento estadísticamente significativo tanto en el área del espacio de Bowman como en el área del corpúsculo renal en el grupo PA (p<0,05). El grupo con PA presentó mayor porcentaje de tejido renal con infiltrado inflamatorio, pero sin diferencia significativa. La presión arterial no sufrió modificaciones durante el periodo experimental y no fue identificada diferencia entre los grupos. Conclusiones. La inducción de PA en ratas Wistar resultó en modificaciones significativas de ciertos parámetros histológicos renales, sugiriendo una posible interacción entre la PA y el tejido renal que requiere de investigaciones adicionales. [ABSTRACT FROM AUTHOR] |
| Copyright of Revista Peruana de Medicina Experimental y Salud Pública is the property of Instituto Nacional de Salud (Peru) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: lth DbLabel: MedicLatina An: 181882680 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: PERIODONTITIS APICAL Y SUS EFECTOS SOBRE EL TEJIDO RENAL EN RATAS. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: APICAL PERIODONTITIS AND ITS EFFECTS ON RENAL TISSUE IN RATS. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Mireya+Jara%2C+Cynthia%22">Mireya Jara, Cynthia</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Raquel+Ramírez%2C+Roccio%22">Raquel Ramírez, Roccio</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Susana+Barreto%2C+Regina%22">Susana Barreto, Regina</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22García-Salinas%2C+Héctor%22">García-Salinas, Héctor</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Gabriel+Adorno%2C+Carlos%22">Gabriel Adorno, Carlos</searchLink><relatesTo>1</relatesTo><i> cgadorno@founa.edu.py</i><br /><searchLink fieldCode="AR" term="%22Fretes%2C+Vicente%22">Fretes, Vicente</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Paola+Amarilla%2C+Shyrley%22">Paola Amarilla, Shyrley</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Díaz-Reissner%2C+Clarisse%22">Díaz-Reissner, Clarisse</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Revista+Peruana+de+Medicina+Experimental+y+Salud+Pública%22">Revista Peruana de Medicina Experimental y Salud Pública</searchLink>. 2024, Vol. 41 Issue 4, p385-391. 7p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22LABORATORY+rats%22">LABORATORY rats</searchLink><br /><searchLink fieldCode="DE" term="%22PERIAPICAL+periodontitis%22">PERIAPICAL periodontitis</searchLink><br /><searchLink fieldCode="DE" term="%22BLOOD+pressure%22">BLOOD pressure</searchLink><br /><searchLink fieldCode="DE" term="%22PLETHYSMOGRAPHY%22">PLETHYSMOGRAPHY</searchLink><br /><searchLink fieldCode="DE" term="%22CHRONIC+kidney+failure%22">CHRONIC kidney failure</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Objetives. To evaluate the effect of apical periodontitis (AP) induced in Wistar rats on histologically examined renal tissue. Materials and methods. Fourteen 12-week-old male Wistar rats weighing an average of 250 grams were used. AP was induced with pulp exposure of the upper and lower first molars using a #1011 HL spherical bur in high rotation. The lesions were left exposed to the oral environment for a period of 7 weeks. Blood pressure was measured by the tail-cuff plethysmography method from the fourth week. The kidney was dissected for histological analysis (H&E). Mann-Whitney and Student's t-test were used for non-parametric and parametric data, respectively, with a significance level of 5%. Results. A statistically significant increase in both Bowman's space area and renal corpuscle area was found in the AP group (p<0.05). The AP group had a higher percentage of renal tissue with inflammatory infiltrate, but without significant difference. Blood pressure did change during the experimental period and no difference was identified between the groups. Conclusions. Induction of AP in Wistar rats resulted in significant changes of certain renal histological parameters, suggesting a possible interaction between AP and renal tissue that requires further research. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Objetivos. Evaluar el efecto de la periodontitis apical (PA) inducida en ratas Wistar sobre el tejido renal examinado histológicamente. Materiales y métodos. Fueron utilizadas 14 ratas Wistar macho, de 12 semanas y 250 gramos promedio. La PA fue inducida con la exposición pulpar de los primeros molares superiores e inferiores utilizando una fresa esférica #1011 HL en alta rotación. Las lesiones se dejaron expuestas al medio bucal por un periodo de 7 semanas. La presión arterial fue medida mediante el método de pletismografía del manguito de la cola a partir de la cuarta semana. Fue realizada la disección del riñón para análisis histológico (H&E). Fue utilizada la prueba de Mann-Whitney y t de Student para datos no paramétricos y paramétricos, respectivamente, con un nivel de significancia del 5%. Resultados. Se observó un aumento estadísticamente significativo tanto en el área del espacio de Bowman como en el área del corpúsculo renal en el grupo PA (p<0,05). El grupo con PA presentó mayor porcentaje de tejido renal con infiltrado inflamatorio, pero sin diferencia significativa. La presión arterial no sufrió modificaciones durante el periodo experimental y no fue identificada diferencia entre los grupos. Conclusiones. La inducción de PA en ratas Wistar resultó en modificaciones significativas de ciertos parámetros histológicos renales, sugiriendo una posible interacción entre la PA y el tejido renal que requiere de investigaciones adicionales. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Revista Peruana de Medicina Experimental y Salud Pública is the property of Instituto Nacional de Salud (Peru) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=181882680 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.17843/rpmesp.2014.314.13947 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 7 StartPage: 385 Subjects: – SubjectFull: LABORATORY rats Type: general – SubjectFull: PERIAPICAL periodontitis Type: general – SubjectFull: BLOOD pressure Type: general – SubjectFull: PLETHYSMOGRAPHY Type: general – SubjectFull: CHRONIC kidney failure Type: general Titles: – TitleFull: PERIODONTITIS APICAL Y SUS EFECTOS SOBRE EL TEJIDO RENAL EN RATAS. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mireya Jara, Cynthia – PersonEntity: Name: NameFull: Raquel Ramírez, Roccio – PersonEntity: Name: NameFull: Susana Barreto, Regina – PersonEntity: Name: NameFull: García-Salinas, Héctor – PersonEntity: Name: NameFull: Gabriel Adorno, Carlos – PersonEntity: Name: NameFull: Fretes, Vicente – PersonEntity: Name: NameFull: Paola Amarilla, Shyrley – PersonEntity: Name: NameFull: Díaz-Reissner, Clarisse IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 17264634 Numbering: – Type: volume Value: 41 – Type: issue Value: 4 Titles: – TitleFull: Revista Peruana de Medicina Experimental y Salud Pública Type: main |
| ResultId | 1 |
