Aspectos epidemiológicos y de manejo clínico relativos a las Infecciones del tracto urinario diagnosticadas en urgencias en pacientes mayores en España: Resultados del estudio EDEN-36.
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| Title: | Aspectos epidemiológicos y de manejo clínico relativos a las Infecciones del tracto urinario diagnosticadas en urgencias en pacientes mayores en España: Resultados del estudio EDEN-36. |
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| Alternate Title: | Epidemiological and clinical management aspects related to urinary tract infections diagnosed in the emergency department in elderly patients in Spain: Results of the EDEN-36 study. |
| Authors: | Salmerón Béliz, Octavio José1 octaviojose.salmeron@salud.madrid.org, Pérez-Fernández, Elia2, Miró, Òscar3, Aguiló, Sira3, Burillo-Putze, Guillermo4, Alquézar-Arbé, Aitor5, Fernández-Alonso, Cesáreo6, Jacob, Javier7, Montero Pérez, Francisco Javier8, Melcon Villalibre, Alejandro6, Cuerpo Cardeñosa, Sandra3, Serrano Lázaro, Leticia9, Caballero Martínez, María10, Muñoz Soler, Esther11, Bajo Fernández, Inmaculada12, Castuera Gil, Ana Isabel13, Hernando González, Rocío14, Carbó-Jordá, Albert15, Cabrera Rodrigo, Irene16, Gros Bañeres, Belén17 |
| Source: | Revista Española de Quimioterapia. feb2025, Vol. 38 Issue 1, p28-39. 12p. |
| Subjects: | OLDER patients, EMERGENCY room visits, URINARY tract infections, HOSPITAL mortality, HOSPITAL patients |
| Abstract (English): | Objective. To estimate the incidence of urinary tract infections (UTI) in elderly patients in Spanish emergency departments (ED), the need for hospitalization, diagnostic confirmation in hospitalized patients, adverse events and the predictive capacity of several biomarkers. Methods. In this a posteriori substudy of a generic study of reasons for ED visits in elderly patients, we included patients aged =65 years seen in 52 Spanish EDs for 1 week, selecting those diagnosed with UTI. As adverse events, in-hospital and 30-day mortality and combined adverse event (death or hospitalization) at 30 days post-discharge were collected. Relative risks (RR) were calculated. The predictive capacity of 10 variables and 6 biomarkers was investigated. Results. A total of 25,375 patients were included, 1058 with UTI (annual incidence: 24.7 per 1000 inhabitants aged =65 years and year, 95%CI: 24.5-24.9). A total of 36.5% were hospitalized, and in 80% the diagnosis of UTI was confirmed at discharge. Overall 30-day mortality was 5.4% and in-hospital mortality was 3.4%. Functional dependence was associated with both events (RR:2.91;1.18-7.17 and RR:12.61;1.47-108.11, respectively), as was having a CRP greater than 100 mg/L (RR:2.24;1.17-4.30 and RR:3.21;1.37-7.51, respectively). The combined post-high event occurred in 10.6%, and was associated with functional dependence (RR:2.05;1.04-4.06). CRP and hemoglobin had significant value in predicting 30-day post-discharge mortality or hospitalization. Conclusions. UTI is a frequent diagnosis in elderly patients consulting in the ED. Functional dependence is the best factor associated with adverse events. The biomarkers analyzed do not have a good predictive capacity. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Objetivo. Estimar la incidencia de infecciones del tracto urinario (ITU) en pacientes mayores en los servicios de urgencias (SU) españoles, la necesidad de hospitalización, la confirmación diagnóstica en pacientes hospitalizados, los eventos adversos y la capacidad predictiva de varios biomarcadores. Método. En este subestudio a posteriori de un estudio genérico de motivos de consulta en urgencias de pacientes de edad avanzada, se incluyeron pacientes de =65 años atendidos en 52 SU españoles durante 1 semana seleccionándose los diagnosticados de ITU. Como eventos adversos, se recogió mortalidad intrahospitalaria y a 30 días, y evento adverso combinado (muerte u hospitalización) a 30 días posalta. Se calcularon los riesgos relativos (RR). Se investigó la capacidad predictiva de 10 variables, y de 6 biomarcadores. Resultados. Se incluyeron 25.375 pacientes, 1.058 con ITU (incidencia anual: 24.7 por 1000 habitantes =65 años y año, IC95%:24,5-24,9). El 36,5% fue hospitalizado, y en el 80% el diagnóstico de ITU constaba al alta. La mortalidad global a 30 días fue del 5,4% y la intrahospitalaria del 3,4%. La dependencia funcional se asoció a ambos eventos (RR:2,91;1,18-7,17 y RR:12,61;1,47-108,11, respectivamente), así como tener una PCR mayor de 100 mg/L (RR:2,24;1,17-4,30 y RR:3,21;1,37-7,51, respectivamente). El evento combinado posalta ocurrió en el 10,6%, y se asoció a la dependencia funcional (RR:2,05;1,04-4,06). La PCR y la hemoglobina presentaban un valor significativo para predecir la mortalidad u hospitalización a 30 días posalta. Conclusiones. La ITU es un diagnóstico frecuente en pacientes mayores que consultan en SU. La dependencia funcional es el factor que mejor se asocia a eventos adversos. Los biomarcadores analizados no tienen buena capacidad predictiva. [ABSTRACT FROM AUTHOR] |
| Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
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| Items | – Name: Title Label: Title Group: Ti Data: Aspectos epidemiológicos y de manejo clínico relativos a las Infecciones del tracto urinario diagnosticadas en urgencias en pacientes mayores en España: Resultados del estudio EDEN-36. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Epidemiological and clinical management aspects related to urinary tract infections diagnosed in the emergency department in elderly patients in Spain: Results of the EDEN-36 study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Salmerón+Béliz%2C+Octavio+José%22">Salmerón Béliz, Octavio José</searchLink><relatesTo>1</relatesTo><i> octaviojose.salmeron@salud.madrid.org</i><br /><searchLink fieldCode="AR" term="%22Pérez-Fernández%2C+Elia%22">Pérez-Fernández, Elia</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Miró%2C+Òscar%22">Miró, Òscar</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Aguiló%2C+Sira%22">Aguiló, Sira</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Burillo-Putze%2C+Guillermo%22">Burillo-Putze, Guillermo</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Alquézar-Arbé%2C+Aitor%22">Alquézar-Arbé, Aitor</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Fernández-Alonso%2C+Cesáreo%22">Fernández-Alonso, Cesáreo</searchLink><relatesTo>6</relatesTo><br /><searchLink fieldCode="AR" term="%22Jacob%2C+Javier%22">Jacob, Javier</searchLink><relatesTo>7</relatesTo><br /><searchLink fieldCode="AR" term="%22Montero+Pérez%2C+Francisco+Javier%22">Montero Pérez, Francisco Javier</searchLink><relatesTo>8</relatesTo><br /><searchLink fieldCode="AR" term="%22Melcon+Villalibre%2C+Alejandro%22">Melcon Villalibre, Alejandro</searchLink><relatesTo>6</relatesTo><br /><searchLink fieldCode="AR" term="%22Cuerpo+Cardeñosa%2C+Sandra%22">Cuerpo Cardeñosa, Sandra</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Serrano+Lázaro%2C+Leticia%22">Serrano Lázaro, Leticia</searchLink><relatesTo>9</relatesTo><br /><searchLink fieldCode="AR" term="%22Caballero+Martínez%2C+María%22">Caballero Martínez, María</searchLink><relatesTo>10</relatesTo><br /><searchLink fieldCode="AR" term="%22Muñoz+Soler%2C+Esther%22">Muñoz Soler, Esther</searchLink><relatesTo>11</relatesTo><br /><searchLink fieldCode="AR" term="%22Bajo+Fernández%2C+Inmaculada%22">Bajo Fernández, Inmaculada</searchLink><relatesTo>12</relatesTo><br /><searchLink fieldCode="AR" term="%22Castuera+Gil%2C+Ana+Isabel%22">Castuera Gil, Ana Isabel</searchLink><relatesTo>13</relatesTo><br /><searchLink fieldCode="AR" term="%22Hernando+González%2C+Rocío%22">Hernando González, Rocío</searchLink><relatesTo>14</relatesTo><br /><searchLink fieldCode="AR" term="%22Carbó-Jordá%2C+Albert%22">Carbó-Jordá, Albert</searchLink><relatesTo>15</relatesTo><br /><searchLink fieldCode="AR" term="%22Cabrera+Rodrigo%2C+Irene%22">Cabrera Rodrigo, Irene</searchLink><relatesTo>16</relatesTo><br /><searchLink fieldCode="AR" term="%22Gros+Bañeres%2C+Belén%22">Gros Bañeres, Belén</searchLink><relatesTo>17</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Revista+Española+de+Quimioterapia%22">Revista Española de Quimioterapia</searchLink>. feb2025, Vol. 38 Issue 1, p28-39. 12p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22OLDER+patients%22">OLDER patients</searchLink><br /><searchLink fieldCode="DE" term="%22EMERGENCY+room+visits%22">EMERGENCY room visits</searchLink><br /><searchLink fieldCode="DE" term="%22URINARY+tract+infections%22">URINARY tract infections</searchLink><br /><searchLink fieldCode="DE" term="%22HOSPITAL+mortality%22">HOSPITAL mortality</searchLink><br /><searchLink fieldCode="DE" term="%22HOSPITAL+patients%22">HOSPITAL patients</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Objective. To estimate the incidence of urinary tract infections (UTI) in elderly patients in Spanish emergency departments (ED), the need for hospitalization, diagnostic confirmation in hospitalized patients, adverse events and the predictive capacity of several biomarkers. Methods. In this a posteriori substudy of a generic study of reasons for ED visits in elderly patients, we included patients aged =65 years seen in 52 Spanish EDs for 1 week, selecting those diagnosed with UTI. As adverse events, in-hospital and 30-day mortality and combined adverse event (death or hospitalization) at 30 days post-discharge were collected. Relative risks (RR) were calculated. The predictive capacity of 10 variables and 6 biomarkers was investigated. Results. A total of 25,375 patients were included, 1058 with UTI (annual incidence: 24.7 per 1000 inhabitants aged =65 years and year, 95%CI: 24.5-24.9). A total of 36.5% were hospitalized, and in 80% the diagnosis of UTI was confirmed at discharge. Overall 30-day mortality was 5.4% and in-hospital mortality was 3.4%. Functional dependence was associated with both events (RR:2.91;1.18-7.17 and RR:12.61;1.47-108.11, respectively), as was having a CRP greater than 100 mg/L (RR:2.24;1.17-4.30 and RR:3.21;1.37-7.51, respectively). The combined post-high event occurred in 10.6%, and was associated with functional dependence (RR:2.05;1.04-4.06). CRP and hemoglobin had significant value in predicting 30-day post-discharge mortality or hospitalization. Conclusions. UTI is a frequent diagnosis in elderly patients consulting in the ED. Functional dependence is the best factor associated with adverse events. The biomarkers analyzed do not have a good predictive capacity. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Objetivo. Estimar la incidencia de infecciones del tracto urinario (ITU) en pacientes mayores en los servicios de urgencias (SU) españoles, la necesidad de hospitalización, la confirmación diagnóstica en pacientes hospitalizados, los eventos adversos y la capacidad predictiva de varios biomarcadores. Método. En este subestudio a posteriori de un estudio genérico de motivos de consulta en urgencias de pacientes de edad avanzada, se incluyeron pacientes de =65 años atendidos en 52 SU españoles durante 1 semana seleccionándose los diagnosticados de ITU. Como eventos adversos, se recogió mortalidad intrahospitalaria y a 30 días, y evento adverso combinado (muerte u hospitalización) a 30 días posalta. Se calcularon los riesgos relativos (RR). Se investigó la capacidad predictiva de 10 variables, y de 6 biomarcadores. Resultados. Se incluyeron 25.375 pacientes, 1.058 con ITU (incidencia anual: 24.7 por 1000 habitantes =65 años y año, IC95%:24,5-24,9). El 36,5% fue hospitalizado, y en el 80% el diagnóstico de ITU constaba al alta. La mortalidad global a 30 días fue del 5,4% y la intrahospitalaria del 3,4%. La dependencia funcional se asoció a ambos eventos (RR:2,91;1,18-7,17 y RR:12,61;1,47-108,11, respectivamente), así como tener una PCR mayor de 100 mg/L (RR:2,24;1,17-4,30 y RR:3,21;1,37-7,51, respectivamente). El evento combinado posalta ocurrió en el 10,6%, y se asoció a la dependencia funcional (RR:2,05;1,04-4,06). La PCR y la hemoglobina presentaban un valor significativo para predecir la mortalidad u hospitalización a 30 días posalta. Conclusiones. La ITU es un diagnóstico frecuente en pacientes mayores que consultan en SU. La dependencia funcional es el factor que mejor se asocia a eventos adversos. Los biomarcadores analizados no tienen buena capacidad predictiva. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.37201/req/066.2024 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 12 StartPage: 28 Subjects: – SubjectFull: OLDER patients Type: general – SubjectFull: EMERGENCY room visits Type: general – SubjectFull: URINARY tract infections Type: general – SubjectFull: HOSPITAL mortality Type: general – SubjectFull: HOSPITAL patients Type: general Titles: – TitleFull: Aspectos epidemiológicos y de manejo clínico relativos a las Infecciones del tracto urinario diagnosticadas en urgencias en pacientes mayores en España: Resultados del estudio EDEN-36. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Salmerón Béliz, Octavio José – PersonEntity: Name: NameFull: Pérez-Fernández, Elia – PersonEntity: Name: NameFull: Miró, Òscar – PersonEntity: Name: NameFull: Aguiló, Sira – PersonEntity: Name: NameFull: Burillo-Putze, Guillermo – PersonEntity: Name: NameFull: Alquézar-Arbé, Aitor – PersonEntity: Name: NameFull: Fernández-Alonso, Cesáreo – PersonEntity: Name: NameFull: Jacob, Javier – PersonEntity: Name: NameFull: Montero Pérez, Francisco Javier – PersonEntity: Name: NameFull: Melcon Villalibre, Alejandro – PersonEntity: Name: NameFull: Cuerpo Cardeñosa, Sandra – PersonEntity: Name: NameFull: Serrano Lázaro, Leticia – PersonEntity: Name: NameFull: Caballero Martínez, María – PersonEntity: Name: NameFull: Muñoz Soler, Esther – PersonEntity: Name: NameFull: Bajo Fernández, Inmaculada – PersonEntity: Name: NameFull: Castuera Gil, Ana Isabel – PersonEntity: Name: NameFull: Hernando González, Rocío – PersonEntity: Name: NameFull: Carbó-Jordá, Albert – PersonEntity: Name: NameFull: Cabrera Rodrigo, Irene – PersonEntity: Name: NameFull: Gros Bañeres, Belén IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: feb2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 02143429 Numbering: – Type: volume Value: 38 – Type: issue Value: 1 Titles: – TitleFull: Revista Española de Quimioterapia Type: main |
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