Relación entre los niveles de albúmina con la presencia y desarrollo de fragilidad en países de bajos a medianos ingresos: Análisis del estudio internacional de movilidad en envejecimiento (IMIAS).
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| Title: | Relación entre los niveles de albúmina con la presencia y desarrollo de fragilidad en países de bajos a medianos ingresos: Análisis del estudio internacional de movilidad en envejecimiento (IMIAS). |
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| Alternate Title: | The relationship between albumin levels and the presence and progression of frailty in low to middle-income countries: An analysis of the International Mobility in Aging Study (IMIAS). |
| Authors: | ALEJANDRO GÓMEZ-CASTRILLÓN, DIEGO1 d.alejandro.gomez019@gmail.com, PINEDA-ARREDONDO, EDISON1, MARÍA CANO-MÉNDEZ, LAURA1, GÓMEZ-MONTES, FERNANDO1, OLIVEIRA-GUERRA, RICARDO2, MCLEAN-PIRKLE, CATHERINE3 |
| Source: | Acta Medica Colombiana. abr2025, Vol. 50 Issue 2, p1-8. 8p. |
| Subjects: | LOGISTIC regression analysis, OLDER people, GRIP strength, PHYSICAL mobility, MIDDLE-income countries |
| Abstract (English): | Introduction: frailty is a geriatric syndrome with multiple causes and contributing factors, which increases vulnerability to various health outcomes like disability and death. Low albumin is considered to be a potential indicator of frailty; however, the evidence is controversial. This study seeks to relate low albumin to the presence and progression of frailty in older adults in low and middle-income countries. Design and analysis: this was a longitudinal observational study using data from the International Mobility in Aging Study (IMIAS). Data was analyzed from 837 adults 65 to 74 years of age from Tirana (Albania), Natal (Brazil) and Manizales (Colombia), who were followed from 2012 to 2016. The analysis included sociodemographic, anthropometric, physical health, mental health and mobility variables Results: a multivariate logistic regression analysis showed that hypoalbuminemia (<4 gr/dL) (RR= 2.51, p= 0.021), poor grip strength (RR= 2.67, p= 0.001), a score < 8 on the Short Physical Performance Battery (SPPB) (RR= 4.641, p= 0.000) and a mobility disability (RR= 2.89, p=0.004) were independently related to a higher risk of developing frailty in four years. Conclusions: low albumin in older adults is an independent risk factor for the developing frailty. This information is relevant and could contribute to predicting and treating frailty in older adults which could, in turn, prevent complications and lower the medical costs related to its care. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Introducción: la fragilidad es un síndrome geriátrico con múltiples causas y factores contribuyentes, el cual aumenta la vulnerabilidad a diversos desenlaces en salud, como discapacidad y muerte. La albúmina baja es considerada como un potencial indicador de fragilidad; sin embargo, la evidencia es controversial. Este estudio busca relacionar la albúmina baja con la presencia y con el desarrollo de fragilidad en personas mayores de países de bajos a medianos ingresos. Diseño y análisis: estudio observacional longitudinal utilizando datos del Estudio Internacional de Movilidad en Envejecimiento (IMIAS). Se analizaron datos de 837 adultos entre 65 y 74 años con seguimiento entre el 2012 y 2016 de Tirana (Albania); Natal (Brasil) y Manizales (Colombia). En el análisis se incluyeron variables sociodemográficas, antropométricas, salud física, salud mental y de movilidad. Resultados: un análisis multivariado de regresión logística mostró que la hipoalbuminemia (<4 gr/dL) (RR= 2.51, p= 0.021), baja fuerza de agarre (RR= 2.67, p= 0.001), un Short Physical Performance Battery (SPPB) < 8 puntos (RR= 4.641, p= 0.000) y un estado de discapacidad para la movilidad (RR= 2.89, p=0.004), se asocian de forma independiente con un mayor riesgo de desarrollo de fragilidad en cuatro años. Conclusiones: la albúmina baja en las personas mayores es un factor de riesgo independiente para el desarrollo de fragilidad. Esta información es relevante y puede contribuir a predecir y a intervenir la fragilidad en las personas mayores, lo que a su vez podría evitar complicaciones y disminuir los costos médicos relacionados con su atención. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Medica Colombiana is the property of Acta Medica Colombiana and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 185270804 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Relación entre los niveles de albúmina con la presencia y desarrollo de fragilidad en países de bajos a medianos ingresos: Análisis del estudio internacional de movilidad en envejecimiento (IMIAS). – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: The relationship between albumin levels and the presence and progression of frailty in low to middle-income countries: An analysis of the International Mobility in Aging Study (IMIAS). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22ALEJANDRO+GÓMEZ-CASTRILLÓN%2C+DIEGO%22">ALEJANDRO GÓMEZ-CASTRILLÓN, DIEGO</searchLink><relatesTo>1</relatesTo><i> d.alejandro.gomez019@gmail.com</i><br /><searchLink fieldCode="AR" term="%22PINEDA-ARREDONDO%2C+EDISON%22">PINEDA-ARREDONDO, EDISON</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22MARÍA+CANO-MÉNDEZ%2C+LAURA%22">MARÍA CANO-MÉNDEZ, LAURA</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22GÓMEZ-MONTES%2C+FERNANDO%22">GÓMEZ-MONTES, FERNANDO</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22OLIVEIRA-GUERRA%2C+RICARDO%22">OLIVEIRA-GUERRA, RICARDO</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22MCLEAN-PIRKLE%2C+CATHERINE%22">MCLEAN-PIRKLE, CATHERINE</searchLink><relatesTo>3</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Acta+Medica+Colombiana%22">Acta Medica Colombiana</searchLink>. abr2025, Vol. 50 Issue 2, p1-8. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22LOGISTIC+regression+analysis%22">LOGISTIC regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22OLDER+people%22">OLDER people</searchLink><br /><searchLink fieldCode="DE" term="%22GRIP+strength%22">GRIP strength</searchLink><br /><searchLink fieldCode="DE" term="%22PHYSICAL+mobility%22">PHYSICAL mobility</searchLink><br /><searchLink fieldCode="DE" term="%22MIDDLE-income+countries%22">MIDDLE-income countries</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Introduction: frailty is a geriatric syndrome with multiple causes and contributing factors, which increases vulnerability to various health outcomes like disability and death. Low albumin is considered to be a potential indicator of frailty; however, the evidence is controversial. This study seeks to relate low albumin to the presence and progression of frailty in older adults in low and middle-income countries. Design and analysis: this was a longitudinal observational study using data from the International Mobility in Aging Study (IMIAS). Data was analyzed from 837 adults 65 to 74 years of age from Tirana (Albania), Natal (Brazil) and Manizales (Colombia), who were followed from 2012 to 2016. The analysis included sociodemographic, anthropometric, physical health, mental health and mobility variables Results: a multivariate logistic regression analysis showed that hypoalbuminemia (<4 gr/dL) (RR= 2.51, p= 0.021), poor grip strength (RR= 2.67, p= 0.001), a score < 8 on the Short Physical Performance Battery (SPPB) (RR= 4.641, p= 0.000) and a mobility disability (RR= 2.89, p=0.004) were independently related to a higher risk of developing frailty in four years. Conclusions: low albumin in older adults is an independent risk factor for the developing frailty. This information is relevant and could contribute to predicting and treating frailty in older adults which could, in turn, prevent complications and lower the medical costs related to its care. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Introducción: la fragilidad es un síndrome geriátrico con múltiples causas y factores contribuyentes, el cual aumenta la vulnerabilidad a diversos desenlaces en salud, como discapacidad y muerte. La albúmina baja es considerada como un potencial indicador de fragilidad; sin embargo, la evidencia es controversial. Este estudio busca relacionar la albúmina baja con la presencia y con el desarrollo de fragilidad en personas mayores de países de bajos a medianos ingresos. Diseño y análisis: estudio observacional longitudinal utilizando datos del Estudio Internacional de Movilidad en Envejecimiento (IMIAS). Se analizaron datos de 837 adultos entre 65 y 74 años con seguimiento entre el 2012 y 2016 de Tirana (Albania); Natal (Brasil) y Manizales (Colombia). En el análisis se incluyeron variables sociodemográficas, antropométricas, salud física, salud mental y de movilidad. Resultados: un análisis multivariado de regresión logística mostró que la hipoalbuminemia (<4 gr/dL) (RR= 2.51, p= 0.021), baja fuerza de agarre (RR= 2.67, p= 0.001), un Short Physical Performance Battery (SPPB) < 8 puntos (RR= 4.641, p= 0.000) y un estado de discapacidad para la movilidad (RR= 2.89, p=0.004), se asocian de forma independiente con un mayor riesgo de desarrollo de fragilidad en cuatro años. Conclusiones: la albúmina baja en las personas mayores es un factor de riesgo independiente para el desarrollo de fragilidad. Esta información es relevante y puede contribuir a predecir y a intervenir la fragilidad en las personas mayores, lo que a su vez podría evitar complicaciones y disminuir los costos médicos relacionados con su atención. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Acta Medica Colombiana is the property of Acta Medica Colombiana and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.36104/amc.2025.3306 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 8 StartPage: 1 Subjects: – SubjectFull: LOGISTIC regression analysis Type: general – SubjectFull: OLDER people Type: general – SubjectFull: GRIP strength Type: general – SubjectFull: PHYSICAL mobility Type: general – SubjectFull: MIDDLE-income countries Type: general Titles: – TitleFull: Relación entre los niveles de albúmina con la presencia y desarrollo de fragilidad en países de bajos a medianos ingresos: Análisis del estudio internacional de movilidad en envejecimiento (IMIAS). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: ALEJANDRO GÓMEZ-CASTRILLÓN, DIEGO – PersonEntity: Name: NameFull: PINEDA-ARREDONDO, EDISON – PersonEntity: Name: NameFull: MARÍA CANO-MÉNDEZ, LAURA – PersonEntity: Name: NameFull: GÓMEZ-MONTES, FERNANDO – PersonEntity: Name: NameFull: OLIVEIRA-GUERRA, RICARDO – PersonEntity: Name: NameFull: MCLEAN-PIRKLE, CATHERINE IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: abr2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 01202448 Numbering: – Type: volume Value: 50 – Type: issue Value: 2 Titles: – TitleFull: Acta Medica Colombiana Type: main |
| ResultId | 1 |
