NEUROPSYCHOLOGICAL PROFILE ASSOCIATED WITH BORDERLINE PERSONALITY DISORDER: A CLINICAL STUDY IN FEMALES.

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Title: NEUROPSYCHOLOGICAL PROFILE ASSOCIATED WITH BORDERLINE PERSONALITY DISORDER: A CLINICAL STUDY IN FEMALES.
Alternate Title: PERFIL NEUROPSICOLÓGICO ASOCIADO AL TRASTORNO LÍMITE DE LA PERSONALIDAD: UN ESTUDIO CLÍNICO EN MUJERES.
PERFIL NEUROPSICOLÓGICO ASSOCIADO AO TRANSTORNO DE PERSONALIDADE LIMÍTROFE: UM ESTUDO CLÍNICO EM MULHERES.
Authors: Laffite, Horus1,2 hlafcab@gmail.com, Antonio Díaz-Garrido, Juan1,2,3, Rodríguez-Otero, Fernando2, Francisca MartínezHuidobro, María2, Roncancio-Medina, Tatiana3, Alonso Sosa, Raquel2, Luis Hernández-Fleta, José1,2
Source: Panamerican Journal of Neuropsychology / Cuadernos de Neuropsicología. ene-abr2025, Vol. 19 Issue 1, p73-87. 15p.
Subjects: EXECUTIVE function, COGNITIVE processing speed, COGNITION, TRAIL Making Test, RESPONSE inhibition, BORDERLINE personality disorder, FLUENCY (Language learning)
Abstract (English): Numerous studies have identified neurocognitive impairments in borderline personality disorder (BPD), particularly in executive functions (EF). However, findings have been inconsistent. This study aimed to evaluate the neuropsychological functioning of a clinical sample of women diagnosed with BPD receiving outpatient treatment. A total of 71 women (M(SD) = 28.5(6.5) years) were assessed using standardized neuropsychological tests measuring attention, memory, and EF, including the Trail Making Test, Stroop Test, Symbol Digit Modalities Test, Digit Span, Verbal Fluency, and Rey Auditory Verbal Learning Test. The results indicate widespread impairments in attention, processing speed, cognitive flexibility, and inhibitory control, while verbal fluency and working memory remained within normative limits. Learning and memory performance exhibited a progressive decline over time compared to normative data. These findings support the hypothesis that young adult women with BPD experience broad neuropsychological impairments, with relative preservation in some cognitive domains. The observed decline in learning capacity underscores the need for tailored neuropsychological rehabilitation programs and psychotherapeutic adaptations to mitigate cognitive difficulties in this population. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Numerosos estudios han identificado deterioro neurocognitivo en el trastorno límite de la personalidad (TLP), particularmente en las funciones ejecutivas (FE). Sin embargo, los hallazgos han sido inconsistentes. Este estudio tuvo como objetivo analizar el funcionamiento neuropsicológico en una muestra clínica de mujeres con diagnóstico de TLP en tratamiento ambulatorio. Se evaluó a 71 mujeres (M(DE) = 28.5(6.5) años) mediante pruebas neuropsicológicas estandarizadas para medir atención, memoria y FE, utilizando el Trail Making Test, Stroop Test, Symbol Digit Modalities Test, Span de Dígitos, Fluencia Verbal y Rey Auditory Verbal Learning Test. Los resultados evidenciaron dificultades generalizadas en atención, velocidad de procesamiento, flexibilidad cognitiva y control inhibitorio, mientras que la fluidez verbal y la memoria de trabajo se mantuvieron dentro de los límites normativos. El rendimiento en aprendizaje y memoria mostró un deterioro progresivo en comparación con los datos normativos. Estos hallazgos respaldan la hipótesis de que las mujeres jóvenes con TLP presentan alteraciones neuropsicológicas extendidas, con una relativa preservación en algunos dominios cognitivos. El deterioro observado en la capacidad de aprendizaje subraya la necesidad de implementar programas específicos de rehabilitación neuropsicológica y adaptar las intervenciones psicoterapéuticas para mitigar las dificultades cognitivas en esta población. [ABSTRACT FROM AUTHOR]
Abstract (Portuguese): Diversos estudos identificaram comprometimento neurocognitivo no transtorno de personalidade limítrofe (TPB), principalmente nas funções executivas (FE). Entretanto, os resultados têm sido inconsistentes. O objetivo deste estudo foi analisar o funcionamento neuropsicológico em uma amostra clínica de mulheres com diagnóstico de TPB em tratamento ambulatorial. Setenta e uma mulheres (M(SD) = 28,5(6,5) anos) foram avaliadas por meio de testes neuropsicológicos padronizados para medir a atenção, a memória e as FE, usando o Trail Making Test, o Stroop Test, o Symbol Digit Modalities Test, o Digit Span, a Fluência Verbal e o Rey Auditory Verbal Learning Test. Os resultados mostraram dificuldades generalizadas na atenção, velocidade de processamento, flexibilidade cognitiva e controle inibitório, enquanto a fluência verbal e a memória de trabalho permaneceram dentro dos limites normativos. O desempenho em aprendizado e memória apresentou deterioração progressiva em comparação com os dados normativos. Esses achados apóiam a hipótese de que as mulheres jovens com TPB apresentam deficiências neuropsicológicas generalizadas, com relativa preservação em alguns domínios cognitivos. O prejuízo observado na capacidade de aprendizado ressalta a necessidade de implementar programas específicos de reabilitação neuropsicológica e adaptar intervenções psicoterapêuticas para atenuar as dificuldades cognitivas nessa população. [ABSTRACT FROM AUTHOR]
Copyright of Panamerican Journal of Neuropsychology / Cuadernos de Neuropsicología is the property of Cuadernos de Neuropsicologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: NEUROPSYCHOLOGICAL PROFILE ASSOCIATED WITH BORDERLINE PERSONALITY DISORDER: A CLINICAL STUDY IN FEMALES.
– Name: TitleAlt
  Label: Alternate Title
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  Data: PERFIL NEUROPSICOLÓGICO ASOCIADO AL TRASTORNO LÍMITE DE LA PERSONALIDAD: UN ESTUDIO CLÍNICO EN MUJERES.<br />PERFIL NEUROPSICOLÓGICO ASSOCIADO AO TRANSTORNO DE PERSONALIDADE LIMÍTROFE: UM ESTUDO CLÍNICO EM MULHERES.
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  Data: <searchLink fieldCode="AR" term="%22Laffite%2C+Horus%22">Laffite, Horus</searchLink><relatesTo>1,2</relatesTo><i> hlafcab@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Antonio+Díaz-Garrido%2C+Juan%22">Antonio Díaz-Garrido, Juan</searchLink><relatesTo>1,2,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Rodríguez-Otero%2C+Fernando%22">Rodríguez-Otero, Fernando</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Francisca+MartínezHuidobro%2C+María%22">Francisca MartínezHuidobro, María</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Roncancio-Medina%2C+Tatiana%22">Roncancio-Medina, Tatiana</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Alonso+Sosa%2C+Raquel%22">Alonso Sosa, Raquel</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Luis+Hernández-Fleta%2C+José%22">Luis Hernández-Fleta, José</searchLink><relatesTo>1,2</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Panamerican+Journal+of+Neuropsychology+%2F+Cuadernos+de+Neuropsicología%22">Panamerican Journal of Neuropsychology / Cuadernos de Neuropsicología</searchLink>. ene-abr2025, Vol. 19 Issue 1, p73-87. 15p.
– Name: Subject
  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22EXECUTIVE+function%22">EXECUTIVE function</searchLink><br /><searchLink fieldCode="DE" term="%22COGNITIVE+processing+speed%22">COGNITIVE processing speed</searchLink><br /><searchLink fieldCode="DE" term="%22COGNITION%22">COGNITION</searchLink><br /><searchLink fieldCode="DE" term="%22TRAIL+Making+Test%22">TRAIL Making Test</searchLink><br /><searchLink fieldCode="DE" term="%22RESPONSE+inhibition%22">RESPONSE inhibition</searchLink><br /><searchLink fieldCode="DE" term="%22BORDERLINE+personality+disorder%22">BORDERLINE personality disorder</searchLink><br /><searchLink fieldCode="DE" term="%22FLUENCY+%28Language+learning%29%22">FLUENCY (Language learning)</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Numerous studies have identified neurocognitive impairments in borderline personality disorder (BPD), particularly in executive functions (EF). However, findings have been inconsistent. This study aimed to evaluate the neuropsychological functioning of a clinical sample of women diagnosed with BPD receiving outpatient treatment. A total of 71 women (M(SD) = 28.5(6.5) years) were assessed using standardized neuropsychological tests measuring attention, memory, and EF, including the Trail Making Test, Stroop Test, Symbol Digit Modalities Test, Digit Span, Verbal Fluency, and Rey Auditory Verbal Learning Test. The results indicate widespread impairments in attention, processing speed, cognitive flexibility, and inhibitory control, while verbal fluency and working memory remained within normative limits. Learning and memory performance exhibited a progressive decline over time compared to normative data. These findings support the hypothesis that young adult women with BPD experience broad neuropsychological impairments, with relative preservation in some cognitive domains. The observed decline in learning capacity underscores the need for tailored neuropsychological rehabilitation programs and psychotherapeutic adaptations to mitigate cognitive difficulties in this population. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Numerosos estudios han identificado deterioro neurocognitivo en el trastorno límite de la personalidad (TLP), particularmente en las funciones ejecutivas (FE). Sin embargo, los hallazgos han sido inconsistentes. Este estudio tuvo como objetivo analizar el funcionamiento neuropsicológico en una muestra clínica de mujeres con diagnóstico de TLP en tratamiento ambulatorio. Se evaluó a 71 mujeres (M(DE) = 28.5(6.5) años) mediante pruebas neuropsicológicas estandarizadas para medir atención, memoria y FE, utilizando el Trail Making Test, Stroop Test, Symbol Digit Modalities Test, Span de Dígitos, Fluencia Verbal y Rey Auditory Verbal Learning Test. Los resultados evidenciaron dificultades generalizadas en atención, velocidad de procesamiento, flexibilidad cognitiva y control inhibitorio, mientras que la fluidez verbal y la memoria de trabajo se mantuvieron dentro de los límites normativos. El rendimiento en aprendizaje y memoria mostró un deterioro progresivo en comparación con los datos normativos. Estos hallazgos respaldan la hipótesis de que las mujeres jóvenes con TLP presentan alteraciones neuropsicológicas extendidas, con una relativa preservación en algunos dominios cognitivos. El deterioro observado en la capacidad de aprendizaje subraya la necesidad de implementar programas específicos de rehabilitación neuropsicológica y adaptar las intervenciones psicoterapéuticas para mitigar las dificultades cognitivas en esta población. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Portuguese)
  Group: Ab
  Data: Diversos estudos identificaram comprometimento neurocognitivo no transtorno de personalidade limítrofe (TPB), principalmente nas funções executivas (FE). Entretanto, os resultados têm sido inconsistentes. O objetivo deste estudo foi analisar o funcionamento neuropsicológico em uma amostra clínica de mulheres com diagnóstico de TPB em tratamento ambulatorial. Setenta e uma mulheres (M(SD) = 28,5(6,5) anos) foram avaliadas por meio de testes neuropsicológicos padronizados para medir a atenção, a memória e as FE, usando o Trail Making Test, o Stroop Test, o Symbol Digit Modalities Test, o Digit Span, a Fluência Verbal e o Rey Auditory Verbal Learning Test. Os resultados mostraram dificuldades generalizadas na atenção, velocidade de processamento, flexibilidade cognitiva e controle inibitório, enquanto a fluência verbal e a memória de trabalho permaneceram dentro dos limites normativos. O desempenho em aprendizado e memória apresentou deterioração progressiva em comparação com os dados normativos. Esses achados apóiam a hipótese de que as mulheres jovens com TPB apresentam deficiências neuropsicológicas generalizadas, com relativa preservação em alguns domínios cognitivos. O prejuízo observado na capacidade de aprendizado ressalta a necessidade de implementar programas específicos de reabilitação neuropsicológica e adaptar intervenções psicoterapêuticas para atenuar as dificuldades cognitivas nessa população. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Panamerican Journal of Neuropsychology / Cuadernos de Neuropsicología is the property of Cuadernos de Neuropsicologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Text: English
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      – SubjectFull: EXECUTIVE function
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      – SubjectFull: COGNITIVE processing speed
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      – SubjectFull: COGNITION
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      – SubjectFull: TRAIL Making Test
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      – TitleFull: NEUROPSYCHOLOGICAL PROFILE ASSOCIATED WITH BORDERLINE PERSONALITY DISORDER: A CLINICAL STUDY IN FEMALES.
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