Clinical Effect of Traditional Chinese Medicine (An Shen Jiao Tai Yi Zhi Decoction) on Sleep Disorders in Patients With Parkinson's Disease.
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| Title: | Clinical Effect of Traditional Chinese Medicine (An Shen Jiao Tai Yi Zhi Decoction) on Sleep Disorders in Patients With Parkinson's Disease. |
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| Authors: | Lidan Pu1 18731170088@163.com, Xuefei Liu1, Chaoyi Fang2, Zhiwei Su3, Shiyun Sheng4, Haolei Yang5 |
| Source: | Actas Espanolas de Psiquiatria. 2025, Vol. 53 Issue 3, p535-545. 11p. |
| Subjects: | CHINESE medicine, PARKINSON'S disease, PROPENSITY score matching, EPWORTH Sleepiness Scale, SLEEP disorders |
| Abstract: | Background: Current research on An Shen Jiao Tai Yi Zhi decoction remains limited, highlighting the need for further investigation to validate its therapeutic efficacy and elucidate its underlying mechanisms of action. A study was conducted to evaluate the effects of An Shen Jiao Tai Yi Zhi decoction on sleep disorders in patients with Parkinson's disease. Methods: The study population comprised 85 patients diagnosed with Parkinson's disease and sleep disorders at the Department of Encephalopathy of Hebei Provincial-Hospital of Traditional ChineseMedicine, between January 2021 and December 2023. In accordance with different treatment methods, they were divided into the Western medicine group (n = 45, conventional Western medicine treatment plus pramipexole hydrochloride) and the traditional Chinese medicine group (n = 40, An Shen Jiao Tai Yi Zhi decoction based on the Western medicine group). To minimize selection bias, propensity score matching (PSM) was employed with a 1:1 ratio, yielding 20 cases in the traditional Chinese medicine group and 20 cases in the Western medicine group. Clinical data, total effective rates, Epworth Sleepiness Scale (ESS) scores, sleep architecture parameters, homocysteine levels, interleukin-1β concentration, and adverse reactions were collected for all participants. Baseline characteristics were balanced between the two groups through PSM. The data were analyzed using t-test, chi-square test, and analysis of variance. Results: PSM matching was performed in a ratio of 1:1, and a total of 40 patients were divided into two groups. No significant differences in clinical characteristics were observed between the groups. The total effective rate of the traditional Chinese medicine group was higher than that of the Western medicine group (p < 0.05). Before the intervention, no differences in ESS score, sleep architecture, and related factors were found among the two groups (p > 0.05). After 14 days of intervention, the traditional Chinese medicine group exhibited significantly greater improvements across all measured indicators compared to the Western medicine group (p < 0.05). Notably, there were no significant differences in the incidence of adverse reactions between the two groups (p > 0.05). Conclusions: An Shen Jiao Tai Yi Zhi decoction demonstrates significant therapeutic efficacy, exhibiting anti-inflammatory properties and promoting changes in sleep architecture, with minimal adverse effects. [ABSTRACT FROM AUTHOR] |
| Copyright of Actas Espanolas de Psiquiatria is the property of Maria Lopez-Ibor and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 185791987 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Clinical Effect of Traditional Chinese Medicine (An Shen Jiao Tai Yi Zhi Decoction) on Sleep Disorders in Patients With Parkinson's Disease. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Lidan+Pu%22">Lidan Pu</searchLink><relatesTo>1</relatesTo><i> 18731170088@163.com</i><br /><searchLink fieldCode="AR" term="%22Xuefei+Liu%22">Xuefei Liu</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Chaoyi+Fang%22">Chaoyi Fang</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhiwei+Su%22">Zhiwei Su</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Shiyun+Sheng%22">Shiyun Sheng</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Haolei+Yang%22">Haolei Yang</searchLink><relatesTo>5</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Actas+Espanolas+de+Psiquiatria%22">Actas Espanolas de Psiquiatria</searchLink>. 2025, Vol. 53 Issue 3, p535-545. 11p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22CHINESE+medicine%22">CHINESE medicine</searchLink><br /><searchLink fieldCode="DE" term="%22PARKINSON'S+disease%22">PARKINSON'S disease</searchLink><br /><searchLink fieldCode="DE" term="%22PROPENSITY+score+matching%22">PROPENSITY score matching</searchLink><br /><searchLink fieldCode="DE" term="%22EPWORTH+Sleepiness+Scale%22">EPWORTH Sleepiness Scale</searchLink><br /><searchLink fieldCode="DE" term="%22SLEEP+disorders%22">SLEEP disorders</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background: Current research on An Shen Jiao Tai Yi Zhi decoction remains limited, highlighting the need for further investigation to validate its therapeutic efficacy and elucidate its underlying mechanisms of action. A study was conducted to evaluate the effects of An Shen Jiao Tai Yi Zhi decoction on sleep disorders in patients with Parkinson's disease. Methods: The study population comprised 85 patients diagnosed with Parkinson's disease and sleep disorders at the Department of Encephalopathy of Hebei Provincial-Hospital of Traditional ChineseMedicine, between January 2021 and December 2023. In accordance with different treatment methods, they were divided into the Western medicine group (n = 45, conventional Western medicine treatment plus pramipexole hydrochloride) and the traditional Chinese medicine group (n = 40, An Shen Jiao Tai Yi Zhi decoction based on the Western medicine group). To minimize selection bias, propensity score matching (PSM) was employed with a 1:1 ratio, yielding 20 cases in the traditional Chinese medicine group and 20 cases in the Western medicine group. Clinical data, total effective rates, Epworth Sleepiness Scale (ESS) scores, sleep architecture parameters, homocysteine levels, interleukin-1β concentration, and adverse reactions were collected for all participants. Baseline characteristics were balanced between the two groups through PSM. The data were analyzed using t-test, chi-square test, and analysis of variance. Results: PSM matching was performed in a ratio of 1:1, and a total of 40 patients were divided into two groups. No significant differences in clinical characteristics were observed between the groups. The total effective rate of the traditional Chinese medicine group was higher than that of the Western medicine group (p < 0.05). Before the intervention, no differences in ESS score, sleep architecture, and related factors were found among the two groups (p > 0.05). After 14 days of intervention, the traditional Chinese medicine group exhibited significantly greater improvements across all measured indicators compared to the Western medicine group (p < 0.05). Notably, there were no significant differences in the incidence of adverse reactions between the two groups (p > 0.05). Conclusions: An Shen Jiao Tai Yi Zhi decoction demonstrates significant therapeutic efficacy, exhibiting anti-inflammatory properties and promoting changes in sleep architecture, with minimal adverse effects. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Actas Espanolas de Psiquiatria is the property of Maria Lopez-Ibor and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.62641/aep.v53i3.1809 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 11 StartPage: 535 Subjects: – SubjectFull: CHINESE medicine Type: general – SubjectFull: PARKINSON'S disease Type: general – SubjectFull: PROPENSITY score matching Type: general – SubjectFull: EPWORTH Sleepiness Scale Type: general – SubjectFull: SLEEP disorders Type: general Titles: – TitleFull: Clinical Effect of Traditional Chinese Medicine (An Shen Jiao Tai Yi Zhi Decoction) on Sleep Disorders in Patients With Parkinson's Disease. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lidan Pu – PersonEntity: Name: NameFull: Xuefei Liu – PersonEntity: Name: NameFull: Chaoyi Fang – PersonEntity: Name: NameFull: Zhiwei Su – PersonEntity: Name: NameFull: Shiyun Sheng – PersonEntity: Name: NameFull: Haolei Yang IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 11399287 Numbering: – Type: volume Value: 53 – Type: issue Value: 3 Titles: – TitleFull: Actas Espanolas de Psiquiatria Type: main |
| ResultId | 1 |
