Deficiencia de Vitamina D en adolescentes hospitalizados con trastornos de salud mental.

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Title: Deficiencia de Vitamina D en adolescentes hospitalizados con trastornos de salud mental.
Alternate Title: Vitamin D deficiency in hospitalized adolescents with mental health disorders.
Authors: Lozano Adriasola, María Ignacia1, Pacheco Acosta, Johanna Carolina2, Flores Cano, Juan Carlos1, Galaz, Gonzalo Valenzuela1, Soto, Paula Bravo2, Mejía Rojas, Cindy Paola2, Correa Venegas, María Loreto1 mlcorrea@uc.cl
Source: Andes Pediatrica. Jun2025, Vol. 96 Issue 3, p359-366. 8p.
Subjects: VITAMIN D deficiency, MENTAL illness, HOSPITAL patients, TEENAGERS, NUTRITIONAL status, OVERWEIGHT persons, SEASONAL physiological variations
Abstract (English): Mental health disorders (MHD) are a growing problem in adolescents. There is evidence that vitamin D (VD) deficiency is associated with MHD. Objective: To evaluate VD deficiency in adolescents with MHD hospitalized in the Adolescent Hospital Unit (UHA), and to explore associated factors. Patients and Method: Observational, analytical, cross-sectional study. All adolescents aged between 10 and 17 years, with MHD, admitted to the UHA, and in whom 25-OH VD measurement was performed were included. The association between serum 25-OH VD concentration and variables of interest (sociodemographic, comorbidity) was evaluated in a multivariate model, including nutritional status (WHO 2007), season, mood disorder, type of diet, age, and sex, among others. Results: 164 adolescents were included. VD deficiency was 76.6%, and 44.8% had severe deficiency. The VD deficiency was 90.9% in overweight adolescents and 82.2% in obese adolescents. The adjusted mean 25-OH VD levels were 23.3 ng/ml (95% confidence interval [CI]: 16.7-30.0) in deficiency malnutrition, and 14.2 ng/ml (95%CI: 10.1-18.3) in overweight (p< 0.01); and 21.1 ng/ml (95% CI: 15.7-26.4) in December-February versus 16.2 ng/ml (95% CI: 12.1- 20.2) in June-August (p= 0.02). There were no differences according to mood disorder. Conclusions: Hospitalized adolescents with MHD have a high VD deficiency. A statistically significant association was found between VD levels and the variables of nutritional status and season. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Los trastornos de salud mental (TSM) constituyen un problema creciente en los adolescentes. Existe evidencia que el déficit de vitamina D (VD) está asociado a TSM. Objetivo: Evaluar la deficiencia de VD en adolescentes con TSM hospitalizados en una Unidad Hospitalaria de Adolescencia (UHA), y explorar factores asociados. Pacientes y Método: Estudio observacional, analítico, de corte transversal. Se incluyeron todos los adolescentes entre 10 a 17 años, con TSM, ingresados a la UHA entre el 2019 y 2021, en quienes se realizó medición de 25 hidroxi-vitamina D (25-OH VD). Se evaluó la asociación entre concentración sérica 25-OH VD y variables de interés (sociodemográficas, comorbilidad) en un modelo multivariado, incluyendo estado nutricional (OMS 2007), estación del año, trastorno del ánimo, tipo de alimentación, edad y sexo, entre otras. Resultados: Se incluyeron 164 adolescentes. La deficiencia de VD fue 76,6% (44,8% deficiencia severa). El déficit de VD fue de 90,9% en adolescentes con sobrepeso y 82,2% con obesidad. El promedio ajustado de 25-OH VD fue de 23,3 ng/ml (IC 95%: 16,7-30,0) en malnutrición por déficit, versus 14,2 ng/ml (IC 95%: 10,1-18,3) en sobrepeso (p< 0,01); y 21,1 mg/ml (IC 95%: 15,7-26,4) en los meses de diciembre-febrero versus 16,2 ng/ml (IC 95%: 12,1-20,2) en junio-agosto (p= 0,02). No hubo diferencias según trastorno de ánimo. Conclusiones: Los adolescentes con TSM hospitalizados tienen un alto déficit de VD. Se encontró asociación estadísticamente significativa entre niveles de VD y las variables estado nutricional y estación del año. [ABSTRACT FROM AUTHOR]
Copyright of Andes Pediatrica is the property of Revista Chilena de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Deficiencia de Vitamina D en adolescentes hospitalizados con trastornos de salud mental.
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  Data: Vitamin D deficiency in hospitalized adolescents with mental health disorders.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lozano+Adriasola%2C+Mar&#237;a+Ignacia%22&quot;&gt;Lozano Adriasola, Mar&#237;a Ignacia&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Pacheco+Acosta%2C+Johanna+Carolina%22&quot;&gt;Pacheco Acosta, Johanna Carolina&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Flores+Cano%2C+Juan+Carlos%22&quot;&gt;Flores Cano, Juan Carlos&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Galaz%2C+Gonzalo+Valenzuela%22&quot;&gt;Galaz, Gonzalo Valenzuela&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Soto%2C+Paula+Bravo%22&quot;&gt;Soto, Paula Bravo&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Mej&#237;a+Rojas%2C+Cindy+Paola%22&quot;&gt;Mej&#237;a Rojas, Cindy Paola&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Correa+Venegas%2C+Mar&#237;a+Loreto%22&quot;&gt;Correa Venegas, Mar&#237;a Loreto&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt; mlcorrea@uc.cl&lt;/i&gt;
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Andes+Pediatrica%22&quot;&gt;Andes Pediatrica&lt;/searchLink&gt;. Jun2025, Vol. 96 Issue 3, p359-366. 8p.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22VITAMIN+D+deficiency%22&quot;&gt;VITAMIN D deficiency&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22MENTAL+illness%22&quot;&gt;MENTAL illness&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22HOSPITAL+patients%22&quot;&gt;HOSPITAL patients&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22TEENAGERS%22&quot;&gt;TEENAGERS&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22NUTRITIONAL+status%22&quot;&gt;NUTRITIONAL status&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22OVERWEIGHT+persons%22&quot;&gt;OVERWEIGHT persons&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22SEASONAL+physiological+variations%22&quot;&gt;SEASONAL physiological variations&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Mental health disorders (MHD) are a growing problem in adolescents. There is evidence that vitamin D (VD) deficiency is associated with MHD. Objective: To evaluate VD deficiency in adolescents with MHD hospitalized in the Adolescent Hospital Unit (UHA), and to explore associated factors. Patients and Method: Observational, analytical, cross-sectional study. All adolescents aged between 10 and 17 years, with MHD, admitted to the UHA, and in whom 25-OH VD measurement was performed were included. The association between serum 25-OH VD concentration and variables of interest (sociodemographic, comorbidity) was evaluated in a multivariate model, including nutritional status (WHO 2007), season, mood disorder, type of diet, age, and sex, among others. Results: 164 adolescents were included. VD deficiency was 76.6%, and 44.8% had severe deficiency. The VD deficiency was 90.9% in overweight adolescents and 82.2% in obese adolescents. The adjusted mean 25-OH VD levels were 23.3 ng/ml (95% confidence interval [CI]: 16.7-30.0) in deficiency malnutrition, and 14.2 ng/ml (95%CI: 10.1-18.3) in overweight (p&lt; 0.01); and 21.1 ng/ml (95% CI: 15.7-26.4) in December-February versus 16.2 ng/ml (95% CI: 12.1- 20.2) in June-August (p= 0.02). There were no differences according to mood disorder. Conclusions: Hospitalized adolescents with MHD have a high VD deficiency. A statistically significant association was found between VD levels and the variables of nutritional status and season. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Los trastornos de salud mental (TSM) constituyen un problema creciente en los adolescentes. Existe evidencia que el d&#233;ficit de vitamina D (VD) est&#225; asociado a TSM. Objetivo: Evaluar la deficiencia de VD en adolescentes con TSM hospitalizados en una Unidad Hospitalaria de Adolescencia (UHA), y explorar factores asociados. Pacientes y M&#233;todo: Estudio observacional, anal&#237;tico, de corte transversal. Se incluyeron todos los adolescentes entre 10 a 17 a&#241;os, con TSM, ingresados a la UHA entre el 2019 y 2021, en quienes se realiz&#243; medici&#243;n de 25 hidroxi-vitamina D (25-OH VD). Se evalu&#243; la asociaci&#243;n entre concentraci&#243;n s&#233;rica 25-OH VD y variables de inter&#233;s (sociodemogr&#225;ficas, comorbilidad) en un modelo multivariado, incluyendo estado nutricional (OMS 2007), estaci&#243;n del a&#241;o, trastorno del &#225;nimo, tipo de alimentaci&#243;n, edad y sexo, entre otras. Resultados: Se incluyeron 164 adolescentes. La deficiencia de VD fue 76,6% (44,8% deficiencia severa). El d&#233;ficit de VD fue de 90,9% en adolescentes con sobrepeso y 82,2% con obesidad. El promedio ajustado de 25-OH VD fue de 23,3 ng/ml (IC 95%: 16,7-30,0) en malnutrici&#243;n por d&#233;ficit, versus 14,2 ng/ml (IC 95%: 10,1-18,3) en sobrepeso (p&lt; 0,01); y 21,1 mg/ml (IC 95%: 15,7-26,4) en los meses de diciembre-febrero versus 16,2 ng/ml (IC 95%: 12,1-20,2) en junio-agosto (p= 0,02). No hubo diferencias seg&#250;n trastorno de &#225;nimo. Conclusiones: Los adolescentes con TSM hospitalizados tienen un alto d&#233;ficit de VD. Se encontr&#243; asociaci&#243;n estad&#237;sticamente significativa entre niveles de VD y las variables estado nutricional y estaci&#243;n del a&#241;o. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Andes Pediatrica is the property of Revista Chilena de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.32641/andespediatr.v96i3.5445
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        Text: Spanish
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      – SubjectFull: VITAMIN D deficiency
        Type: general
      – SubjectFull: MENTAL illness
        Type: general
      – SubjectFull: HOSPITAL patients
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      – SubjectFull: TEENAGERS
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      – SubjectFull: NUTRITIONAL status
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      – SubjectFull: OVERWEIGHT persons
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      – SubjectFull: SEASONAL physiological variations
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              Text: Jun2025
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