Los premios Nobel de Medicina: una historia a destacar.

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Title: Los premios Nobel de Medicina: una historia a destacar.
Alternate Title: The Nobel Prizes in Medicine: a story worth highlighting.
Authors: Córdova Pluma, Víctor Huggo
Source: Medicina Interna de México. nov2025, Vol. 41 Issue 11, p645-646. 2p.
Subjects: IMMUNOLOGICAL tolerance, AUTOIMMUNE diseases, MEDICAL research personnel, IMMUNOLOGISTS, DRUGS, NOBEL Prizes, REGULATORY T cells, NOBEL, Alfred Bernhard, 1833-1896
Abstract (English): The article focuses on the awarding of the 2025 Nobel Prize in Medicine to Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their contributions to the understanding of immune tolerance and its relationship with autoimmune diseases. Sakaguchi was recognized for identifying regulatory T cells, while Brunkow and Ramsdell studied the Foxp3 gene in mouse models, revealing mutations that affect humans with various autoimmune conditions. Additionally, the importance of collaboration and diversity in science is discussed, as well as the use of advanced technology and artificial intelligence in their research. The article invites reflection on the impact of these discoveries on the treatment of diseases such as cancer and arthritis. [Extracted from the article]
Abstract (Spanish): El artículo se centra en la entrega del Premio Nobel de Medicina 2025 a Mary Brunkow, Fred Ramsdell y Shimon Sakaguchi por sus contribuciones al entendimiento de la tolerancia inmunitaria y su relación con enfermedades autoinmunitarias. Sakaguchi fue reconocido por identificar las células T reguladoras, mientras que Brunkow y Ramsdell estudiaron el gen Foxp3 en modelos de ratones, revelando mutaciones que afectan a humanos con diversas condiciones autoinmunitarias. Además, se discute la importancia de la colaboración y diversidad en la ciencia, así como el uso de tecnología avanzada e inteligencia artificial en sus investigaciones. El artículo invita a reflexionar sobre el impacto de estos descubrimientos en el tratamiento de enfermedades como el cáncer y la artritis. [Extracted from the article]
Copyright of Medicina Interna de México is the property of Colegio de Medicina Interna de Mexico and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
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  Data: Los premios Nobel de Medicina: una historia a destacar.
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  Data: The Nobel Prizes in Medicine: a story worth highlighting.
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  Data: <searchLink fieldCode="AR" term="%22Córdova+Pluma%2C+Víctor+Huggo%22">Córdova Pluma, Víctor Huggo</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Medicina+Interna+de+México%22">Medicina Interna de México</searchLink>. nov2025, Vol. 41 Issue 11, p645-646. 2p.
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  Data: <searchLink fieldCode="DE" term="%22IMMUNOLOGICAL+tolerance%22">IMMUNOLOGICAL tolerance</searchLink><br /><searchLink fieldCode="DE" term="%22AUTOIMMUNE+diseases%22">AUTOIMMUNE diseases</searchLink><br /><searchLink fieldCode="DE" term="%22MEDICAL+research+personnel%22">MEDICAL research personnel</searchLink><br /><searchLink fieldCode="DE" term="%22IMMUNOLOGISTS%22">IMMUNOLOGISTS</searchLink><br /><searchLink fieldCode="DE" term="%22DRUGS%22">DRUGS</searchLink><br /><searchLink fieldCode="DE" term="%22NOBEL+Prizes%22">NOBEL Prizes</searchLink><br /><searchLink fieldCode="DE" term="%22REGULATORY+T+cells%22">REGULATORY T cells</searchLink><br /><searchLink fieldCode="DE" term="%22NOBEL%2C+Alfred+Bernhard%2C+1833-1896%22">NOBEL, Alfred Bernhard, 1833-1896</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: The article focuses on the awarding of the 2025 Nobel Prize in Medicine to Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their contributions to the understanding of immune tolerance and its relationship with autoimmune diseases. Sakaguchi was recognized for identifying regulatory T cells, while Brunkow and Ramsdell studied the Foxp3 gene in mouse models, revealing mutations that affect humans with various autoimmune conditions. Additionally, the importance of collaboration and diversity in science is discussed, as well as the use of advanced technology and artificial intelligence in their research. The article invites reflection on the impact of these discoveries on the treatment of diseases such as cancer and arthritis. [Extracted from the article]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: El artículo se centra en la entrega del Premio Nobel de Medicina 2025 a Mary Brunkow, Fred Ramsdell y Shimon Sakaguchi por sus contribuciones al entendimiento de la tolerancia inmunitaria y su relación con enfermedades autoinmunitarias. Sakaguchi fue reconocido por identificar las células T reguladoras, mientras que Brunkow y Ramsdell estudiaron el gen Foxp3 en modelos de ratones, revelando mutaciones que afectan a humanos con diversas condiciones autoinmunitarias. Además, se discute la importancia de la colaboración y diversidad en la ciencia, así como el uso de tecnología avanzada e inteligencia artificial en sus investigaciones. El artículo invita a reflexionar sobre el impacto de estos descubrimientos en el tratamiento de enfermedades como el cáncer y la artritis. [Extracted from the article]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Medicina Interna de México is the property of Colegio de Medicina Interna de Mexico and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.24245/mim.v41i11.10809
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      – Code: spa
        Text: Spanish
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      Pagination:
        PageCount: 2
        StartPage: 645
    Subjects:
      – SubjectFull: IMMUNOLOGICAL tolerance
        Type: general
      – SubjectFull: AUTOIMMUNE diseases
        Type: general
      – SubjectFull: MEDICAL research personnel
        Type: general
      – SubjectFull: IMMUNOLOGISTS
        Type: general
      – SubjectFull: DRUGS
        Type: general
      – SubjectFull: NOBEL Prizes
        Type: general
      – SubjectFull: REGULATORY T cells
        Type: general
      – SubjectFull: NOBEL, Alfred Bernhard, 1833-1896
        Type: general
    Titles:
      – TitleFull: Los premios Nobel de Medicina: una historia a destacar.
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          Dates:
            – D: 01
              M: 11
              Text: nov2025
              Type: published
              Y: 2025
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