Trombocitopenias en pacientes hospitalizados: análisis prospectivo de incidencia, diagnósticos clínicos y etiología.

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Bibliographic Details
Title: Trombocitopenias en pacientes hospitalizados: análisis prospectivo de incidencia, diagnósticos clínicos y etiología.
Alternate Title: Prospective analysis of the incidence, clinical diagnoses and aetiology of thrombocytopenia in hospitalised patients.
Authors: Aguilera Monter, Carlos Adrián1, Mondragón Castañeda, Marisa2, Gerónimo Guevara, Nancy3, Rodríguez Weber, Federico L.4 federicorodriguez@saludangeles.mx
Source: Medicina Interna de México. nov2025, Vol. 41 Issue 11, p657-663. 7p.
Subjects: THROMBOCYTOPENIA, HOSPITAL patients, DISEASE incidence, DIAGNOSIS, SOCIODEMOGRAPHIC factors, SCIENTIFIC observation, ETIOLOGY of diseases
Geographic Terms: MEXICO City (Mexico)
Abstract (English): OBJECTIVE: To identify the diseases, clinical circumstances and demographic factors associated with thrombocytopenia in hospitalised patients. MATERIALS AND METHODS: A prospective observational study was conducted on patients admitted to the inpatient and intermediate care unit of a private hospital in southern Mexico City between 19 August 2024 and 12 January 2025. The analysed population consisted of patients with thrombocytopenia of any degree. Medical records, files and laboratory reports were reviewed. RESULTS: A total of 110 patients were studied, of whom 72 (64.9%) were from the hospitalisation area and 39 (35.1%) were from intermediate care. Of these patients, 66 (59.5%) were male and 45 (40.5%) were female. The age range was 16 to 97 years, with an average age of 63.16 years. Three groups were formed: 62 patients aged over 70 (56.3%), 38 patients aged between 35 and 70 (34.5%), and 11 patients aged under 35 (10%). Thrombocytopenia severity was classified as mild in 55% (n = 62), moderate in 25.2% (n = 28) and severe in 19.8% (n = 22) of cases. CONCLUSION: Thrombocytopenia is a common finding in hospitalised patients, with a higher incidence in males and older adults. While most cases are found among patients admitted to general hospital wards, those admitted to intermediate care tend to be more severe, particularly in cases associated with sepsis. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): OBJETIVO: Identificar las enfermedades, circunstancias clínicas y factores demográficos asociados con la trombocitopenia en pacientes hospitalizados. MATERIALES Y MÉTODOS: Estudio prospectivo y observacional efectuado en pacientes ingresados entre el 19 de agosto del 2024 y el 12 de enero del 2025 al área de hospitalización y terapia intermedia de un hospital privado al sur de la Ciudad de México. La población analizada fueron pacientes con plaquetopenia de cualquier grado. Se revisaron las historias clínicas, expedientes y reportes de laboratorio. RESULTADOS: Se estudiaron 110 pacientes: 72 (64.9 %) del área de hospitalización y 39 (35.1%) de terapia intermedia; 66 pacientes (59.5%) eran de sexo masculino y 45 (40.5%) del femenino. Los límites de edad fueron 16 y 97 años, con una edad promedio de 63.16 años. Se integraron tres grupos: 62 pacientes mayores de 70 años (56.3%), 38 pacientes entre 35 y 70 años (34.5%) y 11 menores de 35 años (10%). La gravedad de la trombocitopenia se clasificó en leve en 55% (n = 62), moderada en 25.2% (n = 28) y grave en 19.8% (n = 22). CONCLUSIÓN: La trombocitopenia constituye un hallazgo frecuente en pacientes hospitalizados, con mayor incidencia en el sexo masculino y en adultos mayores. Si bien la mayoría de los casos corresponde a pacientes ingresados a unidades de hospitalización general, los admitidos en terapia intermedia se hospitalizan clínicamente más graves, sobre todo en el contexto de causas asociadas con sepsis. [ABSTRACT FROM AUTHOR]
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Database: MedicLatina
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