View in EDS HTML Full Text PDF Full Text

Manejo del dolor crónico posquirúrgico y oncológico tras cirugía cáncer de mama y posterior recidiva ósea.

Saved in:
Bibliographic Details
Title: Manejo del dolor crónico posquirúrgico y oncológico tras cirugía cáncer de mama y posterior recidiva ósea.
Alternate Title: Management of chronic postsurgical and oncological pain after breast cancer surgery and metachronous bone metastasis.
Authors: Morales-Viveros, Camila1 (AUTHOR) camila.morales.viveros@hmar.cat, Moltó-García, Luis1 (AUTHOR), Bande-Julián, David1 (AUTHOR), Rodríguez-Rivas, Uxia1 (AUTHOR), Comps-Vicente, Olga1 (AUTHOR)
Source: Dolor: Investigación, Clínica & Terapéutica. 2025, Vol. 40 Issue 4, p130-132. 3p.
Subjects: CHRONIC pain, BREAST cancer, PAIN management, NEURALGIA, METASTASIS, DRUG administration, SPINAL infusions, ANALGESICS
Abstract (English): The intrathecal therapy has been used further than 40 years and offers several benefits in selected cases when compared with systemic opioids therapy for chronic cancer pain and non-oncologic pain. These include the direct delivery of the drug to its site of action –the dorsal horn of the spinal cord–, bypassing first-pass metabolism and the blood-brain barrier. These mechanisms allow the use of a lower necessary dosage to obtain the desired analgesic effect and, in turn, less interaction of the administered drug with other systemic receptors, reducing its adverse or undesirable effects. Morphine and Ziconotide are the only agents approved by the FDA (Food and Drug Administration) for intrathecal therapy in chronic pain. We present the case of a patient with neuropathic pain after breast cancer surgery, initially treated with oral and transdermal opioids, adjuvants and spinal cord stimulation (SCS). After several years of clinical stability, she presented a significant increase in the level of pain in the context of metachronous bone and mediastinal metastases. Therefore, we proposed a new analgesic approach including nociceptive and neuropathic pain treatment in a systemic strategy. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): La terapia intratecal, en uso hace más de 40 años, ofrece varios beneficios en casos bien seleccionados, con respecto a la administración sistémica de opioides en pacientes que padecen dolor crónico refractario oncológico y no oncológico. Entre ellos cabe mencionar la entrega directa del fármaco en su sitio de acción –asta dorsal de la médula espinal–, saltando el metabolismo de primer paso y la barrera hematoencefálica. Estos mecanismos permiten el uso de una menor dosificación necesaria para obtener el efecto analgésico deseado y a su vez menor interacción del fármaco administrado con los demás receptores sistémicos, lo que disminuye los efectos adversos o indeseados de este. Morfina y ziconotida son los únicos agentes aprobados por la FDA (Food and Drug Administration) para terapia intratecal en dolor crónico. Presentamos el caso de una paciente con dolor neuropático tras cirugía oncológica de mama, inicialmente tratada con opioides vía oral y transdérmica, coadyuvantes y terapia de electroestimulación (EEM) de cordones posteriores. Con lo anterior, se logra estabilidad clínica durante años hasta la aparición de metástasis óseas y mediastínicas asociadas a un incremento considerable del nivel de dolor. En este contexto, fue necesario plantear una nueva estrategia de abordaje analgésico con enfoque sistémico que incluye el tratamiento del dolor nociceptivo y neuropático. [ABSTRACT FROM AUTHOR]
Copyright of Dolor: Investigación, Clínica & Terapéutica is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: lth
DbLabel: MedicLatina
An: 188931255
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Manejo del dolor crónico posquirúrgico y oncológico tras cirugía cáncer de mama y posterior recidiva ósea.
– Name: TitleAlt
  Label: Alternate Title
  Group: TiAlt
  Data: Management of chronic postsurgical and oncological pain after breast cancer surgery and metachronous bone metastasis.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Morales-Viveros%2C+Camila%22">Morales-Viveros, Camila</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> camila.morales.viveros@hmar.cat</i><br /><searchLink fieldCode="AR" term="%22Moltó-García%2C+Luis%22">Moltó-García, Luis</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bande-Julián%2C+David%22">Bande-Julián, David</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rodríguez-Rivas%2C+Uxia%22">Rodríguez-Rivas, Uxia</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Comps-Vicente%2C+Olga%22">Comps-Vicente, Olga</searchLink><relatesTo>1</relatesTo> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Dolor%3A+Investigación%2C+Clínica+%26+Terapéutica%22">Dolor: Investigación, Clínica & Terapéutica</searchLink>. 2025, Vol. 40 Issue 4, p130-132. 3p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22CHRONIC+pain%22">CHRONIC pain</searchLink><br /><searchLink fieldCode="DE" term="%22BREAST+cancer%22">BREAST cancer</searchLink><br /><searchLink fieldCode="DE" term="%22PAIN+management%22">PAIN management</searchLink><br /><searchLink fieldCode="DE" term="%22NEURALGIA%22">NEURALGIA</searchLink><br /><searchLink fieldCode="DE" term="%22METASTASIS%22">METASTASIS</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+administration%22">DRUG administration</searchLink><br /><searchLink fieldCode="DE" term="%22SPINAL+infusions%22">SPINAL infusions</searchLink><br /><searchLink fieldCode="DE" term="%22ANALGESICS%22">ANALGESICS</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: The intrathecal therapy has been used further than 40 years and offers several benefits in selected cases when compared with systemic opioids therapy for chronic cancer pain and non-oncologic pain. These include the direct delivery of the drug to its site of action –the dorsal horn of the spinal cord–, bypassing first-pass metabolism and the blood-brain barrier. These mechanisms allow the use of a lower necessary dosage to obtain the desired analgesic effect and, in turn, less interaction of the administered drug with other systemic receptors, reducing its adverse or undesirable effects. Morphine and Ziconotide are the only agents approved by the FDA (Food and Drug Administration) for intrathecal therapy in chronic pain. We present the case of a patient with neuropathic pain after breast cancer surgery, initially treated with oral and transdermal opioids, adjuvants and spinal cord stimulation (SCS). After several years of clinical stability, she presented a significant increase in the level of pain in the context of metachronous bone and mediastinal metastases. Therefore, we proposed a new analgesic approach including nociceptive and neuropathic pain treatment in a systemic strategy. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: La terapia intratecal, en uso hace más de 40 años, ofrece varios beneficios en casos bien seleccionados, con respecto a la administración sistémica de opioides en pacientes que padecen dolor crónico refractario oncológico y no oncológico. Entre ellos cabe mencionar la entrega directa del fármaco en su sitio de acción –asta dorsal de la médula espinal–, saltando el metabolismo de primer paso y la barrera hematoencefálica. Estos mecanismos permiten el uso de una menor dosificación necesaria para obtener el efecto analgésico deseado y a su vez menor interacción del fármaco administrado con los demás receptores sistémicos, lo que disminuye los efectos adversos o indeseados de este. Morfina y ziconotida son los únicos agentes aprobados por la FDA (Food and Drug Administration) para terapia intratecal en dolor crónico. Presentamos el caso de una paciente con dolor neuropático tras cirugía oncológica de mama, inicialmente tratada con opioides vía oral y transdérmica, coadyuvantes y terapia de electroestimulación (EEM) de cordones posteriores. Con lo anterior, se logra estabilidad clínica durante años hasta la aparición de metástasis óseas y mediastínicas asociadas a un incremento considerable del nivel de dolor. En este contexto, fue necesario plantear una nueva estrategia de abordaje analgésico con enfoque sistémico que incluye el tratamiento del dolor nociceptivo y neuropático. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Dolor: Investigación, Clínica & Terapéutica is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=188931255
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.24875/DOL.M25000033
    Languages:
      – Code: spa
        Text: Spanish
    PhysicalDescription:
      Pagination:
        PageCount: 3
        StartPage: 130
    Subjects:
      – SubjectFull: CHRONIC pain
        Type: general
      – SubjectFull: BREAST cancer
        Type: general
      – SubjectFull: PAIN management
        Type: general
      – SubjectFull: NEURALGIA
        Type: general
      – SubjectFull: METASTASIS
        Type: general
      – SubjectFull: DRUG administration
        Type: general
      – SubjectFull: SPINAL infusions
        Type: general
      – SubjectFull: ANALGESICS
        Type: general
    Titles:
      – TitleFull: Manejo del dolor crónico posquirúrgico y oncológico tras cirugía cáncer de mama y posterior recidiva ósea.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Morales-Viveros, Camila
      – PersonEntity:
          Name:
            NameFull: Moltó-García, Luis
      – PersonEntity:
          Name:
            NameFull: Bande-Julián, David
      – PersonEntity:
          Name:
            NameFull: Rodríguez-Rivas, Uxia
      – PersonEntity:
          Name:
            NameFull: Comps-Vicente, Olga
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: 2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 02140659
          Numbering:
            – Type: volume
              Value: 40
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Dolor: Investigación, Clínica & Terapéutica
              Type: main
ResultId 1