Bibliographic Details
| Title: |
Bilateral atypical femoral fractures caused by long-term use of bisphosphonate treatment in postmenopausal osteoporosis. |
| Alternate Title: |
Fracturas femorales atípicas bilaterales causadas por uso prolongado de tratamiento con bifosfonato en osteoporosis postmenopáusica. |
| Authors: |
Jasqui-Remba, S.1 drsjasqui@gmail.com, Grobeisen-Levin, S.1,2, Jasqui-Romano, S.1,3, Rodríguez-Rejón, G.1 |
| Source: |
Acta Ortopédica Mexicana. Nov/Dec2025, Vol. 39 Issue 6, p401-404. 4p. |
| Subjects: |
FEMORAL fractures, DIPHOSPHONATES, OSTEOPOROSIS, INTRAMEDULLARY fracture fixation, OSTEOPOROSIS in women, TREATMENT duration, BONE remodeling, PATIENT monitoring |
| Abstract (English): |
This paper presents two cases of bilateral atypical femoral fractures in postmenopausal women who underwent prolonged bisphosphonate therapy for osteoporosis. Both patients, aged 83 and 76, experienced fractures after long-term bisphosphonate treatment, highlighting concerns about suppressed bone turnover. Each case was treated with intramedullary nailing, and bisphosphonates were discontinued in favor of alternative therapies. These cases underscore the risks of atypical femoral fractures linked to extended bisphosphonate use, emphasizing the need for careful patient monitoring and further research to optimize osteoporosis treatment strategies and prevent such complications. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
Este artículo presenta dos casos de fracturas femorales atípicas bilaterales en mujeres posmenopáusicas con tratamiento prolongado con bifosfonatos para la osteoporosis. Ambas pacientes, de 83 y 76 años, sufrieron fracturas tras un tratamiento prolongado con bifosfonatos, lo que pone de manifiesto la preocupación que suscita la supresión del recambio óseo. En ambos casos, la reducción de las fracturas fue mediante colocación de clavos intramedulares y se suspendió el tratamiento con bifosfonatos cambiando el manejo por terapias alternativas. Estos casos dan relevancia a los riesgos de fracturas femorales atípicas relacionadas con el uso prolongado de bifosfonatos, y subrayan la necesidad de un seguimiento cuidadoso de los pacientes y de más investigación para optimizar las estrategias de tratamiento de la osteoporosis y prevenir tales complicaciones. [ABSTRACT FROM AUTHOR] |
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| Database: |
MedicLatina |
