Adherencia a tratamientos antibióticos desde la farmacia comunitaria: análisis por grupos terapéuticos y factores asociados.
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| Title: | Adherencia a tratamientos antibióticos desde la farmacia comunitaria: análisis por grupos terapéuticos y factores asociados. |
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| Alternate Title: | Adherence to Antibiotic Treatments in Community Pharmacy: Analysis by Therapeutic Groups and Associated Factors. |
| Authors: | Zarauz Céspedes, José María1 jose.zarauzcespedes@uchceu.es, Valdeolmillos Carbó, Laura2 |
| Source: | Farmacéuticos Comunitarios. ene2026, Vol. 18 Issue 1, p1-9. 9p. |
| Subjects: | PATIENT compliance, PENICILLIN, SOCIODEMOGRAPHIC factors, PHARMACEUTICAL industry, DRUGSTORES, DRUG resistance in bacteria |
| Geographic Terms: | SPAIN, MURCIA (Spain) |
| Abstract (English): | Introduction: Non-adherence to antibiotic treatments contributes to the development of resistance. Community pharmacies provide an opportunity to assess and improve therapeutic adherence. This study analyzes which antibiotic groups present the highest non-adherence rates. Objective: To identify the therapeutic groups of antibiotics with the highest non-adherence in community pharmacy and to analyze associated factors such as age, sex, and reasons for treatment discontinuation. Methods: An observational, descriptive, and prospective study was conducted over 12 months in two pharmacies in a coastal town in Murcia, Spain. A total of 500 patients receiving antibiotic treatment were included. Sociodemographic variables and treatment characteristics were recorded. After 15 days, adherence was assessed using the Morisky-Green-Levine test, and reasons for non-adherence were documented. Chi-square statistical analysis and relative risks (RR) were calculated. Results: Of the 363 patients who completed the study, 37.2% did not adhere to their treatment. The highest non-adherence rates for oral treatments were observed in penicillin combinations with betalactamase inhibitors (52.4%) and extended-spectrum penicillins (46.8%). The most frequent reason was forgetfulness, followed by schedule changes and perceived clinical improvement. No significant differences were found by sex (p = 0.136) or age group (p = 0.209). The RR was higher for penicillin combinations (RR = 1.40; 95% CI: 1.10-1.78) and lower for macrolides (RR = 0.43; 95% CI: 0.23-0.79). Conclusions: Penicillins, especially combinations with beta-lactamase inhibitors, and topical antibiotics present a higher risk of non-adherence. Interventions from primary care and particularly from community pharmacy should be reinforced to improve adherence, especially in these groups. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Introducción: El incumplimiento de los tratamientos antibióticos favorece la aparición de resistencias. La farmacia comunitaria permite evaluar y mejorar la adherencia terapéutica. Este estudio analiza qué grupos antibióticos presentan mayores tasas de incumplimiento. Objetivo: Identificar los grupos terapéuticos de antibióticos con mayor incumplimiento en farmacia comunitaria y analizar factores asociados como edad, sexo y motivos de abandono. Método: Estudio observacional, descriptivo y prospectivo durante 12 meses en dos farmacias de una localidad situada en la costa de Murcia. Se incluyeron 500 pacientes a los que se dispensó tratamiento antibiótico. Se recogieron variables sociodemográficas y características del tratamiento. A los 15 días, se evaluó la adherencia mediante el test de Morisky-Green-Levine y se registraron los motivos de incumplimiento. Se utilizó el análisis estadístico de chi-cuadrado y se calcularon riesgos relativos (RR). Resultados: De los 363 pacientes que completaron el estudio, el 37,2% incumplió el tratamiento. Las mayores tasas de incumplimiento de tratamientos vía oral se observaron en las combinaciones de penicilinas con inhibidores de betalactamasas (52,4%) y penicilinas de espectro ampliado (46,8%). El motivo más frecuente fue el olvido, seguido del horario y la mejoría clínica. No se hallaron diferencias significativas según sexo (p = 0,136) ni entre grupos de edad (p = 0,209). El RR fue mayor en las combinaciones de penicilinas (RR = 1,40; IC95%: 1,10-1,78) y menor en los macrólidos (RR = 0,43; IC95%: 0,23-0,79). Conclusiones: Las penicilinas, especialmente las combinaciones con inhibidores de beta-lactamasa y los antibióticos para uso tópico presentan mayor riesgo de incumplimiento. Se recomienda reforzar intervenciones desde atención primaria y especialmente desde la farmacia comunitaria, dirigidas a mejorar la adherencia, especialmente en estos grupos. [ABSTRACT FROM AUTHOR] |
| Copyright of Farmacéuticos Comunitarios is the property of Sociedad Espanola de Farmacia Familiar y Comunitaria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
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| Items | – Name: Title Label: Title Group: Ti Data: Adherencia a tratamientos antibióticos desde la farmacia comunitaria: análisis por grupos terapéuticos y factores asociados. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Adherence to Antibiotic Treatments in Community Pharmacy: Analysis by Therapeutic Groups and Associated Factors. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Zarauz+Céspedes%2C+José+María%22">Zarauz Céspedes, José María</searchLink><relatesTo>1</relatesTo><i> jose.zarauzcespedes@uchceu.es</i><br /><searchLink fieldCode="AR" term="%22Valdeolmillos+Carbó%2C+Laura%22">Valdeolmillos Carbó, Laura</searchLink><relatesTo>2</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Farmacéuticos+Comunitarios%22">Farmacéuticos Comunitarios</searchLink>. ene2026, Vol. 18 Issue 1, p1-9. 9p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22PATIENT+compliance%22">PATIENT compliance</searchLink><br /><searchLink fieldCode="DE" term="%22PENICILLIN%22">PENICILLIN</searchLink><br /><searchLink fieldCode="DE" term="%22SOCIODEMOGRAPHIC+factors%22">SOCIODEMOGRAPHIC factors</searchLink><br /><searchLink fieldCode="DE" term="%22PHARMACEUTICAL+industry%22">PHARMACEUTICAL industry</searchLink><br /><searchLink fieldCode="DE" term="%22DRUGSTORES%22">DRUGSTORES</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+resistance+in+bacteria%22">DRUG resistance in bacteria</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22SPAIN%22">SPAIN</searchLink><br /><searchLink fieldCode="DE" term="%22MURCIA+%28Spain%29%22">MURCIA (Spain)</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Introduction: Non-adherence to antibiotic treatments contributes to the development of resistance. Community pharmacies provide an opportunity to assess and improve therapeutic adherence. This study analyzes which antibiotic groups present the highest non-adherence rates. Objective: To identify the therapeutic groups of antibiotics with the highest non-adherence in community pharmacy and to analyze associated factors such as age, sex, and reasons for treatment discontinuation. Methods: An observational, descriptive, and prospective study was conducted over 12 months in two pharmacies in a coastal town in Murcia, Spain. A total of 500 patients receiving antibiotic treatment were included. Sociodemographic variables and treatment characteristics were recorded. After 15 days, adherence was assessed using the Morisky-Green-Levine test, and reasons for non-adherence were documented. Chi-square statistical analysis and relative risks (RR) were calculated. Results: Of the 363 patients who completed the study, 37.2% did not adhere to their treatment. The highest non-adherence rates for oral treatments were observed in penicillin combinations with betalactamase inhibitors (52.4%) and extended-spectrum penicillins (46.8%). The most frequent reason was forgetfulness, followed by schedule changes and perceived clinical improvement. No significant differences were found by sex (p = 0.136) or age group (p = 0.209). The RR was higher for penicillin combinations (RR = 1.40; 95% CI: 1.10-1.78) and lower for macrolides (RR = 0.43; 95% CI: 0.23-0.79). Conclusions: Penicillins, especially combinations with beta-lactamase inhibitors, and topical antibiotics present a higher risk of non-adherence. Interventions from primary care and particularly from community pharmacy should be reinforced to improve adherence, especially in these groups. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Introducción: El incumplimiento de los tratamientos antibióticos favorece la aparición de resistencias. La farmacia comunitaria permite evaluar y mejorar la adherencia terapéutica. Este estudio analiza qué grupos antibióticos presentan mayores tasas de incumplimiento. Objetivo: Identificar los grupos terapéuticos de antibióticos con mayor incumplimiento en farmacia comunitaria y analizar factores asociados como edad, sexo y motivos de abandono. Método: Estudio observacional, descriptivo y prospectivo durante 12 meses en dos farmacias de una localidad situada en la costa de Murcia. Se incluyeron 500 pacientes a los que se dispensó tratamiento antibiótico. Se recogieron variables sociodemográficas y características del tratamiento. A los 15 días, se evaluó la adherencia mediante el test de Morisky-Green-Levine y se registraron los motivos de incumplimiento. Se utilizó el análisis estadístico de chi-cuadrado y se calcularon riesgos relativos (RR). Resultados: De los 363 pacientes que completaron el estudio, el 37,2% incumplió el tratamiento. Las mayores tasas de incumplimiento de tratamientos vía oral se observaron en las combinaciones de penicilinas con inhibidores de betalactamasas (52,4%) y penicilinas de espectro ampliado (46,8%). El motivo más frecuente fue el olvido, seguido del horario y la mejoría clínica. No se hallaron diferencias significativas según sexo (p = 0,136) ni entre grupos de edad (p = 0,209). El RR fue mayor en las combinaciones de penicilinas (RR = 1,40; IC95%: 1,10-1,78) y menor en los macrólidos (RR = 0,43; IC95%: 0,23-0,79). Conclusiones: Las penicilinas, especialmente las combinaciones con inhibidores de beta-lactamasa y los antibióticos para uso tópico presentan mayor riesgo de incumplimiento. Se recomienda reforzar intervenciones desde atención primaria y especialmente desde la farmacia comunitaria, dirigidas a mejorar la adherencia, especialmente en estos grupos. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Farmacéuticos Comunitarios is the property of Sociedad Espanola de Farmacia Familiar y Comunitaria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.33620/FC.2173-9218.(2026).07 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 9 StartPage: 1 Subjects: – SubjectFull: PATIENT compliance Type: general – SubjectFull: PENICILLIN Type: general – SubjectFull: SOCIODEMOGRAPHIC factors Type: general – SubjectFull: PHARMACEUTICAL industry Type: general – SubjectFull: DRUGSTORES Type: general – SubjectFull: DRUG resistance in bacteria Type: general – SubjectFull: SPAIN Type: general – SubjectFull: MURCIA (Spain) Type: general Titles: – TitleFull: Adherencia a tratamientos antibióticos desde la farmacia comunitaria: análisis por grupos terapéuticos y factores asociados. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zarauz Céspedes, José María – PersonEntity: Name: NameFull: Valdeolmillos Carbó, Laura IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: ene2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 18858619 Numbering: – Type: volume Value: 18 – Type: issue Value: 1 Titles: – TitleFull: Farmacéuticos Comunitarios Type: main |
| ResultId | 1 |
