Interacción de linezolid con rifampicina: a propósito de un caso.
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| Title: | Interacción de linezolid con rifampicina: a propósito de un caso. |
|---|---|
| Alternate Title: | Pharmacokinetic interaction between linezolid and rifampicin: A case report. |
| Authors: | Fernández-Vázquez, Ana1 anafernandez.fh@gmail.com, Ayala-Álvarez-Canal, Juan1, García González, David1, Sáez-Villafañe, Mónica1, Dios-Díez, Paula1, José Ortiz-de-Urbina-González, Juan1 |
| Source: | Revista Española de Quimioterapia. feb2026, Vol. 39 Issue 1, p76-79. 4p. |
| Subjects: | LINEZOLID, RIFAMPIN, DRUG monitoring, METHICILLIN-resistant staphylococcus aureus, DRUG dosage, DRUG side effects, DRUG interactions |
| Abstract (English): | The article focuses on the pharmacokinetic interaction between linezolid and rifampicin, highlighting its relevance in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections. It presents the case of a 60-year-old woman with a surgically treated fracture who developed an infection and was treated with linezolid and rifampicin. Although the interaction between the two drugs is known, it emphasizes the lack of established dosing strategies and the importance of therapeutic monitoring to ensure treatment efficacy and minimize the risk of toxicity. Follow-up of the case showed a favorable clinical evolution without significant adverse reactions. [Extracted from the article] |
| Abstract (Spanish): | El artículo se centra en la interacción farmacocinética entre linezolid y rifampicina, destacando su relevancia en el tratamiento de infecciones por Staphylococcus aureus resistente a meticilina (SARM). Se presenta el caso de una mujer de 60 años con una fractura tratada quirúrgicamente, que desarrolló una infección y fue tratada con linezolid y rifampicina. A pesar de que la interacción entre ambos fármacos es conocida, se subraya la falta de estrategias de dosificación establecidas y la importancia de la monitorización terapéutica para asegurar la eficacia del tratamiento y minimizar el riesgo de toxicidad. El seguimiento del caso mostró una evolución clínica favorable sin reacciones adversas significativas. [Extracted from the article] |
| Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 191552954 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Interacción de linezolid con rifampicina: a propósito de un caso. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Pharmacokinetic interaction between linezolid and rifampicin: A case report. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Fernández-Vázquez%2C+Ana%22">Fernández-Vázquez, Ana</searchLink><relatesTo>1</relatesTo><i> anafernandez.fh@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Ayala-Álvarez-Canal%2C+Juan%22">Ayala-Álvarez-Canal, Juan</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22García+González%2C+David%22">García González, David</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Sáez-Villafañe%2C+Mónica%22">Sáez-Villafañe, Mónica</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Dios-Díez%2C+Paula%22">Dios-Díez, Paula</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22José+Ortiz-de-Urbina-González%2C+Juan%22">José Ortiz-de-Urbina-González, Juan</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Revista+Española+de+Quimioterapia%22">Revista Española de Quimioterapia</searchLink>. feb2026, Vol. 39 Issue 1, p76-79. 4p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22LINEZOLID%22">LINEZOLID</searchLink><br /><searchLink fieldCode="DE" term="%22RIFAMPIN%22">RIFAMPIN</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+monitoring%22">DRUG monitoring</searchLink><br /><searchLink fieldCode="DE" term="%22METHICILLIN-resistant+staphylococcus+aureus%22">METHICILLIN-resistant staphylococcus aureus</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+dosage%22">DRUG dosage</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+side+effects%22">DRUG side effects</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+interactions%22">DRUG interactions</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: The article focuses on the pharmacokinetic interaction between linezolid and rifampicin, highlighting its relevance in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections. It presents the case of a 60-year-old woman with a surgically treated fracture who developed an infection and was treated with linezolid and rifampicin. Although the interaction between the two drugs is known, it emphasizes the lack of established dosing strategies and the importance of therapeutic monitoring to ensure treatment efficacy and minimize the risk of toxicity. Follow-up of the case showed a favorable clinical evolution without significant adverse reactions. [Extracted from the article] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: El artículo se centra en la interacción farmacocinética entre linezolid y rifampicina, destacando su relevancia en el tratamiento de infecciones por Staphylococcus aureus resistente a meticilina (SARM). Se presenta el caso de una mujer de 60 años con una fractura tratada quirúrgicamente, que desarrolló una infección y fue tratada con linezolid y rifampicina. A pesar de que la interacción entre ambos fármacos es conocida, se subraya la falta de estrategias de dosificación establecidas y la importancia de la monitorización terapéutica para asegurar la eficacia del tratamiento y minimizar el riesgo de toxicidad. El seguimiento del caso mostró una evolución clínica favorable sin reacciones adversas significativas. [Extracted from the article] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=191552954 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.37201/req/107.2025 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 4 StartPage: 76 Subjects: – SubjectFull: LINEZOLID Type: general – SubjectFull: RIFAMPIN Type: general – SubjectFull: DRUG monitoring Type: general – SubjectFull: METHICILLIN-resistant staphylococcus aureus Type: general – SubjectFull: DRUG dosage Type: general – SubjectFull: DRUG side effects Type: general – SubjectFull: DRUG interactions Type: general Titles: – TitleFull: Interacción de linezolid con rifampicina: a propósito de un caso. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fernández-Vázquez, Ana – PersonEntity: Name: NameFull: Ayala-Álvarez-Canal, Juan – PersonEntity: Name: NameFull: García González, David – PersonEntity: Name: NameFull: Sáez-Villafañe, Mónica – PersonEntity: Name: NameFull: Dios-Díez, Paula – PersonEntity: Name: NameFull: José Ortiz-de-Urbina-González, Juan IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: feb2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 02143429 Numbering: – Type: volume Value: 39 – Type: issue Value: 1 Titles: – TitleFull: Revista Española de Quimioterapia Type: main |
| ResultId | 1 |
