De la absorción a la acción: la fisiología de la vitamina B12.
Saved in:
| Title: | De la absorción a la acción: la fisiología de la vitamina B |
|---|---|
| Authors: | Esparza-Muñiz, Yoselin Andrea1, Valdez-Martínez, Edith1 edith.valdez@imss.gob.mx |
| Source: | Revista de la Facultad de Medicina de la UNAM. ene/feb2026, Vol. 69 Issue 1, p42-51. 10p. |
| Subjects: | VITAMIN B12, ABSORPTION, BLOOD serum analysis, CARRIER proteins, MEDICAL school curriculum, METABOLISM, CELL receptors |
| Abstract (English): | In educating undergraduate and graduate medical students, it is essential to deepen their understanding of physiology, as it provides the basis for understanding the normal mechanisms of human organism function and for inferring the processes that lead to loss of health. Technological advances in the measurement of total serum vitamin B12 concentration, as well as its active form, are grounded in physiological knowledge. Similarly, given the close interrelationship between physiology and pathophysiology, knowledge of vitamin B12 physiology helps to elucidate the internal biological processes that may explain clinical and laboratory findings when analyzing an organism with abnormally low or high serum vitamin B12 concentrations during illness or disease. This article focuses on the physiology of vitamin B12 and explains its structure, absorption process, cellular receptors, binding andcarrier proteins, and key metabolic pathways in a logical and easy-to-understand manner. This knowledge can also serve as a foundation for future scientific research. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | En la formación de las y los estudiantes de medicina de pre y posgrado resulta fundamental fortalecer el conocimiento de la fisiología, por ser la base para comprender los mecanismos normales de funcionamiento del organismo e inferir los procesos de la pérdida de la salud. El desarrollo tecnológico en la medición de la concentración total sérica de la vitamina B12, y de su fracción activa, tiene su sustento en el conocimiento fisiológico. Asimismo, dada la estrecha relación existente entre fisiología y fisiopatología, al analizar, por ejemplo, el funcionamiento de un organismo con niveles séricos anormalmente bajos o elevados de vitamina B12, durante el curso de una enfermedad; el conocimiento de la fisiología de la vitamina B12 facilita imaginar los sucesos/procesos biológicos internos que pudieran explicar los hallazgos clínicos y de laboratorio. Este trabajo se enfoca en la fisiología de la vitamina B12, presenta de manera fácil y lógica su estructura, su proceso de absorción, sus receptores celulares, sus proteínas transportadoras y de unión, y las rutas metabólicas clave en las que participa. Conocimiento que también puede ser usado como un ancla para futuros estudios de investigación científica. [ABSTRACT FROM AUTHOR] |
| Copyright of Revista de la Facultad de Medicina de la UNAM is the property of UNAM, Facultad de Medicina and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: lth DbLabel: MedicLatina An: 191623744 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: De la absorción a la acción: la fisiología de la vitamina B<subscript>12</subscript>. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Esparza-Muñiz%2C+Yoselin+Andrea%22">Esparza-Muñiz, Yoselin Andrea</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Valdez-Martínez%2C+Edith%22">Valdez-Martínez, Edith</searchLink><relatesTo>1</relatesTo><i> edith.valdez@imss.gob.mx</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Revista+de+la+Facultad+de+Medicina+de+la+UNAM%22">Revista de la Facultad de Medicina de la UNAM</searchLink>. ene/feb2026, Vol. 69 Issue 1, p42-51. 10p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22VITAMIN+B12%22">VITAMIN B12</searchLink><br /><searchLink fieldCode="DE" term="%22ABSORPTION%22">ABSORPTION</searchLink><br /><searchLink fieldCode="DE" term="%22BLOOD+serum+analysis%22">BLOOD serum analysis</searchLink><br /><searchLink fieldCode="DE" term="%22CARRIER+proteins%22">CARRIER proteins</searchLink><br /><searchLink fieldCode="DE" term="%22MEDICAL+school+curriculum%22">MEDICAL school curriculum</searchLink><br /><searchLink fieldCode="DE" term="%22METABOLISM%22">METABOLISM</searchLink><br /><searchLink fieldCode="DE" term="%22CELL+receptors%22">CELL receptors</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: In educating undergraduate and graduate medical students, it is essential to deepen their understanding of physiology, as it provides the basis for understanding the normal mechanisms of human organism function and for inferring the processes that lead to loss of health. Technological advances in the measurement of total serum vitamin B12 concentration, as well as its active form, are grounded in physiological knowledge. Similarly, given the close interrelationship between physiology and pathophysiology, knowledge of vitamin B12 physiology helps to elucidate the internal biological processes that may explain clinical and laboratory findings when analyzing an organism with abnormally low or high serum vitamin B12 concentrations during illness or disease. This article focuses on the physiology of vitamin B12 and explains its structure, absorption process, cellular receptors, binding andcarrier proteins, and key metabolic pathways in a logical and easy-to-understand manner. This knowledge can also serve as a foundation for future scientific research. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: En la formación de las y los estudiantes de medicina de pre y posgrado resulta fundamental fortalecer el conocimiento de la fisiología, por ser la base para comprender los mecanismos normales de funcionamiento del organismo e inferir los procesos de la pérdida de la salud. El desarrollo tecnológico en la medición de la concentración total sérica de la vitamina B12, y de su fracción activa, tiene su sustento en el conocimiento fisiológico. Asimismo, dada la estrecha relación existente entre fisiología y fisiopatología, al analizar, por ejemplo, el funcionamiento de un organismo con niveles séricos anormalmente bajos o elevados de vitamina B12, durante el curso de una enfermedad; el conocimiento de la fisiología de la vitamina B12 facilita imaginar los sucesos/procesos biológicos internos que pudieran explicar los hallazgos clínicos y de laboratorio. Este trabajo se enfoca en la fisiología de la vitamina B12, presenta de manera fácil y lógica su estructura, su proceso de absorción, sus receptores celulares, sus proteínas transportadoras y de unión, y las rutas metabólicas clave en las que participa. Conocimiento que también puede ser usado como un ancla para futuros estudios de investigación científica. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Revista de la Facultad de Medicina de la UNAM is the property of UNAM, Facultad de Medicina and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=191623744 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.22201/fm.24484865e.2026.69.1.07 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 10 StartPage: 42 Subjects: – SubjectFull: VITAMIN B12 Type: general – SubjectFull: ABSORPTION Type: general – SubjectFull: BLOOD serum analysis Type: general – SubjectFull: CARRIER proteins Type: general – SubjectFull: MEDICAL school curriculum Type: general – SubjectFull: METABOLISM Type: general – SubjectFull: CELL receptors Type: general Titles: – TitleFull: De la absorción a la acción: la fisiología de la vitamina B12. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Esparza-Muñiz, Yoselin Andrea – PersonEntity: Name: NameFull: Valdez-Martínez, Edith IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: ene/feb2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 00261742 Numbering: – Type: volume Value: 69 – Type: issue Value: 1 Titles: – TitleFull: Revista de la Facultad de Medicina de la UNAM Type: main |
| ResultId | 1 |
