Manifestaciones cutáneas de la artritis reumatoide: reporte de caso y revisión de la literatura.
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| Title: | Manifestaciones cutáneas de la artritis reumatoide: reporte de caso y revisión de la literatura. |
|---|---|
| Alternate Title: | CUTANEOUS MANIFESTATIONS OF RHEUMATOID ARTHRITIS: CASE REPORT AND LITERATURE REVIEW. |
| Authors: | Marín-Murillo, María Camila1 marinmc@javeriana.edu.co, Polanía-Tovar, María Daniela2, Cuellar-Ríos, Isabel Cristina3 |
| Source: | Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica. oct-dic2025, Vol. 33 Issue 4, p1-7. 7p. |
| Subjects: | RHEUMATOID arthritis, CUTANEOUS manifestations of general diseases, SWEET'S syndrome, METHOTREXATE, DISEASE risk factors, RITUXIMAB, AUTOIMMUNE diseases, VASCULITIS |
| Abstract (English): | Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation and damage, often accompanied by extra-articular manifestations. The skin is frequently involved in severe cases of RA. This case reports a 61-year-old woman with long-standing, poorly controlled rheumatoid arthritis who presented with multiple painful skin lesions, including ulcers and plaques, on her hands, elbows, feet, and thighs. Skin biopsies revealed small-vessel vasculitis and neutrophilic infiltration, leading to a diagnosis of leukocytoclastic vasculitis. Treatment with methotrexate and rituximab showed favorable results. Rheumatoid arthritis is associated with both genetic and environmental factors, with smoking being a key environmental risk factor. Dermatological manifestations, including rheumatoid nodules, neutrophilic dermatoses, and vasculitis, can indicate disease severity and guide treatment. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | La artritis reumatoide (AR) es una enfermedad autoinmune crónica caracterizada por inflamación y daño articular, con manifestaciones extraarticulares frecuentes en los casos graves. Este caso describe a una mujer de 61 años con AR de larga data y mal controlada, que presentó múltiples lesiones cutáneas dolorosas, como úlceras y placas en las manos, los codos, los pies y los muslos. Las biopsias revelaron vasculitis de pequeños vasos e infiltración neutrofílica, con diagnóstico de vasculitis leucocitoclástica. El tratamiento con metotrexato y rituximab tuvo buenos resultados. La AR se asocia a factores genéticos y ambientales, de los cuales, el tabaquismo es un factor de riesgo clave. Las manifestaciones dermatológicas, como los nódulos reumatoides, las dermatosis neutrofílicas y las vasculitis, pueden indicar la gravedad de la enfermedad y orientar el tratamiento. [ABSTRACT FROM AUTHOR] |
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| Database: | MedicLatina |
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