Errores de administración de medicamentos de alta alerta en una unidad neonatal.

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Title: Errores de administración de medicamentos de alta alerta en una unidad neonatal.
Alternate Title: High-alert medication administration errors in a neonatal unit.
Authors: Del-Valle Quintana, Luis1,2,3 ldelvalle@uandes.cl, Caterina Milone, María2,4, Regina Secoli, Silvia2,5
Source: Andes Pediatrica. Jan/Feb2026, Vol. 97 Issue 1, p30-39. 10p.
Subjects: MEDICATION errors, INTRAVENOUS therapy, NEONATOLOGY, MEDICATION safety, PATIENT safety, HOSPITAL nursing staff, DRUG infusion pumps, MEDICAL protocols
Abstract (English): Medication errors (MEs) are a frequent and preventable cause of harm, with a high clinical and economic impact, especially when they involve high-alert medications (HAMs). These drugs are generally used in hospitalized neonates, who, due to their physiological immaturity, are at higher risk of suffering from MEs. Objective: To analyze MEs during the intravenous administration of HAMs in a neonatal critical care unit. Patients and Method: Cross-sectional, retrospective study conducted in a neonatal critical care unit of a high-complexity public hospital. Reports of MEs during intravenous administration of HAMs in hospitalized newborns between 2020 and 2024 were included. Records with incomplete information were excluded. Results are presented using absolute and relative frequencies, median, and interquartile range (IQR: p25-p75). Results: A total of 34 MEs were reported, 15/34 (44%) involved HAMs in patients with a median gestational age of 30.0 weeks (IQR: 26.3-36.3); and a median hospital stay of 9 days (IQR: 6.0-21.0). In 5/15 (33%) cases, it was due to wrong infusion rate, lack of care, and misuse of infusion pumps; 10/15 (67%) of MEs did not harm the patient, and 13/15 (87%) were reported by nursing staff. The most frequent HAMs were parenteral nutrition 5/15 (33%) and adrenergic agonists 5/15 (33%). Conclusions: MEs included essential HAMs in intensive care units, whose intravenous infusion was compromised by inappropriate rates attributed to human factors. Thus, it is necessary to strengthen the culture of safety, implement rigorous protocols, and promote ongoing training of the healthcare team, especially in the use of technologies. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Los errores de medicación (EM) son causa frecuente y prevenible de daño, con alto impacto clínico y económico, especialmente cuando involucran medicamentos de alta alerta (MAA). Estos medicamentos son, generalmente, utilizados en neonatos hospitalizados, quienes, por su inmadurez fisiológica, tienen un riesgo mayor de sufrir consecuencias por EM. Objetivo: Analizar EM en la administración intravenosa de MAA en una unidad de paciente crítico neonatal. Pacientes y Método: Estudio transversal, retrospectivo, realizado en una unidad crítica neonatal de un hospital público de alta complejidad. Se incluyeron reportes de EM durante la administración intravenosa de MAA entre 2020-2024. Se excluyeron registros con información incompleta. Los resultados se expresan mediante frecuencias absolutas, relativas, mediana y rango intercuartílico (RIC: p25-p75). Resultados: Fueron notificados 34 EM, 15/34 (44%) involucraron MAA en pacientes con mediana de 30,0 semanas de edad gestacional (RIC: 26,3-36,3); y de 9 días (RIC: 6,0-21,0) de internación. En 5/15 (33%) se debió a velocidad errónea, atribuidos a falta de atenfárción y mal uso de bombas de infusión, 10/15 (67%) de los EM no generaron daño al paciente y 13/15 (87%) fueron reportados por enfermería. Los MAA más frecuentes fueron nutrición parenteral 5/15 (33%) y agonistas adrenérgicos 5/15 (33%). Conclusiones: Los EM involucraron MAA esenciales en unidades de cuidados intensivos, cuya infusión intravenosa fue comprometida por velocidades inapropiadas atribuidas a factores humanos. Se requiere fortalecer la cultura de seguridad, implementar protocolos rigurosos y promover la capacitación continua del equipo de salud, especialmente en el uso de tecnologías. [ABSTRACT FROM AUTHOR]
Copyright of Andes Pediatrica is the property of Revista Chilena de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Group: Ti
  Data: Errores de administración de medicamentos de alta alerta en una unidad neonatal.
– Name: TitleAlt
  Label: Alternate Title
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  Data: High-alert medication administration errors in a neonatal unit.
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  Data: <searchLink fieldCode="AR" term="%22Del-Valle+Quintana%2C+Luis%22">Del-Valle Quintana, Luis</searchLink><relatesTo>1,2,3</relatesTo><i> ldelvalle@uandes.cl</i><br /><searchLink fieldCode="AR" term="%22Caterina+Milone%2C+María%22">Caterina Milone, María</searchLink><relatesTo>2,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Regina+Secoli%2C+Silvia%22">Regina Secoli, Silvia</searchLink><relatesTo>2,5</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Andes+Pediatrica%22">Andes Pediatrica</searchLink>. Jan/Feb2026, Vol. 97 Issue 1, p30-39. 10p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22MEDICATION+errors%22">MEDICATION errors</searchLink><br /><searchLink fieldCode="DE" term="%22INTRAVENOUS+therapy%22">INTRAVENOUS therapy</searchLink><br /><searchLink fieldCode="DE" term="%22NEONATOLOGY%22">NEONATOLOGY</searchLink><br /><searchLink fieldCode="DE" term="%22MEDICATION+safety%22">MEDICATION safety</searchLink><br /><searchLink fieldCode="DE" term="%22PATIENT+safety%22">PATIENT safety</searchLink><br /><searchLink fieldCode="DE" term="%22HOSPITAL+nursing+staff%22">HOSPITAL nursing staff</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+infusion+pumps%22">DRUG infusion pumps</searchLink><br /><searchLink fieldCode="DE" term="%22MEDICAL+protocols%22">MEDICAL protocols</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Medication errors (MEs) are a frequent and preventable cause of harm, with a high clinical and economic impact, especially when they involve high-alert medications (HAMs). These drugs are generally used in hospitalized neonates, who, due to their physiological immaturity, are at higher risk of suffering from MEs. Objective: To analyze MEs during the intravenous administration of HAMs in a neonatal critical care unit. Patients and Method: Cross-sectional, retrospective study conducted in a neonatal critical care unit of a high-complexity public hospital. Reports of MEs during intravenous administration of HAMs in hospitalized newborns between 2020 and 2024 were included. Records with incomplete information were excluded. Results are presented using absolute and relative frequencies, median, and interquartile range (IQR: p25-p75). Results: A total of 34 MEs were reported, 15/34 (44%) involved HAMs in patients with a median gestational age of 30.0 weeks (IQR: 26.3-36.3); and a median hospital stay of 9 days (IQR: 6.0-21.0). In 5/15 (33%) cases, it was due to wrong infusion rate, lack of care, and misuse of infusion pumps; 10/15 (67%) of MEs did not harm the patient, and 13/15 (87%) were reported by nursing staff. The most frequent HAMs were parenteral nutrition 5/15 (33%) and adrenergic agonists 5/15 (33%). Conclusions: MEs included essential HAMs in intensive care units, whose intravenous infusion was compromised by inappropriate rates attributed to human factors. Thus, it is necessary to strengthen the culture of safety, implement rigorous protocols, and promote ongoing training of the healthcare team, especially in the use of technologies. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Los errores de medicación (EM) son causa frecuente y prevenible de daño, con alto impacto clínico y económico, especialmente cuando involucran medicamentos de alta alerta (MAA). Estos medicamentos son, generalmente, utilizados en neonatos hospitalizados, quienes, por su inmadurez fisiológica, tienen un riesgo mayor de sufrir consecuencias por EM. Objetivo: Analizar EM en la administración intravenosa de MAA en una unidad de paciente crítico neonatal. Pacientes y Método: Estudio transversal, retrospectivo, realizado en una unidad crítica neonatal de un hospital público de alta complejidad. Se incluyeron reportes de EM durante la administración intravenosa de MAA entre 2020-2024. Se excluyeron registros con información incompleta. Los resultados se expresan mediante frecuencias absolutas, relativas, mediana y rango intercuartílico (RIC: p25-p75). Resultados: Fueron notificados 34 EM, 15/34 (44%) involucraron MAA en pacientes con mediana de 30,0 semanas de edad gestacional (RIC: 26,3-36,3); y de 9 días (RIC: 6,0-21,0) de internación. En 5/15 (33%) se debió a velocidad errónea, atribuidos a falta de atenfárción y mal uso de bombas de infusión, 10/15 (67%) de los EM no generaron daño al paciente y 13/15 (87%) fueron reportados por enfermería. Los MAA más frecuentes fueron nutrición parenteral 5/15 (33%) y agonistas adrenérgicos 5/15 (33%). Conclusiones: Los EM involucraron MAA esenciales en unidades de cuidados intensivos, cuya infusión intravenosa fue comprometida por velocidades inapropiadas atribuidas a factores humanos. Se requiere fortalecer la cultura de seguridad, implementar protocolos rigurosos y promover la capacitación continua del equipo de salud, especialmente en el uso de tecnologías. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Andes Pediatrica is the property of Revista Chilena de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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        Value: 10.32641/andespediatr.v97i1.5767
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      – Code: spa
        Text: Spanish
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      – SubjectFull: MEDICATION errors
        Type: general
      – SubjectFull: INTRAVENOUS therapy
        Type: general
      – SubjectFull: NEONATOLOGY
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      – SubjectFull: MEDICATION safety
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      – SubjectFull: PATIENT safety
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      – SubjectFull: HOSPITAL nursing staff
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      – SubjectFull: DRUG infusion pumps
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      – SubjectFull: MEDICAL protocols
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    Titles:
      – TitleFull: Errores de administración de medicamentos de alta alerta en una unidad neonatal.
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              Text: Jan/Feb2026
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