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Explorando los desafíos: causas de rechazo de potenciales donantes de órganos en Colombia.

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Title: Explorando los desafíos: causas de rechazo de potenciales donantes de órganos en Colombia.
Alternate Title: Exploring the challenges: main contraindications in organ donation in Colombia.
Authors: Gómez-Montero, Andrea1, García-López, Andrea1 aegarcia@colombianadetrasplantes.com, Cruz-Mususú, William2, Vargas, Luisa2, Escobar, Ximena2, Orellano-Salas, Milena2, Cabas, Santiago1, Girón-Luque, Fernando1,3
Source: Biomédica: Revista del Instituto Nacional de Salud. mar2026, Vol. 46 Issue 1, p83-96. 14p.
Subjects: CONTRAINDICATIONS, ORGAN donation, ORGAN donors, TRANSPLANTATION of organs, tissues, etc., INTERDISCIPLINARY research, BRAIN death
Geographic Terms: COLOMBIA
Abstract (English): Introduction. Organ transplantation is crucial for improving the quality of life of patients with organ failure, but the shortage of donors is a global challenge. In Colombia, the demand exceeds the supply, increasing mortality rates on waiting lists. Objective. To evaluate the causes of contraindications in potential organ donors assessed by Fundonar across three regional centers in the country during 2022. Materials and methods. A descriptive cross-sectional study was conducted based on retrospective data from potential donors reported to the Red de Donación y Trasplantes de Colombia. A total of 1451 cases were evaluated. The causes of contraindications were categorized into medical, medico-legal, and logistical categories. Descriptive statistics were used, the normality of the variables was assessed, and contraindicated donors from each regional center were compared using ANOVA. R software, version 4.0.3, was used. Results. Of the 1451 donors evaluated, 849 had contraindications. Among these, 29.8% presented multiple organ failure, 20.8% had a comorbidity, and 15.3% did not meet the diagnostic criteria for brain death. Conclusion. Most of the medical contraindications could be reconsidered by balancing risks and benefits for the recipients. A personalized and multidisciplinary approach, with evidence-based criteria and real-time decisions tailored to Colombia, could improve organ donation approval rates. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción. El trasplante de órganos es vital para mejorar la calidad de vida de los pacientes con insuficiencia orgánica, pero la escasez de donantes es un desafío global. En Colombia, la demanda supera la oferta, lo cual aumenta la mortalidad de aquellos pacientes en las listas de espera. Objetivo. Analizar las causas de rechazo de potenciales donantes de órganos, según la evaluación de Fundonar en tres regionales del país durante el año 2022. Materiales y métodos. Se llevó a cabo un estudio transversal descriptivo basado en datos retrospectivos de posibles donantes reportados a la Red de Donación y Trasplantes de Colombia. Se incluyeron 1451 casos evaluados. Las causas para rechazar un donante potencial se agruparon en tres categorías: médicas, médico-legales y logísticas. Se utilizó estadística descriptiva, se evaluó la normalidad de las variables y se compararon los donantes con contraindicaciones en cada regional mediante el análisis de varianza. Se utilizó el software R, versión 4.0.3. Resultados. De los 1451 donantes evaluados, 849 tenían causas para el rechazo. De estos, el 29,8 % presentó falla multiorgánica, el 20,8 % tenía alguna comorbilidad y el 15,3 % no cumplía con los criterios diagnósticos de muerte encefálica. Conclusión. La mayoría de las causas médicas de rechazo podrían reconsiderarse sopesando los riesgos y los beneficios para los receptores. Un enfoque personalizado y multidisciplinario, con criterios basados en la evidencia y decisiones en tiempo real adaptadas a Colombia, podría mejorar las tasas de aprobación de donación de órganos. [ABSTRACT FROM AUTHOR]
Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Explorando los desafíos: causas de rechazo de potenciales donantes de órganos en Colombia.
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  Data: Exploring the challenges: main contraindications in organ donation in Colombia.
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  Data: <searchLink fieldCode="AR" term="%22Gómez-Montero%2C+Andrea%22">Gómez-Montero, Andrea</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22García-López%2C+Andrea%22">García-López, Andrea</searchLink><relatesTo>1</relatesTo><i> aegarcia@colombianadetrasplantes.com</i><br /><searchLink fieldCode="AR" term="%22Cruz-Mususú%2C+William%22">Cruz-Mususú, William</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Vargas%2C+Luisa%22">Vargas, Luisa</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Escobar%2C+Ximena%22">Escobar, Ximena</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Orellano-Salas%2C+Milena%22">Orellano-Salas, Milena</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Cabas%2C+Santiago%22">Cabas, Santiago</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Girón-Luque%2C+Fernando%22">Girón-Luque, Fernando</searchLink><relatesTo>1,3</relatesTo>
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  Data: <searchLink fieldCode="DE" term="%22CONTRAINDICATIONS%22">CONTRAINDICATIONS</searchLink><br /><searchLink fieldCode="DE" term="%22ORGAN+donation%22">ORGAN donation</searchLink><br /><searchLink fieldCode="DE" term="%22ORGAN+donors%22">ORGAN donors</searchLink><br /><searchLink fieldCode="DE" term="%22TRANSPLANTATION+of+organs%2C+tissues%2C+etc%2E%22">TRANSPLANTATION of organs, tissues, etc.</searchLink><br /><searchLink fieldCode="DE" term="%22INTERDISCIPLINARY+research%22">INTERDISCIPLINARY research</searchLink><br /><searchLink fieldCode="DE" term="%22BRAIN+death%22">BRAIN death</searchLink>
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  Data: Introduction. Organ transplantation is crucial for improving the quality of life of patients with organ failure, but the shortage of donors is a global challenge. In Colombia, the demand exceeds the supply, increasing mortality rates on waiting lists. Objective. To evaluate the causes of contraindications in potential organ donors assessed by Fundonar across three regional centers in the country during 2022. Materials and methods. A descriptive cross-sectional study was conducted based on retrospective data from potential donors reported to the Red de Donación y Trasplantes de Colombia. A total of 1451 cases were evaluated. The causes of contraindications were categorized into medical, medico-legal, and logistical categories. Descriptive statistics were used, the normality of the variables was assessed, and contraindicated donors from each regional center were compared using ANOVA. R software, version 4.0.3, was used. Results. Of the 1451 donors evaluated, 849 had contraindications. Among these, 29.8% presented multiple organ failure, 20.8% had a comorbidity, and 15.3% did not meet the diagnostic criteria for brain death. Conclusion. Most of the medical contraindications could be reconsidered by balancing risks and benefits for the recipients. A personalized and multidisciplinary approach, with evidence-based criteria and real-time decisions tailored to Colombia, could improve organ donation approval rates. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Introducción. El trasplante de órganos es vital para mejorar la calidad de vida de los pacientes con insuficiencia orgánica, pero la escasez de donantes es un desafío global. En Colombia, la demanda supera la oferta, lo cual aumenta la mortalidad de aquellos pacientes en las listas de espera. Objetivo. Analizar las causas de rechazo de potenciales donantes de órganos, según la evaluación de Fundonar en tres regionales del país durante el año 2022. Materiales y métodos. Se llevó a cabo un estudio transversal descriptivo basado en datos retrospectivos de posibles donantes reportados a la Red de Donación y Trasplantes de Colombia. Se incluyeron 1451 casos evaluados. Las causas para rechazar un donante potencial se agruparon en tres categorías: médicas, médico-legales y logísticas. Se utilizó estadística descriptiva, se evaluó la normalidad de las variables y se compararon los donantes con contraindicaciones en cada regional mediante el análisis de varianza. Se utilizó el software R, versión 4.0.3. Resultados. De los 1451 donantes evaluados, 849 tenían causas para el rechazo. De estos, el 29,8 % presentó falla multiorgánica, el 20,8 % tenía alguna comorbilidad y el 15,3 % no cumplía con los criterios diagnósticos de muerte encefálica. Conclusión. La mayoría de las causas médicas de rechazo podrían reconsiderarse sopesando los riesgos y los beneficios para los receptores. Un enfoque personalizado y multidisciplinario, con criterios basados en la evidencia y decisiones en tiempo real adaptadas a Colombia, podría mejorar las tasas de aprobación de donación de órganos. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.7705/biomedica.7730
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