Cartas al editor.
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| Title: | Cartas al editor. |
|---|---|
| Authors: | Forero-Peña, David A.1,2,3,4, Carrión-Nessi, Fhabián S.1,2, Muñoz-Leal, Sebastián5, Silva-Ramos, Carlos Ramiro6,7, Faccini-Martínez, Álvaro A.8,9 afaccini@homil.gov.co |
| Source: | Biomédica: Revista del Instituto Nacional de Salud. mar2026, Vol. 46 Issue 1, p163-166. 4p. |
| Subjects: | DIAGNOSIS, MICROSCOPY, ANAPLASMOSIS, BABESIOSIS, MOLECULAR diagnosis, EHRLICHIOSIS, PUBLIC health, EPIDEMIOLOGY |
| Geographic Terms: | VENEZUELA |
| Abstract (English): | The letter to the editor focuses on a methodological critique of the study on infections by Ehrlichia spp., Anaplasma spp., and Babesia spp. in humans in Puerto Ordaz, Venezuela. The authors point out that diagnosis based solely on microscopy of Giemsa-stained blood smears has low sensitivity and specificity, which could lead to false positives and overestimate the prevalence of these infections, especially in asymptomatic individuals. Furthermore, they highlight the absence in Venezuela of recognized vectors for these pathogens and the need for molecular methods and multivariate statistical analyses to validate the results. Finally, they recommend that future research use confirmatory techniques and more robust designs to obtain reliable epidemiological data that can guide public health policies. [Extracted from the article] |
| Abstract (Spanish): | La carta al editor se centra en una crítica metodológica al estudio sobre infecciones por Ehrlichia spp., Anaplasma spp. y Babesia spp. en humanos en Puerto Ordaz, Venezuela. Los autores señalan que el diagnóstico basado únicamente en la microscopía de frotis sanguíneos teñidos con Giemsa presenta baja sensibilidad y especificidad, lo que podría generar falsos positivos y sobreestimar la prevalencia de estas infecciones, especialmente en individuos asintomáticos. Además, destacan la ausencia en Venezuela de vectores reconocidos para estos patógenos y la necesidad de métodos moleculares y análisis estadísticos multivariados para validar los resultados. Finalmente, recomiendan que futuras investigaciones utilicen técnicas confirmatorias y diseños más robustos para obtener datos epidemiológicos confiables que orienten políticas de salud pública. [Extracted from the article] |
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| Database: | MedicLatina |
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