Glomerulonefritis por C3 en Colombia Respuesta a prednisona y micofenolato mofetilo en un caso clínico.

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Title: Glomerulonefritis por C3 en Colombia Respuesta a prednisona y micofenolato mofetilo en un caso clínico.
Alternate Title: C3 glomerulonephritis in Colombia The response to prednisone and mycophenolate mofetil in a clinical case.
Authors: Andrés Berrocal-Martínez, Carlos1 carlos.berrocal@correounivalle.edu.co, Hernando Dominguez-Vinayo, Edgar2, Marina Mejía-Paz, Luz3,4, Maria Arrunategui-Ramirez, Ana5, María Zumaqué-Carrascal, Antonio6,7
Source: Acta Medica Colombiana. ene-mar2026, Vol. 51 Issue 1, p1-6. 6p.
Subjects: GLOMERULONEPHRITIS, PREDNISONE, HEMATURIA, MYCOPHENOLIC acid, PROTEINURIA, ACUTE kidney failure, COMPLEMENT activation, NEPHROTIC syndrome
Abstract (English): Introduction: C3 glomerulonephritis is a recent condition that consists of dysregulation of the alternative complement pathway, with subsequent hyperactivation and glomerular C3 deposits. Patients may present hematuria and proteinuria, nephrotic syndrome and, less often, acute kidney injury or rapidly progressive glomerulonephritis. Treatment is still unclear and is based mainly on international reports and series. Case presentation: we present the case of a young adult with nephrotic syndrome secondary to C3 glomerulonephritis who was treated with prednisone and mycophenolate mofetil with a partial clinical and biochemical response. Conclusion: C3 glomerulonephritis is a rare condition with no clearly established treatment options thus far, as shown in the presented case. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción: la glomerulonefritis por C3 es una entidad reciente que consiste en la desregulación de la vía alternativa del complemento, con la consiguiente hiperactivación y la presencia de depósitos glomerulares de C3. Los pacientes pueden presentarse con hematuria y proteinuria, síndrome nefrótico y, menos comúnmente, con injuria renal aguda o glomerulonefritis rápidamente progresiva. El tratamiento continúa siendo incierto y se basa principalmente en reportes y series internacionales. Presentación de caso: se presenta el caso de un adulto joven con síndrome nefrótico secundario a glomerulonefritis por C3, tratado con prednisona y micofenolato mofetilo con respuesta clínica y bioquímica parcial. Conclusión: la glomerulonefritis por C3 representa una entidad infrecuente, con opciones terapéuticas aún no claramente establecidas, como se evidencia en el caso presentado. [ABSTRACT FROM AUTHOR]
Copyright of Acta Medica Colombiana is the property of Acta Medica Colombiana and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
  Group: Ti
  Data: Glomerulonefritis por C3 en Colombia Respuesta a prednisona y micofenolato mofetilo en un caso clínico.
– Name: TitleAlt
  Label: Alternate Title
  Group: TiAlt
  Data: C3 glomerulonephritis in Colombia The response to prednisone and mycophenolate mofetil in a clinical case.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Andrés+Berrocal-Martínez%2C+Carlos%22">Andrés Berrocal-Martínez, Carlos</searchLink><relatesTo>1</relatesTo><i> carlos.berrocal@correounivalle.edu.co</i><br /><searchLink fieldCode="AR" term="%22Hernando+Dominguez-Vinayo%2C+Edgar%22">Hernando Dominguez-Vinayo, Edgar</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Marina+Mejía-Paz%2C+Luz%22">Marina Mejía-Paz, Luz</searchLink><relatesTo>3,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Maria+Arrunategui-Ramirez%2C+Ana%22">Maria Arrunategui-Ramirez, Ana</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22María+Zumaqué-Carrascal%2C+Antonio%22">María Zumaqué-Carrascal, Antonio</searchLink><relatesTo>6,7</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Acta+Medica+Colombiana%22">Acta Medica Colombiana</searchLink>. ene-mar2026, Vol. 51 Issue 1, p1-6. 6p.
– Name: Subject
  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22GLOMERULONEPHRITIS%22">GLOMERULONEPHRITIS</searchLink><br /><searchLink fieldCode="DE" term="%22PREDNISONE%22">PREDNISONE</searchLink><br /><searchLink fieldCode="DE" term="%22HEMATURIA%22">HEMATURIA</searchLink><br /><searchLink fieldCode="DE" term="%22MYCOPHENOLIC+acid%22">MYCOPHENOLIC acid</searchLink><br /><searchLink fieldCode="DE" term="%22PROTEINURIA%22">PROTEINURIA</searchLink><br /><searchLink fieldCode="DE" term="%22ACUTE+kidney+failure%22">ACUTE kidney failure</searchLink><br /><searchLink fieldCode="DE" term="%22COMPLEMENT+activation%22">COMPLEMENT activation</searchLink><br /><searchLink fieldCode="DE" term="%22NEPHROTIC+syndrome%22">NEPHROTIC syndrome</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Introduction: C3 glomerulonephritis is a recent condition that consists of dysregulation of the alternative complement pathway, with subsequent hyperactivation and glomerular C3 deposits. Patients may present hematuria and proteinuria, nephrotic syndrome and, less often, acute kidney injury or rapidly progressive glomerulonephritis. Treatment is still unclear and is based mainly on international reports and series. Case presentation: we present the case of a young adult with nephrotic syndrome secondary to C3 glomerulonephritis who was treated with prednisone and mycophenolate mofetil with a partial clinical and biochemical response. Conclusion: C3 glomerulonephritis is a rare condition with no clearly established treatment options thus far, as shown in the presented case. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Introducción: la glomerulonefritis por C3 es una entidad reciente que consiste en la desregulación de la vía alternativa del complemento, con la consiguiente hiperactivación y la presencia de depósitos glomerulares de C3. Los pacientes pueden presentarse con hematuria y proteinuria, síndrome nefrótico y, menos comúnmente, con injuria renal aguda o glomerulonefritis rápidamente progresiva. El tratamiento continúa siendo incierto y se basa principalmente en reportes y series internacionales. Presentación de caso: se presenta el caso de un adulto joven con síndrome nefrótico secundario a glomerulonefritis por C3, tratado con prednisona y micofenolato mofetilo con respuesta clínica y bioquímica parcial. Conclusión: la glomerulonefritis por C3 representa una entidad infrecuente, con opciones terapéuticas aún no claramente establecidas, como se evidencia en el caso presentado. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Medica Colombiana is the property of Acta Medica Colombiana and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.36104/amc.2026.4830
    Languages:
      – Code: spa
        Text: Spanish
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        PageCount: 6
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    Subjects:
      – SubjectFull: GLOMERULONEPHRITIS
        Type: general
      – SubjectFull: PREDNISONE
        Type: general
      – SubjectFull: HEMATURIA
        Type: general
      – SubjectFull: MYCOPHENOLIC acid
        Type: general
      – SubjectFull: PROTEINURIA
        Type: general
      – SubjectFull: ACUTE kidney failure
        Type: general
      – SubjectFull: COMPLEMENT activation
        Type: general
      – SubjectFull: NEPHROTIC syndrome
        Type: general
    Titles:
      – TitleFull: Glomerulonefritis por C3 en Colombia Respuesta a prednisona y micofenolato mofetilo en un caso clínico.
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            NameFull: Andrés Berrocal-Martínez, Carlos
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            NameFull: Hernando Dominguez-Vinayo, Edgar
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            NameFull: Marina Mejía-Paz, Luz
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            NameFull: Maria Arrunategui-Ramirez, Ana
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            NameFull: María Zumaqué-Carrascal, Antonio
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              Text: ene-mar2026
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              Y: 2026
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