Zone-specific analysis of radiographic pelvic enthesitis in axial spondyloarthritis: identification and associations with mobility, function, and disease activity.
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| Title: | Zone-specific analysis of radiographic pelvic enthesitis in axial spondyloarthritis: identification and associations with mobility, function, and disease activity. |
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| Authors: | Erol, K.1 erolk.md@gmail.com, Tezcan, E. A.2, Sevindik, S.3 |
| Source: | ARP Rheumatology. Jan-Mar2026, Vol. 5 Issue 1, p27-36. 10p. |
| Subjects: | PHYSICAL mobility, FUNCTIONAL status, DISEASE progression, RADIOGRAPHIC processing, SPONDYLOARTHROPATHIES |
| Abstract: | Objectives: To evaluate the frequency of radiographic pelvic enthesitis in patients with axial spondyloarthritis (axSpA), focusing on zone-specific entheseal sites and their associations with disease activity, mobility, and functional outcomes. Methods: This prospective cross-sectional study included 100 patients with radiographic axial spondyloarthritis (r-axSpA) and 100 patients with non-radiographic axial spondyloarthritis (nr-axSpA), who were consecutively admitted to a tertiary hospital’s rheumatology outpatient clinic. Pelvic enthesitis was evaluated in three zones using anteroposterior pelvic X-rays, guided by the recently introduced Radiographic Enthesis Index (REI). Disease activity, spinal mobility, and functionality were assessed using ASDAS-CRP, BASDAI, BASMI, and BASFI. Results: Radiographic enthesitis in the pelvic region was found in 128 patients (64% of the total), comprising 72 (72%) in the r-axSpA group and 56 (56%) in the nr-axSpA group (p = 0.018). Zone 3 (ischiopubic ramus) enthesitis was the most common (59.5%) and was significantly correlated with impaired spinal mobility (BASMI), reduced lumbar lateral flexion, cervical rotation, and modified Schober test scores (p < 0.001). Zone 2 (pubic symphysis) enthesitis was associated with higher disease activity (BASDAI, p = 0.026). Patients with pelvic enthesitis also experienced longer symptom duration (p < 0.001). Conclusions: Pelvic enthesitis detected by AP pelvic radiography is frequent and clinically significant in axSpA. Our findings highlight novel associations with increased disease activity (particularly at the Zone 2) and reduced spinal mobility (notably at the Zone 3). [ABSTRACT FROM AUTHOR] |
| Copyright of ARP Rheumatology is the property of Sociedade Portuguesa de Reumatologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
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| Items | – Name: Title Label: Title Group: Ti Data: Zone-specific analysis of radiographic pelvic enthesitis in axial spondyloarthritis: identification and associations with mobility, function, and disease activity. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Erol%2C+K%2E%22">Erol, K.</searchLink><relatesTo>1</relatesTo><i> erolk.md@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Tezcan%2C+E%2E+A%2E%22">Tezcan, E. A.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Sevindik%2C+S%2E%22">Sevindik, S.</searchLink><relatesTo>3</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22ARP+Rheumatology%22">ARP Rheumatology</searchLink>. Jan-Mar2026, Vol. 5 Issue 1, p27-36. 10p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22PHYSICAL+mobility%22">PHYSICAL mobility</searchLink><br /><searchLink fieldCode="DE" term="%22FUNCTIONAL+status%22">FUNCTIONAL status</searchLink><br /><searchLink fieldCode="DE" term="%22DISEASE+progression%22">DISEASE progression</searchLink><br /><searchLink fieldCode="DE" term="%22RADIOGRAPHIC+processing%22">RADIOGRAPHIC processing</searchLink><br /><searchLink fieldCode="DE" term="%22SPONDYLOARTHROPATHIES%22">SPONDYLOARTHROPATHIES</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Objectives: To evaluate the frequency of radiographic pelvic enthesitis in patients with axial spondyloarthritis (axSpA), focusing on zone-specific entheseal sites and their associations with disease activity, mobility, and functional outcomes. Methods: This prospective cross-sectional study included 100 patients with radiographic axial spondyloarthritis (r-axSpA) and 100 patients with non-radiographic axial spondyloarthritis (nr-axSpA), who were consecutively admitted to a tertiary hospital’s rheumatology outpatient clinic. Pelvic enthesitis was evaluated in three zones using anteroposterior pelvic X-rays, guided by the recently introduced Radiographic Enthesis Index (REI). Disease activity, spinal mobility, and functionality were assessed using ASDAS-CRP, BASDAI, BASMI, and BASFI. Results: Radiographic enthesitis in the pelvic region was found in 128 patients (64% of the total), comprising 72 (72%) in the r-axSpA group and 56 (56%) in the nr-axSpA group (p = 0.018). Zone 3 (ischiopubic ramus) enthesitis was the most common (59.5%) and was significantly correlated with impaired spinal mobility (BASMI), reduced lumbar lateral flexion, cervical rotation, and modified Schober test scores (p < 0.001). Zone 2 (pubic symphysis) enthesitis was associated with higher disease activity (BASDAI, p = 0.026). Patients with pelvic enthesitis also experienced longer symptom duration (p < 0.001). Conclusions: Pelvic enthesitis detected by AP pelvic radiography is frequent and clinically significant in axSpA. Our findings highlight novel associations with increased disease activity (particularly at the Zone 2) and reduced spinal mobility (notably at the Zone 3). [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of ARP Rheumatology is the property of Sociedade Portuguesa de Reumatologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.63032/BLTU9372 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 27 Subjects: – SubjectFull: PHYSICAL mobility Type: general – SubjectFull: FUNCTIONAL status Type: general – SubjectFull: DISEASE progression Type: general – SubjectFull: RADIOGRAPHIC processing Type: general – SubjectFull: SPONDYLOARTHROPATHIES Type: general Titles: – TitleFull: Zone-specific analysis of radiographic pelvic enthesitis in axial spondyloarthritis: identification and associations with mobility, function, and disease activity. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Erol, K. – PersonEntity: Name: NameFull: Tezcan, E. A. – PersonEntity: Name: NameFull: Sevindik, S. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan-Mar2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 27954552 Numbering: – Type: volume Value: 5 – Type: issue Value: 1 Titles: – TitleFull: ARP Rheumatology Type: main |
| ResultId | 1 |
