Comportamiento de la pubertad precoz central antes y durante la pandemia de SARS-CoV-2.

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Title: Comportamiento de la pubertad precoz central antes y durante la pandemia de SARS-CoV-2.
Alternate Title: Trend of Central Precocious Puberty before and during SARS-CoV-2 pandemic.
Authors: Arancibia Cabalá, Mónica1, Pino Astorga, Sebastián2, Rivera Rivera, Alonso2, León Álvarez, Alba Luz3, Dubó Araya, Sebastián4, Campos Cerda, Laura1, Soto Barros, Julio1,5 soto.jb@gmail.com
Source: Andes Pediatrica. mar/abr2026, Vol. 97 Issue 2, p231-238. 8p.
Subjects: PRECOCIOUS puberty, COVID-19 pandemic, LUTEINIZING hormone, ENDOCRINE diseases, PUBERTY, SKELETAL maturity, BODY mass index
Abstract (English): During the SARS-CoV-2 pandemic, there was an increase in the diagnosis of endocrine disorders, notably the onset of central precocious puberty (CPP). Objective: To describe and compare the frequency of precocious puberty onset in two periods, before and during the SARS-CoV-2 pandemic. Patients and Method: Medical records with a confirmed diagnosis of CPP were reviewed from patients treated at Hospital Las Higueras, in Talcahuano, during two periods: 2019-2020 (Group 1, before the pandemic) and 2021-2022 (Group 2, during the pandemic). The variables studied were age at diagnosis, sex, age at onset of puberty, Body Mass Index (BMI) Z-score, Tanner stage, bone age, Luteinizing Hormone (LH), uterine size, and ovarian volumes at diagnosis. Results: There were 98 cases of precocious puberty in Group 1 (96.9% females) and 162 cases in Group 2 (95% females), showing a significant increase in CPP cases during the pandemic period (p < 0.001). Females presented with a higher BMI Z score and more advanced Tanner stage and bone age at diagnosis during the pandemic (p = 0.049, 0.07, and 0.06, respectively). Males were younger at diagnosis of precocious puberty in Group 2 (p = 0.019). Conclusions: Our data show a higher frequency of CPP onset in females and an earlier age at presentation in males during the pandemic period. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Durante la pandemia por SARS CoV-2 se observó un aumento en el diagnóstico de enfermedades endocrinológicas, destacando el debut de pubertad precoz central (PPC). Objetivo: Describir y comparar la frecuencia de debut de pubertad precoz en dos períodos, previo y durante la pandemia por SARS CoV-2. Pacientes y Método: Se revisaron las fichas clínicas con diagnóstico confirmado de PPC de pacientes atendidos en el Hospital Las Higueras, Talcahuano, en 2 períodos: 2019-2020 (Grupo 1, previo a la pandemia) y 2021-2022 (Grupo 2, durante la pandemia). Las variables estudiadas fueron: edad al diagnóstico, sexo, edad de inicio del desarrollo puberal, Z score de índice de masa corporal (IMC), estadio de Tanner, edad ósea, hormona luteinizante (LH), tamaño uterino y volúmenes ováricos al diagnóstico. Resultados: Se presentaron 98 casos de pubertad precoz en el Grupo 1 (96,9% niñas) y 162 casos en el Grupo 2 (95,0% niñas), evidenciándose en las niñas un aumento significativo de los casos de PPC durante el periodo de pandemia (p < 0,001). Las niñas presentaron un mayor z score de IMC, un estadio de tanner y una edad ósea más avanzados al diagnóstico durante la pandemia (p = 0,049, 0,007 y 0,06, respectivamente). En varones, la edad al diagnóstico de pubertad precoz fue menor durante la pandemia (p = 0,019). Conclusiones: Nuestros datos muestran una mayor frecuencia de debut de PPC en las niñas y una menor edad de presentación de ésta en los niños durante el periodo de pandemia. [ABSTRACT FROM AUTHOR]
Copyright of Andes Pediatrica is the property of Revista Chilena de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Comportamiento de la pubertad precoz central antes y durante la pandemia de SARS-CoV-2.
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  Data: Trend of Central Precocious Puberty before and during SARS-CoV-2 pandemic.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Arancibia+Cabal&#225;%2C+M&#243;nica%22&quot;&gt;Arancibia Cabal&#225;, M&#243;nica&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Pino+Astorga%2C+Sebasti&#225;n%22&quot;&gt;Pino Astorga, Sebasti&#225;n&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Rivera+Rivera%2C+Alonso%22&quot;&gt;Rivera Rivera, Alonso&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Le&#243;n+&#193;lvarez%2C+Alba+Luz%22&quot;&gt;Le&#243;n &#193;lvarez, Alba Luz&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Dub&#243;+Araya%2C+Sebasti&#225;n%22&quot;&gt;Dub&#243; Araya, Sebasti&#225;n&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Campos+Cerda%2C+Laura%22&quot;&gt;Campos Cerda, Laura&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Soto+Barros%2C+Julio%22&quot;&gt;Soto Barros, Julio&lt;/searchLink&gt;&lt;relatesTo&gt;1,5&lt;/relatesTo&gt;&lt;i&gt; soto.jb@gmail.com&lt;/i&gt;
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Andes+Pediatrica%22&quot;&gt;Andes Pediatrica&lt;/searchLink&gt;. mar/abr2026, Vol. 97 Issue 2, p231-238. 8p.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22PRECOCIOUS+puberty%22&quot;&gt;PRECOCIOUS puberty&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22COVID-19+pandemic%22&quot;&gt;COVID-19 pandemic&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22LUTEINIZING+hormone%22&quot;&gt;LUTEINIZING hormone&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22ENDOCRINE+diseases%22&quot;&gt;ENDOCRINE diseases&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22PUBERTY%22&quot;&gt;PUBERTY&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22SKELETAL+maturity%22&quot;&gt;SKELETAL maturity&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22BODY+mass+index%22&quot;&gt;BODY mass index&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: During the SARS-CoV-2 pandemic, there was an increase in the diagnosis of endocrine disorders, notably the onset of central precocious puberty (CPP). Objective: To describe and compare the frequency of precocious puberty onset in two periods, before and during the SARS-CoV-2 pandemic. Patients and Method: Medical records with a confirmed diagnosis of CPP were reviewed from patients treated at Hospital Las Higueras, in Talcahuano, during two periods: 2019-2020 (Group 1, before the pandemic) and 2021-2022 (Group 2, during the pandemic). The variables studied were age at diagnosis, sex, age at onset of puberty, Body Mass Index (BMI) Z-score, Tanner stage, bone age, Luteinizing Hormone (LH), uterine size, and ovarian volumes at diagnosis. Results: There were 98 cases of precocious puberty in Group 1 (96.9% females) and 162 cases in Group 2 (95% females), showing a significant increase in CPP cases during the pandemic period (p &lt; 0.001). Females presented with a higher BMI Z score and more advanced Tanner stage and bone age at diagnosis during the pandemic (p = 0.049, 0.07, and 0.06, respectively). Males were younger at diagnosis of precocious puberty in Group 2 (p = 0.019). Conclusions: Our data show a higher frequency of CPP onset in females and an earlier age at presentation in males during the pandemic period. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Durante la pandemia por SARS CoV-2 se observ&#243; un aumento en el diagn&#243;stico de enfermedades endocrinol&#243;gicas, destacando el debut de pubertad precoz central (PPC). Objetivo: Describir y comparar la frecuencia de debut de pubertad precoz en dos per&#237;odos, previo y durante la pandemia por SARS CoV-2. Pacientes y M&#233;todo: Se revisaron las fichas cl&#237;nicas con diagn&#243;stico confirmado de PPC de pacientes atendidos en el Hospital Las Higueras, Talcahuano, en 2 per&#237;odos: 2019-2020 (Grupo 1, previo a la pandemia) y 2021-2022 (Grupo 2, durante la pandemia). Las variables estudiadas fueron: edad al diagn&#243;stico, sexo, edad de inicio del desarrollo puberal, Z score de &#237;ndice de masa corporal (IMC), estadio de Tanner, edad &#243;sea, hormona luteinizante (LH), tama&#241;o uterino y vol&#250;menes ov&#225;ricos al diagn&#243;stico. Resultados: Se presentaron 98 casos de pubertad precoz en el Grupo 1 (96,9% ni&#241;as) y 162 casos en el Grupo 2 (95,0% ni&#241;as), evidenci&#225;ndose en las ni&#241;as un aumento significativo de los casos de PPC durante el periodo de pandemia (p &lt; 0,001). Las ni&#241;as presentaron un mayor z score de IMC, un estadio de tanner y una edad &#243;sea m&#225;s avanzados al diagn&#243;stico durante la pandemia (p = 0,049, 0,007 y 0,06, respectivamente). En varones, la edad al diagn&#243;stico de pubertad precoz fue menor durante la pandemia (p = 0,019). Conclusiones: Nuestros datos muestran una mayor frecuencia de debut de PPC en las ni&#241;as y una menor edad de presentaci&#243;n de &#233;sta en los ni&#241;os durante el periodo de pandemia. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: &lt;i&gt;Copyright of Andes Pediatrica is the property of Revista Chilena de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.32641/andespediatr.v97i2.5669
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        Text: Spanish
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      – SubjectFull: COVID-19 pandemic
        Type: general
      – SubjectFull: LUTEINIZING hormone
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      – SubjectFull: ENDOCRINE diseases
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      – SubjectFull: PUBERTY
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      – SubjectFull: SKELETAL maturity
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      – SubjectFull: BODY mass index
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              Text: mar/abr2026
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