Utilidad de la escala STARZ para predecir lesión renal aguda en recién nacidos atendidos en una Unidad de Cuidados Intensivos Neonatales.

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Title: Utilidad de la escala STARZ para predecir lesión renal aguda en recién nacidos atendidos en una Unidad de Cuidados Intensivos Neonatales.
Alternate Title: Utility of the STARZ scale for predicting acute kidney injury in newborns admitted in a Neonatal Intensive Care Unit.
Authors: García-Martínez, Daniela1,2 dra.danielagarciam@gmail.com, Escobedo-Berumen, Lucía1,2, Carlos Romo-Vázquez, José1, Gerardo-del Hoyo, Moisés Noé1, Lezama-Armenta, Andrés2
Source: Revista Mexicana de Pediatria. ene/feb2026, Vol. 93 Issue 1, p13-19. 7p.
Subjects: ACUTE kidney failure, NEONATAL intensive care units, NEWBORN infants, CLINICAL decision making, SENSITIVITY & specificity (Statistics), CLINICAL prediction rules
Abstract (English): Introduction: acute kidney injury (AKI) in newborns is a frequent complication in the neonatal intensive care unit (NICU). Early identification is key to optimizing clinical management. Objective: to evaluate the usefulness of the STARZ score for predicting AKI in neonates hospitalized in a NICU. Material and methods: a retrospective study was conducted. The STARZ score was applied to all patients, and its diagnostic performance was compared against confirmed cases of AKI according to the KDIGO criteria adapted for neonates, considered the gold standard. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and area under the ROC curve were calculated. Results: 456 neonates were included, of whom 32 (7%) developed AKI. The STARZ score showed a sensitivity of 96.9%, specificity of 78.3%, PPV of 25.2%, and NPV of 99.7%. The area under the curve was 0.977. Conclusions: the STARZ score demonstrated high diagnostic performance for predicting AKI in neonates. Its application in the NICU could facilitate early detection of AKI, optimize renal monitoring, and improve clinical decision-making. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción: la lesión renal aguda (LRA) en recién nacidos es una complicación frecuente en la unidad de cuidados intensivos neonatales (UCIN). Su identificación temprana es clave para optimizar el manejo clínico. Objetivo: evaluar la utilidad de la escala STARZ para predecir LRA en neonatos hospitalizados en una UCIN. Material y métodos: se realizó un estudio retrospectivo. Se aplicó la escala STARZ a todos los pacientes y se comparó su rendimiento diagnóstico frente a los casos confirmados de LRA según los criterios de KDIGO adaptados para neonatos, considerados como el estándar de oro. Se calculó sensibilidad, especificidad, valor predictivo positivo (VPP), valor predictivo negativo (VPN)y área bajo la curva ROC. Resultados: se incluyeron 456 neonatos, de los cuales 32 (7%) desarrollaron LRA. La escala STARZ presentó una sensibilidad de 96.9%, especificidad de 78.3%, VPP de 25.2% y VPN de 99.7%. El área bajo la curva fue de 0.977. Conclusiones: la escala STARZ demostró alto rendimiento diagnóstico para predecir LRA en neonatos. Su aplicación en UCIN podría facilitar una detección temprana de LRA, optimizar el monitoreo renal y mejorar la toma de decisiones clínicas. [ABSTRACT FROM AUTHOR]
Copyright of Revista Mexicana de Pediatria is the property of Sociedad Mexicana de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Utilidad de la escala STARZ para predecir lesión renal aguda en recién nacidos atendidos en una Unidad de Cuidados Intensivos Neonatales.
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  Data: Utility of the STARZ scale for predicting acute kidney injury in newborns admitted in a Neonatal Intensive Care Unit.
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  Data: <searchLink fieldCode="AR" term="%22García-Martínez%2C+Daniela%22">García-Martínez, Daniela</searchLink><relatesTo>1,2</relatesTo><i> dra.danielagarciam@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Escobedo-Berumen%2C+Lucía%22">Escobedo-Berumen, Lucía</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Carlos+Romo-Vázquez%2C+José%22">Carlos Romo-Vázquez, José</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Gerardo-del+Hoyo%2C+Moisés+Noé%22">Gerardo-del Hoyo, Moisés Noé</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Lezama-Armenta%2C+Andrés%22">Lezama-Armenta, Andrés</searchLink><relatesTo>2</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Revista+Mexicana+de+Pediatria%22">Revista Mexicana de Pediatria</searchLink>. ene/feb2026, Vol. 93 Issue 1, p13-19. 7p.
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  Data: <searchLink fieldCode="DE" term="%22ACUTE+kidney+failure%22">ACUTE kidney failure</searchLink><br /><searchLink fieldCode="DE" term="%22NEONATAL+intensive+care+units%22">NEONATAL intensive care units</searchLink><br /><searchLink fieldCode="DE" term="%22NEWBORN+infants%22">NEWBORN infants</searchLink><br /><searchLink fieldCode="DE" term="%22CLINICAL+decision+making%22">CLINICAL decision making</searchLink><br /><searchLink fieldCode="DE" term="%22SENSITIVITY+%26+specificity+%28Statistics%29%22">SENSITIVITY & specificity (Statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22CLINICAL+prediction+rules%22">CLINICAL prediction rules</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Introduction: acute kidney injury (AKI) in newborns is a frequent complication in the neonatal intensive care unit (NICU). Early identification is key to optimizing clinical management. Objective: to evaluate the usefulness of the STARZ score for predicting AKI in neonates hospitalized in a NICU. Material and methods: a retrospective study was conducted. The STARZ score was applied to all patients, and its diagnostic performance was compared against confirmed cases of AKI according to the KDIGO criteria adapted for neonates, considered the gold standard. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and area under the ROC curve were calculated. Results: 456 neonates were included, of whom 32 (7%) developed AKI. The STARZ score showed a sensitivity of 96.9%, specificity of 78.3%, PPV of 25.2%, and NPV of 99.7%. The area under the curve was 0.977. Conclusions: the STARZ score demonstrated high diagnostic performance for predicting AKI in neonates. Its application in the NICU could facilitate early detection of AKI, optimize renal monitoring, and improve clinical decision-making. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Introducción: la lesión renal aguda (LRA) en recién nacidos es una complicación frecuente en la unidad de cuidados intensivos neonatales (UCIN). Su identificación temprana es clave para optimizar el manejo clínico. Objetivo: evaluar la utilidad de la escala STARZ para predecir LRA en neonatos hospitalizados en una UCIN. Material y métodos: se realizó un estudio retrospectivo. Se aplicó la escala STARZ a todos los pacientes y se comparó su rendimiento diagnóstico frente a los casos confirmados de LRA según los criterios de KDIGO adaptados para neonatos, considerados como el estándar de oro. Se calculó sensibilidad, especificidad, valor predictivo positivo (VPP), valor predictivo negativo (VPN)y área bajo la curva ROC. Resultados: se incluyeron 456 neonatos, de los cuales 32 (7%) desarrollaron LRA. La escala STARZ presentó una sensibilidad de 96.9%, especificidad de 78.3%, VPP de 25.2% y VPN de 99.7%. El área bajo la curva fue de 0.977. Conclusiones: la escala STARZ demostró alto rendimiento diagnóstico para predecir LRA en neonatos. Su aplicación en UCIN podría facilitar una detección temprana de LRA, optimizar el monitoreo renal y mejorar la toma de decisiones clínicas. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Revista Mexicana de Pediatria is the property of Sociedad Mexicana de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.35366/123104
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        Text: Spanish
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      – SubjectFull: ACUTE kidney failure
        Type: general
      – SubjectFull: NEONATAL intensive care units
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      – SubjectFull: NEWBORN infants
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      – SubjectFull: CLINICAL decision making
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      – SubjectFull: SENSITIVITY & specificity (Statistics)
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      – SubjectFull: CLINICAL prediction rules
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    Titles:
      – TitleFull: Utilidad de la escala STARZ para predecir lesión renal aguda en recién nacidos atendidos en una Unidad de Cuidados Intensivos Neonatales.
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              Text: ene/feb2026
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              Y: 2026
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