Uso de diálisis de único paso con albúmina en paciente con falla hepática aguda por dengue: reporte de caso.

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Title: Uso de diálisis de único paso con albúmina en paciente con falla hepática aguda por dengue: reporte de caso.
Alternate Title: Use of single-pass albumin dialysis in a patient with acute liver failure due to dengue: A case report.
Authors: Carvajal, Carlos1 ccarvajal@hptu.org.co, Arias, Juan1, Torres, Santiago2
Source: Biomédica: Revista del Instituto Nacional de Salud. jun2026, Vol. 46 Issue 2, p195-202. 8p.
Subjects: LIVER failure, DENGUE, KIDNEY diseases, ARTIFICIAL respiration, THROMBOCYTOPENIA
Abstract (English): Dengue is the most common arboviral infection worldwide, and up to 5% of patients may develop severe forms with multiorgan involvement and an increased risk of death. We present the case of a 39-year-old woman from an endemic area, living in an urban setting, who presented with five days of fever associated with myalgias and vaginal bleeding. On admission, severe thrombocytopenia and acute hepatic and renal dysfunction were documented. Despite initial treatment with crystalloids, her condition progressively worsened, leading to acute liver failure and worsening acute kidney injury, requiring invasive mechanical ventilation, vasopressor support, and single-pass albumin dialysis plus continuous veno-venous hemodiafiltration. The patient showed clinical improvement with progressive recovery of liver and kidney function and was transferred to general hospitalization after 12 days in intensive care. This case highlights the potential usefulness of this therapy in patients with acute liver failure in settings without access to advanced liver support systems or when liver transplantation is contraindicated. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): El dengue es la infección arboviral más frecuente a nivel mundial y hasta el 5 % de los pacientes pueden desarrollar formas graves con compromiso multiorgánico y mayor riesgo de muerte. Se presenta el caso de una paciente de 39 años, procedente de zona endémica y residente en área urbana, que consultó por fiebre de cinco días asociada a mialgias y sangrado vaginal. Al ingreso se documentó trombocitopenia grave, disfunción hepática y disfunción renal. A pesar del tratamiento inicial con cristaloides, tuvo deterioro clínico progresivo de su enfermedad, lo que resultó en falla hepática aguda y progresión de la lesión renal aguda, con necesidad de iniciar soporte ventilatorio invasivo, vasopresores y terapia con diálisis de albúmina de único paso más hemodiafiltración veno-venosa continua. Hubo mejoría clínica con recuperación progresiva de la función hepática y renal, y fue trasladada a hospitalización después de doce días en cuidados intensivos. Este caso destaca la posible utilidad de esta terapia en pacientes con falla hepática aguda en sitios sin acceso a técnicas avanzadas de soporte hepático o cuando existe alguna contraindicación para el trasplante hepático. [ABSTRACT FROM AUTHOR]
Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
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  Data: Uso de diálisis de único paso con albúmina en paciente con falla hepática aguda por dengue: reporte de caso.
– Name: TitleAlt
  Label: Alternate Title
  Group: TiAlt
  Data: Use of single-pass albumin dialysis in a patient with acute liver failure due to dengue: A case report.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Carvajal%2C+Carlos%22">Carvajal, Carlos</searchLink><relatesTo>1</relatesTo><i> ccarvajal@hptu.org.co</i><br /><searchLink fieldCode="AR" term="%22Arias%2C+Juan%22">Arias, Juan</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Torres%2C+Santiago%22">Torres, Santiago</searchLink><relatesTo>2</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Biomédica%3A+Revista+del+Instituto+Nacional+de+Salud%22">Biomédica: Revista del Instituto Nacional de Salud</searchLink>. jun2026, Vol. 46 Issue 2, p195-202. 8p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22LIVER+failure%22">LIVER failure</searchLink><br /><searchLink fieldCode="DE" term="%22DENGUE%22">DENGUE</searchLink><br /><searchLink fieldCode="DE" term="%22KIDNEY+diseases%22">KIDNEY diseases</searchLink><br /><searchLink fieldCode="DE" term="%22ARTIFICIAL+respiration%22">ARTIFICIAL respiration</searchLink><br /><searchLink fieldCode="DE" term="%22THROMBOCYTOPENIA%22">THROMBOCYTOPENIA</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Dengue is the most common arboviral infection worldwide, and up to 5% of patients may develop severe forms with multiorgan involvement and an increased risk of death. We present the case of a 39-year-old woman from an endemic area, living in an urban setting, who presented with five days of fever associated with myalgias and vaginal bleeding. On admission, severe thrombocytopenia and acute hepatic and renal dysfunction were documented. Despite initial treatment with crystalloids, her condition progressively worsened, leading to acute liver failure and worsening acute kidney injury, requiring invasive mechanical ventilation, vasopressor support, and single-pass albumin dialysis plus continuous veno-venous hemodiafiltration. The patient showed clinical improvement with progressive recovery of liver and kidney function and was transferred to general hospitalization after 12 days in intensive care. This case highlights the potential usefulness of this therapy in patients with acute liver failure in settings without access to advanced liver support systems or when liver transplantation is contraindicated. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: El dengue es la infección arboviral más frecuente a nivel mundial y hasta el 5 % de los pacientes pueden desarrollar formas graves con compromiso multiorgánico y mayor riesgo de muerte. Se presenta el caso de una paciente de 39 años, procedente de zona endémica y residente en área urbana, que consultó por fiebre de cinco días asociada a mialgias y sangrado vaginal. Al ingreso se documentó trombocitopenia grave, disfunción hepática y disfunción renal. A pesar del tratamiento inicial con cristaloides, tuvo deterioro clínico progresivo de su enfermedad, lo que resultó en falla hepática aguda y progresión de la lesión renal aguda, con necesidad de iniciar soporte ventilatorio invasivo, vasopresores y terapia con diálisis de albúmina de único paso más hemodiafiltración veno-venosa continua. Hubo mejoría clínica con recuperación progresiva de la función hepática y renal, y fue trasladada a hospitalización después de doce días en cuidados intensivos. Este caso destaca la posible utilidad de esta terapia en pacientes con falla hepática aguda en sitios sin acceso a técnicas avanzadas de soporte hepático o cuando existe alguna contraindicación para el trasplante hepático. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.7705/biomedica.7682
    Languages:
      – Code: spa
        Text: Spanish
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 195
    Subjects:
      – SubjectFull: LIVER failure
        Type: general
      – SubjectFull: DENGUE
        Type: general
      – SubjectFull: KIDNEY diseases
        Type: general
      – SubjectFull: ARTIFICIAL respiration
        Type: general
      – SubjectFull: THROMBOCYTOPENIA
        Type: general
    Titles:
      – TitleFull: Uso de diálisis de único paso con albúmina en paciente con falla hepática aguda por dengue: reporte de caso.
        Type: main
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            NameFull: Carvajal, Carlos
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            NameFull: Arias, Juan
      – PersonEntity:
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            NameFull: Torres, Santiago
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            – D: 01
              M: 06
              Text: jun2026
              Type: published
              Y: 2026
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              Value: 01204157
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              Value: 46
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