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Analysis of Predictive Factors for Cognitive Function Improvement After tDCS Treatment in Patients With Post-stroke Cognitive Impairment.

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Title: Analysis of Predictive Factors for Cognitive Function Improvement After tDCS Treatment in Patients With Post-stroke Cognitive Impairment.
Authors: Li, Ting1, Lin, Jixin2, Zhang, Liya1, Wang, Xin1, Zhang, Jie1, Xu, Jing1, Ye, Qing1 yeqingc@163.com
Source: Actas Espanolas de Psiquiatria. 2026, Vol. 54 Issue 2, p362-368. 7p.
Subjects: Educational attainment, Disease duration, Cognition disorders, Transcranial direct current stimulation, Prognosis, Mini-Mental State Examination, Cognitive ability
Abstract: Objective: This study aims to identify predictive factors for significant cognitive improvement following transcranial direct current stimulation (tDCS) in patients with post-stroke cognitive impairment (PSCI), thereby providing evidence for individualized clinical intervention. Methods: A total of 123 patients with PSCI who received tDCS treatment were retrospectively enrolled. Based on changes in Mini-Mental State Examination (MMSE) scores, patients were classified into a cognitive improvement group (n = 61) and a non-improvement group (n = 62). Baseline clinical characteristics were collected, and activities of daily living were using the Modified Barthel Index (MBI). Univariate analyses were performed to compare differences between the two groups, and variables with statistical significance in univariate analysis were further entered into a multivariate logistic regression model to identify independent predictors of significant cognitive improvement following tDCS treatment. Results: The proportion of patients with a university education or above was significantly in the cognitive improvement group higher than in the non-improvement group (p < 0.001); whereas the proportion of patients with a history of stroke in the non-improvement group was significantly higher (p < 0.05). Patients in the cognitive improvement group had a significantly shorter disease duration compared to those in the non-improvement group (p < 0.05); meanwhile, a higher proportion of patients with Fazekas grade 0–1 was observed in the improvement group (p < 0.05). Results of the multivariate Logistic regression analysis indicated that educational level and disease duration were independent predictive factors for significant cognitive improvement after tDCS treatment (p < 0.05). Conclusion: PSCI patients with higher educational level and shorter disease duration have a better cognitive improvement effect following tDCS treatment. [ABSTRACT FROM AUTHOR]
Copyright of Actas Espanolas de Psiquiatria is the property of Maria Lopez-Ibor and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
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  Data: Objective: This study aims to identify predictive factors for significant cognitive improvement following transcranial direct current stimulation (tDCS) in patients with post-stroke cognitive impairment (PSCI), thereby providing evidence for individualized clinical intervention. Methods: A total of 123 patients with PSCI who received tDCS treatment were retrospectively enrolled. Based on changes in Mini-Mental State Examination (MMSE) scores, patients were classified into a cognitive improvement group (n = 61) and a non-improvement group (n = 62). Baseline clinical characteristics were collected, and activities of daily living were using the Modified Barthel Index (MBI). Univariate analyses were performed to compare differences between the two groups, and variables with statistical significance in univariate analysis were further entered into a multivariate logistic regression model to identify independent predictors of significant cognitive improvement following tDCS treatment. Results: The proportion of patients with a university education or above was significantly in the cognitive improvement group higher than in the non-improvement group (p &lt; 0.001); whereas the proportion of patients with a history of stroke in the non-improvement group was significantly higher (p &lt; 0.05). Patients in the cognitive improvement group had a significantly shorter disease duration compared to those in the non-improvement group (p &lt; 0.05); meanwhile, a higher proportion of patients with Fazekas grade 0–1 was observed in the improvement group (p &lt; 0.05). Results of the multivariate Logistic regression analysis indicated that educational level and disease duration were independent predictive factors for significant cognitive improvement after tDCS treatment (p &lt; 0.05). Conclusion: PSCI patients with higher educational level and shorter disease duration have a better cognitive improvement effect following tDCS treatment. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Actas Espanolas de Psiquiatria is the property of Maria Lopez-Ibor and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.62641/aep.v54i2.2161
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      – Code: eng
        Text: English
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        PageCount: 7
        StartPage: 362
    Subjects:
      – SubjectFull: Educational attainment
        Type: general
      – SubjectFull: Disease duration
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      – SubjectFull: Cognition disorders
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      – SubjectFull: Transcranial direct current stimulation
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      – SubjectFull: Mini-Mental State Examination
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      – SubjectFull: Cognitive ability
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      – TitleFull: Analysis of Predictive Factors for Cognitive Function Improvement After tDCS Treatment in Patients With Post-stroke Cognitive Impairment.
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              Text: 2026
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