Severity of Cognitive Impairment and Its Correlation With Depressive Symptoms and Influencing Factors in Elderly Patients With Chronic Diseases.
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| Title: | Severity of Cognitive Impairment and Its Correlation With Depressive Symptoms and Influencing Factors in Elderly Patients With Chronic Diseases. |
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| Authors: | Liu, Xing1, Ma, Wenxuan1, Wei, Xiaoyong1, Yang, Xiaoxia1, Ni, Xinli1 xinlini6@nyfy.com.cn |
| Source: | Actas Espanolas de Psiquiatria. 2026, Vol. 54 Issue 2, p369-379. 11p. |
| Subjects: | Cognition disorders, Mental depression, Hypertension, Older patients, Geriatric Depression Scale, Montreal Cognitive Assessment, Chronic diseases, Diabetes |
| Abstract: | Background: Elderly individuals frequently suffer from chronic underlying disease like hypertension and diabetes. These illnesses not only impair physical health but also show a close link to elevated rates of cognitive impairment and depressive symptoms. The mutual influence between these two issues can further diminish the quality of life of elderly patients. Nevertheless, there remains a shortage of systematic investigations into the cognitive-emotional relationship within this specific population. Methods: A total of 206 elderly patients with chronic underlying disease were enrolled retrospectively. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA). Depressive symptoms were evaluated via the 15-item Geriatric Depression Scale (GDS-15). To analyse the correlation between cognitive impairment and depressive symptoms, the Spearman correlation analysis, univariate analysis, and multivariate Logistic regression were employed. Results: Among the 206 patients, the primary chronic underlying diseases were hypertension (64.56%), diabetes mellitus (39.32%), coronary heart disease (27.67%), and chronic obstructive pulmonary disease (21.84%). Additionally, 45.15% of the patients had two or more chronic diseases. The prevalence of cognitive impairment stood at 49.51% (102 cases), while the prevalence of depressive symptoms was 40.78% (84 cases). No significant differences were observed in the prevalence of cognitive impairment and depressive symptoms among patients with different types of chronic diseases (all p > 0.05). Spearman correlation analysis revealed a significant negative correlation between MoCA scores and GDS-15 scores (r = –0.552, p < 0.001). Binary Logistic regression analysis indicated that factors such as body mass index ≥21.42 kg/m², number of chronic diseases ≥2.5, GDS-15 score ≥4.5 points, and Multidimensional Scale of Perceived Social Support score ≥52.5 were independent risk factors for moderate-to-severe cognitive impairment (all p < 0.05). Conclusions: The severity of cognitive impairment in elderly patients with comorbid chronic underlying diseases increases with the exacerbation of depressive symptoms. [ABSTRACT FROM AUTHOR] |
| Copyright of Actas Espanolas de Psiquiatria is the property of Maria Lopez-Ibor and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 194562697 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Severity of Cognitive Impairment and Its Correlation With Depressive Symptoms and Influencing Factors in Elderly Patients With Chronic Diseases. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Liu%2C+Xing%22">Liu, Xing</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ma%2C+Wenxuan%22">Ma, Wenxuan</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Wei%2C+Xiaoyong%22">Wei, Xiaoyong</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Yang%2C+Xiaoxia%22">Yang, Xiaoxia</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ni%2C+Xinli%22">Ni, Xinli</searchLink><relatesTo>1</relatesTo><i> xinlini6@nyfy.com.cn</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Actas+Espanolas+de+Psiquiatria%22">Actas Espanolas de Psiquiatria</searchLink>. 2026, Vol. 54 Issue 2, p369-379. 11p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Cognition+disorders%22">Cognition disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Hypertension%22">Hypertension</searchLink><br /><searchLink fieldCode="DE" term="%22Older+patients%22">Older patients</searchLink><br /><searchLink fieldCode="DE" term="%22Geriatric+Depression+Scale%22">Geriatric Depression Scale</searchLink><br /><searchLink fieldCode="DE" term="%22Montreal+Cognitive+Assessment%22">Montreal Cognitive Assessment</searchLink><br /><searchLink fieldCode="DE" term="%22Chronic+diseases%22">Chronic diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Diabetes%22">Diabetes</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background: Elderly individuals frequently suffer from chronic underlying disease like hypertension and diabetes. These illnesses not only impair physical health but also show a close link to elevated rates of cognitive impairment and depressive symptoms. The mutual influence between these two issues can further diminish the quality of life of elderly patients. Nevertheless, there remains a shortage of systematic investigations into the cognitive-emotional relationship within this specific population. Methods: A total of 206 elderly patients with chronic underlying disease were enrolled retrospectively. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA). Depressive symptoms were evaluated via the 15-item Geriatric Depression Scale (GDS-15). To analyse the correlation between cognitive impairment and depressive symptoms, the Spearman correlation analysis, univariate analysis, and multivariate Logistic regression were employed. Results: Among the 206 patients, the primary chronic underlying diseases were hypertension (64.56%), diabetes mellitus (39.32%), coronary heart disease (27.67%), and chronic obstructive pulmonary disease (21.84%). Additionally, 45.15% of the patients had two or more chronic diseases. The prevalence of cognitive impairment stood at 49.51% (102 cases), while the prevalence of depressive symptoms was 40.78% (84 cases). No significant differences were observed in the prevalence of cognitive impairment and depressive symptoms among patients with different types of chronic diseases (all p > 0.05). Spearman correlation analysis revealed a significant negative correlation between MoCA scores and GDS-15 scores (r = –0.552, p < 0.001). Binary Logistic regression analysis indicated that factors such as body mass index ≥21.42 kg/m², number of chronic diseases ≥2.5, GDS-15 score ≥4.5 points, and Multidimensional Scale of Perceived Social Support score ≥52.5 were independent risk factors for moderate-to-severe cognitive impairment (all p < 0.05). Conclusions: The severity of cognitive impairment in elderly patients with comorbid chronic underlying diseases increases with the exacerbation of depressive symptoms. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Actas Espanolas de Psiquiatria is the property of Maria Lopez-Ibor and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.62641/aep.v54i2.2166 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 11 StartPage: 369 Subjects: – SubjectFull: Cognition disorders Type: general – SubjectFull: Mental depression Type: general – SubjectFull: Hypertension Type: general – SubjectFull: Older patients Type: general – SubjectFull: Geriatric Depression Scale Type: general – SubjectFull: Montreal Cognitive Assessment Type: general – SubjectFull: Chronic diseases Type: general – SubjectFull: Diabetes Type: general Titles: – TitleFull: Severity of Cognitive Impairment and Its Correlation With Depressive Symptoms and Influencing Factors in Elderly Patients With Chronic Diseases. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Liu, Xing – PersonEntity: Name: NameFull: Ma, Wenxuan – PersonEntity: Name: NameFull: Wei, Xiaoyong – PersonEntity: Name: NameFull: Yang, Xiaoxia – PersonEntity: Name: NameFull: Ni, Xinli IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: 2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 11399287 Numbering: – Type: volume Value: 54 – Type: issue Value: 2 Titles: – TitleFull: Actas Espanolas de Psiquiatria Type: main |
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