Can the BES TEST help in assessing the risk of fragility fractures in patients with normal or osteopenic DEXA T-score?
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| Title: | Can the BES TEST help in assessing the risk of fragility fractures in patients with normal or osteopenic DEXA T-score? |
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| Authors: | Saviola, Gianantonio1 gianantonio.saviola@icsmaugeri.it, Abdi-Ali, Lul1, Zambarda, Clara1, Imperadori, Manuela2, Negro, Luigi2, Nicolosi, Alessandra3, Cosmi, Francesca4 |
| Source: | Journal of Osteoporosis & Mineral Metabolism / Revista de Osteoporosis y Metabolismo Mineral (Spanish edition). Apr-Jun2026, Vol. 18 Issue 2, p72-76. 5p. |
| Subjects: | Bone fractures, Bone density, Risk factors of fractures, Osteoporosis, Cancellous bone, Bone densitometry, Bone mechanics |
| Abstract: | Introduction: osteoporosis is characterized by reduced bone mass and deterioration of bone microarchitecture, leading to bone fragility. Dual-energy x-ray absorptiometry (DEXA), which measures bone mineral density (BMD), is considered the gold standard for the diagnosis of osteoporosis and osteopenia. However, BMD is only one among several fracture risk factors. Consequently, DEXA should be associated with fracture risk assessment tools (FRAX, DeFRA, or FRA-HS). Therefore, the development of additional tests capable of measuring trabecular structure properties (quality), rather than only bone density, is needed. Methods: the Bone Elastic Structure Test (BES TEST) is a CE-marked, registered software medical device that measures bone elastic response to loads. It is based on an internationally patented method using high-definition digital radiographs of the proximal epiphysis of 3 fingers to investigate the biomechanical functionality of the trabecular structure in terms of its contribution to bone strength. Results: the main objective of the study is to assess the reliability and performance of the BES TEST in patients with fragility fractures and normal or osteopenic DEXA T-scores. Previous data suggest that the BES TEST could be a useful complementary tool for completing fracture risk assessment. Therefore, we conducted a randomized controlled trial in which 50 female patients, divided into 2 groups (25 nonfractured and 25 recently fractured), underwent baseline lumbar spine, femoral, and femoral neck DEXA, together with a baseline BES TEST. Both examinations were repeated after 18 to 24 months, with the addition of spine morphometry. Conclusions: preliminary data confirm the reliability and reproducibility of both DEXA T-score and BSI T-score. The expected result is confirmation that BSI, associated with DEXA and FRAX-score or DeFRA-score, can help assess the risk of fragility fractures. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Osteoporosis & Mineral Metabolism / Revista de Osteoporosis y Metabolismo Mineral (Spanish edition) is the property of Ibanez y Plaza and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 194955594 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Can the BES TEST help in assessing the risk of fragility fractures in patients with normal or osteopenic DEXA T-score? – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Saviola%2C+Gianantonio%22">Saviola, Gianantonio</searchLink><relatesTo>1</relatesTo><i> gianantonio.saviola@icsmaugeri.it</i><br /><searchLink fieldCode="AR" term="%22Abdi-Ali%2C+Lul%22">Abdi-Ali, Lul</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Zambarda%2C+Clara%22">Zambarda, Clara</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Imperadori%2C+Manuela%22">Imperadori, Manuela</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Negro%2C+Luigi%22">Negro, Luigi</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Nicolosi%2C+Alessandra%22">Nicolosi, Alessandra</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Cosmi%2C+Francesca%22">Cosmi, Francesca</searchLink><relatesTo>4</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Osteoporosis+%26+Mineral+Metabolism+%2F+Revista+de+Osteoporosis+y+Metabolismo+Mineral+%28Spanish+edition%29%22">Journal of Osteoporosis & Mineral Metabolism / Revista de Osteoporosis y Metabolismo Mineral (Spanish edition)</searchLink>. Apr-Jun2026, Vol. 18 Issue 2, p72-76. 5p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Bone+fractures%22">Bone fractures</searchLink><br /><searchLink fieldCode="DE" term="%22Bone+density%22">Bone density</searchLink><br /><searchLink fieldCode="DE" term="%22Risk+factors+of+fractures%22">Risk factors of fractures</searchLink><br /><searchLink fieldCode="DE" term="%22Osteoporosis%22">Osteoporosis</searchLink><br /><searchLink fieldCode="DE" term="%22Cancellous+bone%22">Cancellous bone</searchLink><br /><searchLink fieldCode="DE" term="%22Bone+densitometry%22">Bone densitometry</searchLink><br /><searchLink fieldCode="DE" term="%22Bone+mechanics%22">Bone mechanics</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Introduction: osteoporosis is characterized by reduced bone mass and deterioration of bone microarchitecture, leading to bone fragility. Dual-energy x-ray absorptiometry (DEXA), which measures bone mineral density (BMD), is considered the gold standard for the diagnosis of osteoporosis and osteopenia. However, BMD is only one among several fracture risk factors. Consequently, DEXA should be associated with fracture risk assessment tools (FRAX, DeFRA, or FRA-HS). Therefore, the development of additional tests capable of measuring trabecular structure properties (quality), rather than only bone density, is needed. Methods: the Bone Elastic Structure Test (BES TEST) is a CE-marked, registered software medical device that measures bone elastic response to loads. It is based on an internationally patented method using high-definition digital radiographs of the proximal epiphysis of 3 fingers to investigate the biomechanical functionality of the trabecular structure in terms of its contribution to bone strength. Results: the main objective of the study is to assess the reliability and performance of the BES TEST in patients with fragility fractures and normal or osteopenic DEXA T-scores. Previous data suggest that the BES TEST could be a useful complementary tool for completing fracture risk assessment. Therefore, we conducted a randomized controlled trial in which 50 female patients, divided into 2 groups (25 nonfractured and 25 recently fractured), underwent baseline lumbar spine, femoral, and femoral neck DEXA, together with a baseline BES TEST. Both examinations were repeated after 18 to 24 months, with the addition of spine morphometry. Conclusions: preliminary data confirm the reliability and reproducibility of both DEXA T-score and BSI T-score. The expected result is confirmation that BSI, associated with DEXA and FRAX-score or DeFRA-score, can help assess the risk of fragility fractures. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Osteoporosis & Mineral Metabolism / Revista de Osteoporosis y Metabolismo Mineral (Spanish edition) is the property of Ibanez y Plaza and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.20960/RevOsteoporosMetabMiner.00106 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 72 Subjects: – SubjectFull: Bone fractures Type: general – SubjectFull: Bone density Type: general – SubjectFull: Risk factors of fractures Type: general – SubjectFull: Osteoporosis Type: general – SubjectFull: Cancellous bone Type: general – SubjectFull: Bone densitometry Type: general – SubjectFull: Bone mechanics Type: general Titles: – TitleFull: Can the BES TEST help in assessing the risk of fragility fractures in patients with normal or osteopenic DEXA T-score? Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Saviola, Gianantonio – PersonEntity: Name: NameFull: Abdi-Ali, Lul – PersonEntity: Name: NameFull: Zambarda, Clara – PersonEntity: Name: NameFull: Imperadori, Manuela – PersonEntity: Name: NameFull: Negro, Luigi – PersonEntity: Name: NameFull: Nicolosi, Alessandra – PersonEntity: Name: NameFull: Cosmi, Francesca IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: Apr-Jun2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 1889836X Numbering: – Type: volume Value: 18 – Type: issue Value: 2 Titles: – TitleFull: Journal of Osteoporosis & Mineral Metabolism / Revista de Osteoporosis y Metabolismo Mineral (Spanish edition) Type: main |
| ResultId | 1 |
