Microorganismos asociados a infecciones endodonticas: factores de virulencia, resistencia y persistencia.
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| Title: | Microorganismos asociados a infecciones endodonticas: factores de virulencia, resistencia y persistencia. |
|---|---|
| Alternate Title: | Microorganisms associated with endodontic infections: virulence, resistance and persistence factors. |
| Authors: | Barrera, D. Paula Valentina1, Navarrete, O. Jeannette1, Aguilera, R. Sandra E.1, Cruz, B. Claudia Andrea1, Santos, R. Paola A.1 |
| Source: | NOVA: Publicación Científica en Ciencias Biomédicas. ene-jun2026, Vol. 24 Issue 46, p179-201. 23p. |
| Subjects: | Drug resistance in microorganisms, Microbial virulence, Microrobots, Biofilms, Dental pulp diseases, Antimicrobial peptides, Molecular diagnosis, Microorganisms |
| Abstract (English): | Introduction. Endodontic root canal infections, caused by microbial colonization following pulp necrosis, are common pathologies caused by bacteria, fungi, archaea, and viruses. However, little is known about the virulence, resistance, and persistence factors of these biological agents. Objective. To analyze the microbiological aspects of virulence, resistance, and persistence of the agents involved in endodontic infections. Methodology. Systematic review of articles on endodontic infections, microorganisms involved, and characteristics of virulence, resistance, and persistence. Results. Among the microorganisms responsible for primary infections are Fusobacterium nucleatum, Campylobacter rectus, Tannerella forsythia, Prevotella spp., Porphyromonas spp., and Treponema spp. Streptococcus, Enterococcus, Peptostreptococcus, and Actinomyces are notable among secondary infections. In Colombia, the prevalence of endodontic periodontitis is 51.6%, with a higher frequency in women. Molecular diagnostics have proven advantageous in the early detection of pathogens, with pyrosequencing being the most efficient test compared to traditional methodologies. Conclusion. The increase in antimicrobial resistance and biofilm formation in root canals raises the need for therapeutic alternatives. In this context, antimicrobial peptides emerge as a promising option due to their antimicrobial and anti-biofilm effect, contributing to the containment of bacterial resistance. Likewise, microrobotics offers potential support in the removal of biofilms in root canals. This review constitutes a relevant contribution to future research and the development of new intervention strategies in this disciplinary field. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Introducción. Las infecciones endodónticas del conducto radicular, originadas tras necrosis pulpar por colonización microbiana, son patologías comunes causadas por bacterias, hongos, arqueas y virus. Sin embargo, poco se conoce sobre los factores de virulencia, resistencia y persistencia de estos agentes biológicos. Objetivo. Analizar los aspectos microbiológicos de virulencia, resistencia y persistencia de los agentes involucrados en infecciones endodónticas. Metodología. Revisión sistemática de artículos sobre infecciones endodónticas, microorganismos implicados y características de virulencia, resistencia y persistencia. Resultados. Entre los microorganismos responsables de infecciones primarias se encuentran Fusobacterium nucleatum, Campylobacter rectus, Tannerella forsythia, Prevotella spp., Porphyromonas spp. y Treponema spp. En las infecciones secundarias destacan Streptococcus, Enterococcus, Peptostreptococcus y Actinomyces. En Colombia, la prevalencia de periodontitis endodóntica es del 51,6%, con mayor frecuencia en mujeres. El diagnóstico molecular ha demostrado ventajas en la detección temprana de los patógenos, siendo la pirosecuenciación la prueba más eficiente en comparación con las metodologías tradicionales. Conclusión. El incremento en la resistencia antimicrobiana y la formación de biopelícula en los conductos radiculares plantea la necesidad de alternativas terapéuticas. En este contexto, los péptidos antimicrobianos surgen como una opción prometedora por su efecto antimicrobiano y antibiopelícula, contribuyendo a la contención de la resistencia bacteriana. Asimismo, la microrrobótica ofrece un apoyo potencial en la eliminación de biopelículas en los conductos radiculares. Esta revisión constituye un aporte relevante para futuras investigaciones y el desarrollo de nuevas estrategias de intervención en este campo disciplinar. [ABSTRACT FROM AUTHOR] |
| Copyright of NOVA: Publicación Científica en Ciencias Biomédicas is the property of Universidad Colegio Mayor de Cundinamarca and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 195078229 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Microorganismos asociados a infecciones endodonticas: factores de virulencia, resistencia y persistencia. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Microorganisms associated with endodontic infections: virulence, resistance and persistence factors. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Barrera%2C+D%2E+Paula+Valentina%22">Barrera, D. Paula Valentina</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Navarrete%2C+O%2E+Jeannette%22">Navarrete, O. Jeannette</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Aguilera%2C+R%2E+Sandra+E%2E%22">Aguilera, R. Sandra E.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Cruz%2C+B%2E+Claudia+Andrea%22">Cruz, B. Claudia Andrea</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Santos%2C+R%2E+Paola+A%2E%22">Santos, R. Paola A.</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22NOVA%3A+Publicación+Científica+en+Ciencias+Biomédicas%22">NOVA: Publicación Científica en Ciencias Biomédicas</searchLink>. ene-jun2026, Vol. 24 Issue 46, p179-201. 23p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Drug+resistance+in+microorganisms%22">Drug resistance in microorganisms</searchLink><br /><searchLink fieldCode="DE" term="%22Microbial+virulence%22">Microbial virulence</searchLink><br /><searchLink fieldCode="DE" term="%22Microrobots%22">Microrobots</searchLink><br /><searchLink fieldCode="DE" term="%22Biofilms%22">Biofilms</searchLink><br /><searchLink fieldCode="DE" term="%22Dental+pulp+diseases%22">Dental pulp diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Antimicrobial+peptides%22">Antimicrobial peptides</searchLink><br /><searchLink fieldCode="DE" term="%22Molecular+diagnosis%22">Molecular diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Microorganisms%22">Microorganisms</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Introduction. Endodontic root canal infections, caused by microbial colonization following pulp necrosis, are common pathologies caused by bacteria, fungi, archaea, and viruses. However, little is known about the virulence, resistance, and persistence factors of these biological agents. Objective. To analyze the microbiological aspects of virulence, resistance, and persistence of the agents involved in endodontic infections. Methodology. Systematic review of articles on endodontic infections, microorganisms involved, and characteristics of virulence, resistance, and persistence. Results. Among the microorganisms responsible for primary infections are Fusobacterium nucleatum, Campylobacter rectus, Tannerella forsythia, Prevotella spp., Porphyromonas spp., and Treponema spp. Streptococcus, Enterococcus, Peptostreptococcus, and Actinomyces are notable among secondary infections. In Colombia, the prevalence of endodontic periodontitis is 51.6%, with a higher frequency in women. Molecular diagnostics have proven advantageous in the early detection of pathogens, with pyrosequencing being the most efficient test compared to traditional methodologies. Conclusion. The increase in antimicrobial resistance and biofilm formation in root canals raises the need for therapeutic alternatives. In this context, antimicrobial peptides emerge as a promising option due to their antimicrobial and anti-biofilm effect, contributing to the containment of bacterial resistance. Likewise, microrobotics offers potential support in the removal of biofilms in root canals. This review constitutes a relevant contribution to future research and the development of new intervention strategies in this disciplinary field. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Introducción. Las infecciones endodónticas del conducto radicular, originadas tras necrosis pulpar por colonización microbiana, son patologías comunes causadas por bacterias, hongos, arqueas y virus. Sin embargo, poco se conoce sobre los factores de virulencia, resistencia y persistencia de estos agentes biológicos. Objetivo. Analizar los aspectos microbiológicos de virulencia, resistencia y persistencia de los agentes involucrados en infecciones endodónticas. Metodología. Revisión sistemática de artículos sobre infecciones endodónticas, microorganismos implicados y características de virulencia, resistencia y persistencia. Resultados. Entre los microorganismos responsables de infecciones primarias se encuentran Fusobacterium nucleatum, Campylobacter rectus, Tannerella forsythia, Prevotella spp., Porphyromonas spp. y Treponema spp. En las infecciones secundarias destacan Streptococcus, Enterococcus, Peptostreptococcus y Actinomyces. En Colombia, la prevalencia de periodontitis endodóntica es del 51,6%, con mayor frecuencia en mujeres. El diagnóstico molecular ha demostrado ventajas en la detección temprana de los patógenos, siendo la pirosecuenciación la prueba más eficiente en comparación con las metodologías tradicionales. Conclusión. El incremento en la resistencia antimicrobiana y la formación de biopelícula en los conductos radiculares plantea la necesidad de alternativas terapéuticas. En este contexto, los péptidos antimicrobianos surgen como una opción prometedora por su efecto antimicrobiano y antibiopelícula, contribuyendo a la contención de la resistencia bacteriana. Asimismo, la microrrobótica ofrece un apoyo potencial en la eliminación de biopelículas en los conductos radiculares. Esta revisión constituye un aporte relevante para futuras investigaciones y el desarrollo de nuevas estrategias de intervención en este campo disciplinar. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of NOVA: Publicación Científica en Ciencias Biomédicas is the property of Universidad Colegio Mayor de Cundinamarca and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 23 StartPage: 179 Subjects: – SubjectFull: Drug resistance in microorganisms Type: general – SubjectFull: Microbial virulence Type: general – SubjectFull: Microrobots Type: general – SubjectFull: Biofilms Type: general – SubjectFull: Dental pulp diseases Type: general – SubjectFull: Antimicrobial peptides Type: general – SubjectFull: Molecular diagnosis Type: general – SubjectFull: Microorganisms Type: general Titles: – TitleFull: Microorganismos asociados a infecciones endodonticas: factores de virulencia, resistencia y persistencia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Barrera, D. Paula Valentina – PersonEntity: Name: NameFull: Navarrete, O. Jeannette – PersonEntity: Name: NameFull: Aguilera, R. Sandra E. – PersonEntity: Name: NameFull: Cruz, B. Claudia Andrea – PersonEntity: Name: NameFull: Santos, R. Paola A. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: ene-jun2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 17942470 Numbering: – Type: volume Value: 24 – Type: issue Value: 46 Titles: – TitleFull: NOVA: Publicación Científica en Ciencias Biomédicas Type: main |
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