Calidad de vida relacionada con la salud en niños, niñas y adolescentes con enfermedad inflamatoria intestinal.
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| Title: | Calidad de vida relacionada con la salud en niños, niñas y adolescentes con enfermedad inflamatoria intestinal. |
|---|---|
| Alternate Title: | Health-related quality of life in children and adolescents with inflammatory bowel disease. |
| Authors: | Maurelia, E. Eduardo1 eduardomaureliae@gmail.com, Villanueva, C. Mónica2, Faúndez, H. Rossana2, Leyton, D. Barbaba3, González, Y. Mónica4, Muñoz F., María Paz5, Peña, Z. Rubén6 |
| Source: | Andes Pediatrica. may/jun2026, Vol. 97 Issue 3, p462-468. 7p. |
| Subjects: | Quality of life, Inflammatory bowel diseases, Crohn's disease, School children, Child patients, Teenagers, Ulcerative colitis, Biotherapy |
| Abstract (English): | Inflammatory Bowel Disease (IBD) is known to affect health-related quality of life (HRQoL), but the determining factors in pediatric patients remain unclear. Objective: To describe HRQoL in IBD patients and assess its relationship with demographic and clinical factors. Patients and Method: Multicenter cross-sectional study conducted in Santiago, Chile. It included patients aged 8 to 18 years, with at least 6 months of diagnosis, under outpatient follow-up, and able to independently complete the questionnaire. The IMPACT-III questionnaire was used, with higher scores (maximum = 100) indicating better HRQoL, along with a clinical and demographic survey. Results: The study included 39 patients, with a mean age of 13.7 years. 23 (59%) were female, 33 (84%) had ulcerative colitis, and 6 (16%) had Crohn’s disease. 16 (41%) were on biologic therapy. 28 patients were in clinical remission, 10 had mild disease activity, and 1 had moderate disease activity. The mean HRQoL score was 67.02 (SD ± 14.87), with emotional functioning being the most affected domain. Males had an HRQoL of 71 vs 63 (p = 0.08) compared to females, with a significant difference in the well-being domain. No correlations were found between disease duration, fecal calprotectin levels, and HRQoL. There was no difference between patients with or without biologic therapy. Conclusion: These findings suggest the need for targeted interventions to improve HRQoL in pediatric IBD patients, especially in females. Further research is warranted to explore the underlying factors contributing to this disparity and to develop personalized treatment strategies. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Se sabe que la enfermedad inflamatoria intestinal (EII) afecta la calidad de vida relacionada con la salud (CVRS), pero los factores determinantes en pacientes pediátricos aún no están claros. Objetivo: Describir la CVRS en pacientes con EII y evaluar su relación con factores demográficos y clínicos. Pacientes y Método: Estudio multicéntrico transversal en Santiago de Chile. Incluyó pacientes de 8 a 18 años, con al menos 6 meses de diagnóstico, en seguimiento ambulatorio y con capacidad de responder la encuesta de forma independiente. Se utilizó el cuestionario IMPACT-III, puntajes más altos (máximo = 100) indican mejor CVRS, junto con una encuesta clínica y demográfica. Resultados: El estudio incluyó 39 pacientes, edad promedio 13,7 años. 23 (59%) sexo femenino, 33 (84%) tenía colitis ulcerosa, 6 (16%) enfermedad de Crohn. 16 (41%) en tratamiento biológico. 28 pacientes estaban en remisión clínica, 10 con actividad leve y 1 con actividad moderada. Puntaje promedio de CVRS fue 67,02 (DS ± 14,87), siendo el funcionamiento emocional el dominio más afectado. Los varones presentaron una CVRS de 71vs 63 (p = 0,08) en comparación con las mujeres, con una diferencia significativa en el dominio bienestar. No se encontraron correlaciones entre el tiempo de diagnóstico, la calprotectina fecal y la CVRS. No hubo diferencia entre los pacientes con y sin tratamiento biológico. Conclusión: Estos hallazgos sugieren la necesidad de intervenciones específicas para mejorar la CVRS en pacientes con EII pediátrica, especialmente en mujeres. Se justifican investigaciones para explorar los factores subyacentes que contribuyen a esta disparidad y desarrollar estrategias de tratamiento personalizadas. [ABSTRACT FROM AUTHOR] |
| Copyright of Andes Pediatrica is the property of Revista Chilena de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 195298126 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Calidad de vida relacionada con la salud en niños, niñas y adolescentes con enfermedad inflamatoria intestinal. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Health-related quality of life in children and adolescents with inflammatory bowel disease. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Maurelia%2C+E%2E+Eduardo%22">Maurelia, E. Eduardo</searchLink><relatesTo>1</relatesTo><i> eduardomaureliae@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Villanueva%2C+C%2E+Mónica%22">Villanueva, C. Mónica</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Faúndez%2C+H%2E+Rossana%22">Faúndez, H. Rossana</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Leyton%2C+D%2E+Barbaba%22">Leyton, D. Barbaba</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22González%2C+Y%2E+Mónica%22">González, Y. Mónica</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Muñoz+F%2E%2C+María+Paz%22">Muñoz F., María Paz</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Peña%2C+Z%2E+Rubén%22">Peña, Z. Rubén</searchLink><relatesTo>6</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Andes+Pediatrica%22">Andes Pediatrica</searchLink>. may/jun2026, Vol. 97 Issue 3, p462-468. 7p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink><br /><searchLink fieldCode="DE" term="%22Inflammatory+bowel+diseases%22">Inflammatory bowel diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Crohn's+disease%22">Crohn's disease</searchLink><br /><searchLink fieldCode="DE" term="%22School+children%22">School children</searchLink><br /><searchLink fieldCode="DE" term="%22Child+patients%22">Child patients</searchLink><br /><searchLink fieldCode="DE" term="%22Teenagers%22">Teenagers</searchLink><br /><searchLink fieldCode="DE" term="%22Ulcerative+colitis%22">Ulcerative colitis</searchLink><br /><searchLink fieldCode="DE" term="%22Biotherapy%22">Biotherapy</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Inflammatory Bowel Disease (IBD) is known to affect health-related quality of life (HRQoL), but the determining factors in pediatric patients remain unclear. Objective: To describe HRQoL in IBD patients and assess its relationship with demographic and clinical factors. Patients and Method: Multicenter cross-sectional study conducted in Santiago, Chile. It included patients aged 8 to 18 years, with at least 6 months of diagnosis, under outpatient follow-up, and able to independently complete the questionnaire. The IMPACT-III questionnaire was used, with higher scores (maximum = 100) indicating better HRQoL, along with a clinical and demographic survey. Results: The study included 39 patients, with a mean age of 13.7 years. 23 (59%) were female, 33 (84%) had ulcerative colitis, and 6 (16%) had Crohn’s disease. 16 (41%) were on biologic therapy. 28 patients were in clinical remission, 10 had mild disease activity, and 1 had moderate disease activity. The mean HRQoL score was 67.02 (SD ± 14.87), with emotional functioning being the most affected domain. Males had an HRQoL of 71 vs 63 (p = 0.08) compared to females, with a significant difference in the well-being domain. No correlations were found between disease duration, fecal calprotectin levels, and HRQoL. There was no difference between patients with or without biologic therapy. Conclusion: These findings suggest the need for targeted interventions to improve HRQoL in pediatric IBD patients, especially in females. Further research is warranted to explore the underlying factors contributing to this disparity and to develop personalized treatment strategies. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Se sabe que la enfermedad inflamatoria intestinal (EII) afecta la calidad de vida relacionada con la salud (CVRS), pero los factores determinantes en pacientes pediátricos aún no están claros. Objetivo: Describir la CVRS en pacientes con EII y evaluar su relación con factores demográficos y clínicos. Pacientes y Método: Estudio multicéntrico transversal en Santiago de Chile. Incluyó pacientes de 8 a 18 años, con al menos 6 meses de diagnóstico, en seguimiento ambulatorio y con capacidad de responder la encuesta de forma independiente. Se utilizó el cuestionario IMPACT-III, puntajes más altos (máximo = 100) indican mejor CVRS, junto con una encuesta clínica y demográfica. Resultados: El estudio incluyó 39 pacientes, edad promedio 13,7 años. 23 (59%) sexo femenino, 33 (84%) tenía colitis ulcerosa, 6 (16%) enfermedad de Crohn. 16 (41%) en tratamiento biológico. 28 pacientes estaban en remisión clínica, 10 con actividad leve y 1 con actividad moderada. Puntaje promedio de CVRS fue 67,02 (DS ± 14,87), siendo el funcionamiento emocional el dominio más afectado. Los varones presentaron una CVRS de 71vs 63 (p = 0,08) en comparación con las mujeres, con una diferencia significativa en el dominio bienestar. No se encontraron correlaciones entre el tiempo de diagnóstico, la calprotectina fecal y la CVRS. No hubo diferencia entre los pacientes con y sin tratamiento biológico. Conclusión: Estos hallazgos sugieren la necesidad de intervenciones específicas para mejorar la CVRS en pacientes con EII pediátrica, especialmente en mujeres. Se justifican investigaciones para explorar los factores subyacentes que contribuyen a esta disparidad y desarrollar estrategias de tratamiento personalizadas. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Andes Pediatrica is the property of Revista Chilena de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.32641/andespediatr.v97i3.5786 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 7 StartPage: 462 Subjects: – SubjectFull: Quality of life Type: general – SubjectFull: Inflammatory bowel diseases Type: general – SubjectFull: Crohn's disease Type: general – SubjectFull: School children Type: general – SubjectFull: Child patients Type: general – SubjectFull: Teenagers Type: general – SubjectFull: Ulcerative colitis Type: general – SubjectFull: Biotherapy Type: general Titles: – TitleFull: Calidad de vida relacionada con la salud en niños, niñas y adolescentes con enfermedad inflamatoria intestinal. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Maurelia, E. Eduardo – PersonEntity: Name: NameFull: Villanueva, C. Mónica – PersonEntity: Name: NameFull: Faúndez, H. Rossana – PersonEntity: Name: NameFull: Leyton, D. Barbaba – PersonEntity: Name: NameFull: González, Y. Mónica – PersonEntity: Name: NameFull: Muñoz F., María Paz – PersonEntity: Name: NameFull: Peña, Z. Rubén IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: may/jun2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 24526045 Numbering: – Type: volume Value: 97 – Type: issue Value: 3 Titles: – TitleFull: Andes Pediatrica Type: main |
| ResultId | 1 |
