Bibliographic Details
| Title: |
Raquitismo nutricional y pandemia COVID. |
| Alternate Title: |
Nutritional rickets and COVID pandemic. |
| Authors: |
Soto, Julio1,2,3 soto.jb@gmail.com, Hu, Pamela3, Bronson, Mary3, León, Alba4, Carpenter, Thomas O.3 |
| Source: |
Andes Pediatrica. may/jun2026, Vol. 97 Issue 3, p477-487. 11p. |
| Subjects: |
Vitamin D deficiency, Deficiency diseases, Racial differences, COVID-19 pandemic, Pediatrics, Epidemiology, Breastfeeding |
| Abstract (English): |
Nutritional rickets is caused by vitamin D and/or calcium deficiency. It was proposed that during the COVID-19 pandemic, the incidence of this condition would increase. Objective: To describe the clinical characteristics of vitamin D-deficiency rickets cases presented one year before the pandemic (2019) and during its last year (2022), and to compare its frequency between both periods. Patients and Method: Retrospective case series. The study included all patients under 5 years of age with a diagnosis of vitamin D-deficiency rickets, seen at the Yale New Haven Health System, Connecticut, at 41° latitude, United States, during the described periods, excluding those with vitamin D deficiency without rickets and those with rickets of other etiologies. Results: We report six cases of rickets: one in 2019 and five in 2022. All were African American children with a median age of 20 months (interquartile range 12-16) and a history of prolonged breastfeeding with low vitamin D intake and inadequate supplementation, as well as poor intake of calcium-rich foods due to food allergy and/or avoidant/restrictive eating disorder. Five cases showed elevated serum alkaline phosphatase activity, and four of them presented increased parathyroid hormone and decreased 25 OH vitamin D concentrations. The radiological finding of metaphyseal widening and fraying was found in all cases. The prevalence was 0.027% and 0.020% for 2019 and 2022, respectively (p = 0.005). Conclusion: Factors such as living at high latitudes, dark skin, and inadequate intake of calcium and vitamin D were the main elements linked to the development of nutritional rickets during the COVID-19 pandemic. No increase in frequency was observed during this period. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
El raquitismo nutricional es producido por deficiencia de vitamina D y/o calcio. Se hipotetizó un aumento de su frecuencia durante la pandemia de COVID-19. Objetivo: Describir las características clínicas de casos de raquitismo por deficiencia de vitamina D presentados un año antes de la pandemia (2019) y durante el último año de ésta (2022) y comparar la frecuencia entre ambos períodos. Pacientes y Método: Serie clínica retrospectiva. Se incluyeron todos los menores de 5 años evaluados en el Sistema de Salud de Yale New Haven, Connecticut, Latitud 41º, Estados Unidos, durante los períodos descritos con diagnósticos de raquitismo o deficiencia de vitamina D, excluyendo la deficiencia de vitamina D sin raquitismo y raquitismo de etiología diferente. Resultados: Reportamos seis casos: uno el 2019 y cinco el 2022. Todos afroamericanos, mediana de edad de 20 meses (Rango intercuartílico 12-16), con antecedentes de lactancia materna prolongada, baja ingesta e inadecuada suplementación de vitamina D, deficiente ingesta de alimentos con calcio debido a alergia alimentaria y/o trastorno alimentario evitativo/restrictivo. Cinco pacientes presentaron niveles séricos elevados de fosfatasas alcalinas, asociado en 4 casos a aumento de paratohormona y disminución de 25-OH vitamina D. El hallazgo radiológico de ensanchamiento y deshilachamiento metafisario estuvo presente en todos los casos. La frecuencia fue 0,027% y 0,020% para 2019 y 2022, respectivamente (p = 0,005). Conclusión: Factores como residencia a latitud alta, piel oscura, inapropiado cumplimiento de los requerimientos nutricionales de calcio y vitamina D fueron los principales elementos vinculados al desarrollo de raquitismo nutricional en la proximidad de la pandemia de COVID-19. No se evidenció aumento de incidencia durante este periodo. [ABSTRACT FROM AUTHOR] |
|
Copyright of Andes Pediatrica is the property of Revista Chilena de Pediatria and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
MedicLatina |
