NEUROCOGNITIVE HETEROGENEITY IN BORDERLINE PERSONALITY DISORDER: THE ROLE OF CHILDHOOD SEXUAL ABUSE.
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| Title: | NEUROCOGNITIVE HETEROGENEITY IN BORDERLINE PERSONALITY DISORDER: THE ROLE OF CHILDHOOD SEXUAL ABUSE. |
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| Alternate Title: | HETEROGENEIDAD NEUROCOGNITIVA EN EL TRASTORNO LÍMITE DE LA PERSONALIDAD: EL PAPEL DEL ABUSO SEXUAL INFANTIL. HETEROGENEIDADE NEUROCOGNITIVA NO TRANSTORNO DE PERSONALIDADE LIMÍTROFE: O PAPEL DO ABUSO SEXUAL INFANTIL. |
| Authors: | Cabrera, Horus Laffite1,2 hlafcab@gmail.com, Rodríguez-Otero, Fernando2, Alonso-Sosa, Raquel1,2, Martínez-Huidobro, María F.2, Hernández-Fleta, José L.1,2, Díaz-Garrido, Juan Antonio1,2,3 |
| Source: | Panamerican Journal of Neuropsychology / Cuadernos de Neuropsicología. may-ago2026, Vol. 20 Issue 2, p93-111. 19p. |
| Subjects: | Child sexual abuse, Borderline personality disorder, Cognitive flexibility, Neurobehavioral disorders, Memory disorders, Attention-deficit hyperactivity disorder, Trauma-informed care, Impulsive personality |
| Abstract (English): | Childhood sexual abuse (CSA) is strongly associated with borderline personality disorder (BPD). This cross-sectional study investigated clinical and neurocognitive differences in 193 women aged 20 to 39 years diagnosed with BPD, comparing those with a history of CSA (n = 78) and those without (n = 115). Participants completed standardized psychometric and neuropsychological assessments focused on impulsivity, core BPD symptoms, and cognitive functioning. Women with CSA showed greater clinical severity, including higher rates of self-harm, suicide attempts, dissociative and psychotic symptoms, along with elevated impulsivity and attention-deficit/hyperactivity disorder (ADHD)–related traits. Neuropsychological testing revealed significant deficits in attention, processing speed, and cognitive flexibility, along with lower performance on Stroop tasks assessing divided attention and interference control. While working memory and verbal fluency differences remained within normative ranges, age-stratified analysis revealed marked long-term memory impairments in the CSA group aged 30–39. These results suggest that neurocognitive deficits in BPD are not universal but may reflect the cumulative impact of early trauma and age. Trauma-informed assessment and tailored cognitive interventions may support more accurate profiling and inform tailored therapeutic strategies in this highrisk subgroup. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | El abuso sexual infantil (ASI) se asocia de forma consistente con el trastorno límite de la personalidad (TLP). Este estudio transversal examinó las diferencias clínicas y neurocognitivas en 193 mujeres de entre 20 y 39 años con diagnóstico de TLP, comparando aquellas con antecedentes de ASI (n = 78) y aquellas sin tales antecedentes (n = 115). Las participantes completaron evaluaciones psicométricas y neuropsicológicas estandarizadas centradas en impulsividad, sintomatología propia del TLP y funcionamiento cognitivo. Las mujeres con ASI mostraron una mayor gravedad clínica, incluyendo tasas más elevadas de autolesiones, intentos de suicidio, síntomas disociativos y psicóticos, así como una mayor impulsividad y presencia de rasgos relacionados con el trastorno por déficit de atención con hiperactividad (TDAH). A nivel neurocognitivo, se observaron déficits significativos en atención, velocidad de procesamiento y flexibilidad cognitiva, así como un rendimiento reducido en tareas que requerían atención dividida y control de interferencias. Si bien las diferencias en memoria de trabajo y fluidez verbal se mantuvieron dentro de los rangos normativos, los análisis estratificados por edad revelaron alteraciones marcadas en la memoria a largo plazo en el grupo con ASI entre los 30 y 39 años. Estos hallazgos sugieren que los déficits neurocognitivos en el TLP no son universales, sino que podrían reflejar el impacto acumulativo del trauma temprano y la vulnerabilidad asociada a la edad. La evaluación informada por el trauma y el diseño de intervenciones cognitivas personalizadas podrían contribuir a mejorar la precisión diagnóstica y la eficacia terapéutica en este subgrupo de alto riesgo. [ABSTRACT FROM AUTHOR] |
| Abstract (Portuguese): | O abuso sexual infantil (ASI) está fortemente associado ao transtorno de personalidade limítrofe (TPL). Este estudo transversal investigou diferenças clínicas e neurocognitivas em 193 mulheres, com idades entre 20 e 39 anos, diagnosticadas com TPL, comparando aquelas com histórico de ASI (n = 78) e aquelas sem esse antecedente (n = 115). As participantes realizaram avaliações psicométricas e neuropsicológicas padronizadas, com foco na impulsividade, nos sintomas centrais do TPL e no funcionamento cognitivo. As mulheres com ASI apresentaram maior gravidade clínica, incluindo taxas mais elevadas de autolesão, tentativas de suicídio, sintomas dissociativos e psicóticos, bem como maior impulsividade e presença de características associadas ao transtorno de déficit de atenção/hiperatividade (TDAH). A avaliação neuropsicológica revelou déficits significativos em atenção, velocidade de processamento e flexibilidade cognitiva, além de pior desempenho em tarefas do Stroop que avaliam atenção dividida e controle de interferência. Embora as diferenças em memória de trabalho e fluência verbal tenham permanecido dentro dos intervalos normativos, análises estratificadas por idade revelaram prejuízos marcantes na memória de longo prazo no grupo com ASI entre 30 e 39 anos. Esses resultados sugerem que os déficits neurocognitivos no TPL não são universais, podendo refletir o impacto cumulativo do trauma precoce e da idade. Avaliações informadas pelo trauma e intervenções cognitivas personalizadas podem contribuir para uma caracterização mais precisa e para o desenvolvimento de estratégias terapêuticas adaptadas nesse subgrupo de alto risco. [ABSTRACT FROM AUTHOR] |
| Copyright of Panamerican Journal of Neuropsychology / Cuadernos de Neuropsicología is the property of Cuadernos de Neuropsicologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
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| Header | DbId: lth DbLabel: MedicLatina An: 196041967 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: NEUROCOGNITIVE HETEROGENEITY IN BORDERLINE PERSONALITY DISORDER: THE ROLE OF CHILDHOOD SEXUAL ABUSE. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: HETEROGENEIDAD NEUROCOGNITIVA EN EL TRASTORNO LÍMITE DE LA PERSONALIDAD: EL PAPEL DEL ABUSO SEXUAL INFANTIL.<br />HETEROGENEIDADE NEUROCOGNITIVA NO TRANSTORNO DE PERSONALIDADE LIMÍTROFE: O PAPEL DO ABUSO SEXUAL INFANTIL. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Cabrera%2C+Horus+Laffite%22">Cabrera, Horus Laffite</searchLink><relatesTo>1,2</relatesTo><i> hlafcab@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Rodríguez-Otero%2C+Fernando%22">Rodríguez-Otero, Fernando</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Alonso-Sosa%2C+Raquel%22">Alonso-Sosa, Raquel</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Martínez-Huidobro%2C+María+F%2E%22">Martínez-Huidobro, María F.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Hernández-Fleta%2C+José+L%2E%22">Hernández-Fleta, José L.</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Díaz-Garrido%2C+Juan+Antonio%22">Díaz-Garrido, Juan Antonio</searchLink><relatesTo>1,2,3</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Panamerican+Journal+of+Neuropsychology+%2F+Cuadernos+de+Neuropsicología%22">Panamerican Journal of Neuropsychology / Cuadernos de Neuropsicología</searchLink>. may-ago2026, Vol. 20 Issue 2, p93-111. 19p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Child+sexual+abuse%22">Child sexual abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Borderline+personality+disorder%22">Borderline personality disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+flexibility%22">Cognitive flexibility</searchLink><br /><searchLink fieldCode="DE" term="%22Neurobehavioral+disorders%22">Neurobehavioral disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Memory+disorders%22">Memory disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Attention-deficit+hyperactivity+disorder%22">Attention-deficit hyperactivity disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Trauma-informed+care%22">Trauma-informed care</searchLink><br /><searchLink fieldCode="DE" term="%22Impulsive+personality%22">Impulsive personality</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Childhood sexual abuse (CSA) is strongly associated with borderline personality disorder (BPD). This cross-sectional study investigated clinical and neurocognitive differences in 193 women aged 20 to 39 years diagnosed with BPD, comparing those with a history of CSA (n = 78) and those without (n = 115). Participants completed standardized psychometric and neuropsychological assessments focused on impulsivity, core BPD symptoms, and cognitive functioning. Women with CSA showed greater clinical severity, including higher rates of self-harm, suicide attempts, dissociative and psychotic symptoms, along with elevated impulsivity and attention-deficit/hyperactivity disorder (ADHD)–related traits. Neuropsychological testing revealed significant deficits in attention, processing speed, and cognitive flexibility, along with lower performance on Stroop tasks assessing divided attention and interference control. While working memory and verbal fluency differences remained within normative ranges, age-stratified analysis revealed marked long-term memory impairments in the CSA group aged 30–39. These results suggest that neurocognitive deficits in BPD are not universal but may reflect the cumulative impact of early trauma and age. Trauma-informed assessment and tailored cognitive interventions may support more accurate profiling and inform tailored therapeutic strategies in this highrisk subgroup. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: El abuso sexual infantil (ASI) se asocia de forma consistente con el trastorno límite de la personalidad (TLP). Este estudio transversal examinó las diferencias clínicas y neurocognitivas en 193 mujeres de entre 20 y 39 años con diagnóstico de TLP, comparando aquellas con antecedentes de ASI (n = 78) y aquellas sin tales antecedentes (n = 115). Las participantes completaron evaluaciones psicométricas y neuropsicológicas estandarizadas centradas en impulsividad, sintomatología propia del TLP y funcionamiento cognitivo. Las mujeres con ASI mostraron una mayor gravedad clínica, incluyendo tasas más elevadas de autolesiones, intentos de suicidio, síntomas disociativos y psicóticos, así como una mayor impulsividad y presencia de rasgos relacionados con el trastorno por déficit de atención con hiperactividad (TDAH). A nivel neurocognitivo, se observaron déficits significativos en atención, velocidad de procesamiento y flexibilidad cognitiva, así como un rendimiento reducido en tareas que requerían atención dividida y control de interferencias. Si bien las diferencias en memoria de trabajo y fluidez verbal se mantuvieron dentro de los rangos normativos, los análisis estratificados por edad revelaron alteraciones marcadas en la memoria a largo plazo en el grupo con ASI entre los 30 y 39 años. Estos hallazgos sugieren que los déficits neurocognitivos en el TLP no son universales, sino que podrían reflejar el impacto acumulativo del trauma temprano y la vulnerabilidad asociada a la edad. La evaluación informada por el trauma y el diseño de intervenciones cognitivas personalizadas podrían contribuir a mejorar la precisión diagnóstica y la eficacia terapéutica en este subgrupo de alto riesgo. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Portuguese) Group: Ab Data: O abuso sexual infantil (ASI) está fortemente associado ao transtorno de personalidade limítrofe (TPL). Este estudo transversal investigou diferenças clínicas e neurocognitivas em 193 mulheres, com idades entre 20 e 39 anos, diagnosticadas com TPL, comparando aquelas com histórico de ASI (n = 78) e aquelas sem esse antecedente (n = 115). As participantes realizaram avaliações psicométricas e neuropsicológicas padronizadas, com foco na impulsividade, nos sintomas centrais do TPL e no funcionamento cognitivo. As mulheres com ASI apresentaram maior gravidade clínica, incluindo taxas mais elevadas de autolesão, tentativas de suicídio, sintomas dissociativos e psicóticos, bem como maior impulsividade e presença de características associadas ao transtorno de déficit de atenção/hiperatividade (TDAH). A avaliação neuropsicológica revelou déficits significativos em atenção, velocidade de processamento e flexibilidade cognitiva, além de pior desempenho em tarefas do Stroop que avaliam atenção dividida e controle de interferência. Embora as diferenças em memória de trabalho e fluência verbal tenham permanecido dentro dos intervalos normativos, análises estratificadas por idade revelaram prejuízos marcantes na memória de longo prazo no grupo com ASI entre 30 e 39 anos. Esses resultados sugerem que os déficits neurocognitivos no TPL não são universais, podendo refletir o impacto cumulativo do trauma precoce e da idade. Avaliações informadas pelo trauma e intervenções cognitivas personalizadas podem contribuir para uma caracterização mais precisa e para o desenvolvimento de estratégias terapêuticas adaptadas nesse subgrupo de alto risco. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Panamerican Journal of Neuropsychology / Cuadernos de Neuropsicología is the property of Cuadernos de Neuropsicologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.7714/CNPS/20.2.206 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 19 StartPage: 93 Subjects: – SubjectFull: Child sexual abuse Type: general – SubjectFull: Borderline personality disorder Type: general – SubjectFull: Cognitive flexibility Type: general – SubjectFull: Neurobehavioral disorders Type: general – SubjectFull: Memory disorders Type: general – SubjectFull: Attention-deficit hyperactivity disorder Type: general – SubjectFull: Trauma-informed care Type: general – SubjectFull: Impulsive personality Type: general Titles: – TitleFull: NEUROCOGNITIVE HETEROGENEITY IN BORDERLINE PERSONALITY DISORDER: THE ROLE OF CHILDHOOD SEXUAL ABUSE. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cabrera, Horus Laffite – PersonEntity: Name: NameFull: Rodríguez-Otero, Fernando – PersonEntity: Name: NameFull: Alonso-Sosa, Raquel – PersonEntity: Name: NameFull: Martínez-Huidobro, María F. – PersonEntity: Name: NameFull: Hernández-Fleta, José L. – PersonEntity: Name: NameFull: Díaz-Garrido, Juan Antonio IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: may-ago2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 07184123 Numbering: – Type: volume Value: 20 – Type: issue Value: 2 Titles: – TitleFull: Panamerican Journal of Neuropsychology / Cuadernos de Neuropsicología Type: main |
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