Síndrome de hipersensibilidad por uso de Trimetoprim/sulfametoxazol. Reporte de un caso.
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| Title: | Síndrome de hipersensibilidad por uso de Trimetoprim/sulfametoxazol. Reporte de un caso. |
|---|---|
| Alternate Title: | Trimethoprim/sulfamethoxazole hypersensibility syndrome. A Case Report. |
| Authors: | Ticse Aguirre, Ray1 rayticse@yahoo.com, Huayanay Falconi, Leandro2, Malaga Rodriguez, Germán2, Ferrufino Llach, Juan Carlos3, Ramos Aguilar, Cesar4 |
| Source: | Revista Medica Herediana. abr-jun2006, Vol. 17 Issue 2, p109-114. 6p. |
| Subjects: | LEUCOCYTOSIS, LEUKOCYTE disorders, EDEMA, SULFONAMIDES, AMIDES |
| Abstract (English): | 27 year old male, admitted to the emergency room with a 3 week history of pruriginous skin rash that began on trunk and then appeared on arms and legs. A week latter patient developed dyspnea and non productive cough. One weak prior to admission patient had desquamative skin lesions, dyspnea at rest and edema on both legs. He had a past medical history of Non-Hodgkin's B cell lymphoma and Pneumocystis jiroveci, pneumonitis treated with Trimethoprim/sulfamethoxazole 2 month prior to admission. Laboratory test showed leukocytosis with eosinophilia, cholestatic liver injury and hypoxemia. On chest X-ray the patient had an interstitial pneumonitis. Skin biopsy was positive for drug allergy. Skin lesions, hematological and systemic compromise defined the diagnosis of Trimethoprim/sulfamethoxazole hypersensibility syndrome. Drug was discontinued and corticosteroid treatment started. Case is discussed and literature was reviewed. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Paciente varón de 27 años que fue admitido por el servicio de emergencia del Hospital Nacional Cayetano Heredia con un tiempo de enfermedad de tres semanas, que inició con rash dérmico pruriginoso en tronco, luego en extremidades. Luego de una semana presentó disnea y tos no productiva. Una semana antes del ingreso presentó descamación de piel, disnea al reposo, y edema en miembros inferiores. Como antecedente dos meses antes se le diagnosticó Linfoma no Hodgkin Células B y neumonitis por Pneumocystis jiroveci por lo que recibió trimetoprim/sulfametoxazol. Los examenes de laboratorio mostraron leucocitosis con eosinofilia, compromiso hepático con patrón colestásico e hipoxemia. La radiografía de tórax mostró neumonitis intersticial. La biopsia de piel mostró reacción alérgica a medicamentos. La erupción cutánea, el compromiso hematológico y sistémico definieron el diagnóstico de síndrome de hipersensiblidad a trimetoprim/sulfametoxazol. Se suspendió éste fármaco e inició tratamiento con corticoides. Se discute el caso y se revisa la literatura. [ABSTRACT FROM AUTHOR] |
| Copyright of Revista Medica Herediana is the property of Universidad Peruana Cayetano Heredia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 22321888 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Síndrome de hipersensibilidad por uso de Trimetoprim/sulfametoxazol. Reporte de un caso. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Trimethoprim/sulfamethoxazole hypersensibility syndrome. A Case Report. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Ticse+Aguirre%2C+Ray%22">Ticse Aguirre, Ray</searchLink><relatesTo>1</relatesTo><i> rayticse@yahoo.com</i><br /><searchLink fieldCode="AR" term="%22Huayanay+Falconi%2C+Leandro%22">Huayanay Falconi, Leandro</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Malaga+Rodriguez%2C+Germán%22">Malaga Rodriguez, Germán</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Ferrufino+Llach%2C+Juan+Carlos%22">Ferrufino Llach, Juan Carlos</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Ramos+Aguilar%2C+Cesar%22">Ramos Aguilar, Cesar</searchLink><relatesTo>4</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Revista+Medica+Herediana%22">Revista Medica Herediana</searchLink>. abr-jun2006, Vol. 17 Issue 2, p109-114. 6p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22LEUCOCYTOSIS%22">LEUCOCYTOSIS</searchLink><br /><searchLink fieldCode="DE" term="%22LEUKOCYTE+disorders%22">LEUKOCYTE disorders</searchLink><br /><searchLink fieldCode="DE" term="%22EDEMA%22">EDEMA</searchLink><br /><searchLink fieldCode="DE" term="%22SULFONAMIDES%22">SULFONAMIDES</searchLink><br /><searchLink fieldCode="DE" term="%22AMIDES%22">AMIDES</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: 27 year old male, admitted to the emergency room with a 3 week history of pruriginous skin rash that began on trunk and then appeared on arms and legs. A week latter patient developed dyspnea and non productive cough. One weak prior to admission patient had desquamative skin lesions, dyspnea at rest and edema on both legs. He had a past medical history of Non-Hodgkin's B cell lymphoma and Pneumocystis jiroveci, pneumonitis treated with Trimethoprim/sulfamethoxazole 2 month prior to admission. Laboratory test showed leukocytosis with eosinophilia, cholestatic liver injury and hypoxemia. On chest X-ray the patient had an interstitial pneumonitis. Skin biopsy was positive for drug allergy. Skin lesions, hematological and systemic compromise defined the diagnosis of Trimethoprim/sulfamethoxazole hypersensibility syndrome. Drug was discontinued and corticosteroid treatment started. Case is discussed and literature was reviewed. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Paciente varón de 27 años que fue admitido por el servicio de emergencia del Hospital Nacional Cayetano Heredia con un tiempo de enfermedad de tres semanas, que inició con rash dérmico pruriginoso en tronco, luego en extremidades. Luego de una semana presentó disnea y tos no productiva. Una semana antes del ingreso presentó descamación de piel, disnea al reposo, y edema en miembros inferiores. Como antecedente dos meses antes se le diagnosticó Linfoma no Hodgkin Células B y neumonitis por Pneumocystis jiroveci por lo que recibió trimetoprim/sulfametoxazol. Los examenes de laboratorio mostraron leucocitosis con eosinofilia, compromiso hepático con patrón colestásico e hipoxemia. La radiografía de tórax mostró neumonitis intersticial. La biopsia de piel mostró reacción alérgica a medicamentos. La erupción cutánea, el compromiso hematológico y sistémico definieron el diagnóstico de síndrome de hipersensiblidad a trimetoprim/sulfametoxazol. Se suspendió éste fármaco e inició tratamiento con corticoides. Se discute el caso y se revisa la literatura. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Revista Medica Herediana is the property of Universidad Peruana Cayetano Heredia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=22321888 |
| RecordInfo | BibRecord: BibEntity: Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 6 StartPage: 109 Subjects: – SubjectFull: LEUCOCYTOSIS Type: general – SubjectFull: LEUKOCYTE disorders Type: general – SubjectFull: EDEMA Type: general – SubjectFull: SULFONAMIDES Type: general – SubjectFull: AMIDES Type: general Titles: – TitleFull: Síndrome de hipersensibilidad por uso de Trimetoprim/sulfametoxazol. Reporte de un caso. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ticse Aguirre, Ray – PersonEntity: Name: NameFull: Huayanay Falconi, Leandro – PersonEntity: Name: NameFull: Malaga Rodriguez, Germán – PersonEntity: Name: NameFull: Ferrufino Llach, Juan Carlos – PersonEntity: Name: NameFull: Ramos Aguilar, Cesar IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: abr-jun2006 Type: published Y: 2006 Identifiers: – Type: issn-print Value: 1018130X Numbering: – Type: volume Value: 17 – Type: issue Value: 2 Titles: – TitleFull: Revista Medica Herediana Type: main |
| ResultId | 1 |
