Prevalencia de defectos del tubo neural en 248 352 nacimientos consecutivos.
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| Title: | Prevalencia de defectos del tubo neural en 248 352 nacimientos consecutivos. |
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| Authors: | Hernández-Herrera, Ricardo Jorge1 richdzher@hotmail.com, Alcalá-Galván, Luis Gerardo2, Flores-Santos, Roberto2 |
| Source: | Revista Medica del IMSS. mar/abr2008, Vol. 46 Issue 2, p201-204. 4p. 1 Chart. |
| Subjects: | NEURAL tube defects, ANENCEPHALY, SPINA bifida, ENCEPHALOCELE, DEVELOPING countries |
| Geographic Terms: | MEXICO |
| Abstract (English): | Background: neural tube defects are a scourge for the population in non developed countries. Objective: to evaluate the prevalence of neural tube defects at a Gynecology and Obstetric Hospital at Instituto Mexicano del Seguro Social. Methods: it was compared two 5 years periods: one before (1995-1999 and other after (2000-2004) a State Health Department program (Secretaría de Salud, Nuevo Léon) with 5 mg folic acid supplementation once a week to women in reproductive age. Results: we registered 248 352 consecutive deliveries in a 10 year period, and we observed 319 cases of neural tube defects, with a global rate of 12.84 per 10 000 deliveries. From 1995 to 1999, there were 132 360, with 212 neural tube defects (16.01 rate per 10 000 deliveries); the anencephaly was 6.49, spina bifida 8.23, and encephalocele 1.28. After it was established the folic acid program, during the following period 2000 to 2004, there were 115 992 deliveries, 108 with neural tube defects (9.31 rate per 10 000 newborns), with 41.8 % reduction (p < 0.001). Also decreased anencephaly rates: 28.3 % (non significant) and spina bifida 63.4 % (p < 0.001). Conclusions: the neural tube defects rate has been declining in last five years comparing with 5 years before 41 %, significantly more for spina bifida than anencephaly. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Introducción: los defectos del tubo neural son un problema de salud pública en países no desarrollados. Objetivo: evaluar la prevalencia de los defectos del tubo neural en una unidad de ginecoobstetricia del Instituto Mexicano del Seguro Social. Material y métodos: se compararon dos periodos: cinco años antes (1995-1999) y cinco años después (2000-2004) del inicio de la campaña de administración semanal de 5 mg de ácido fólico a las mujeres en edad reproductiva, realizada por la Secretaría de Salud de Nuevo León. Resultados: en 10 años ocurrieron 248 352 nacimientos y 319 casos de defectos del tubo neural, con una tasa global de 12.84 por cada 10 mil nacimientos. De 1995 a 1999 hubo 132 360 nacimientos y se registraron 212 con defectos del tubo neural, para una tasa por cada 10 mil nacimientos de 16.01, con una tasa de anencefalia de 6.49, de espina bífida de 8.23, y de encefalocele de 1.28. De 2000 a 2004, posterior a la campaña estatal de ácido fólico, se registraron 115 992 nacimientos, con 108 casos de defectos del tubo neural, para una tasa por cada 10 mil nacimientos de 9.31, lo que demuestra una reducción significativa de 41.8 % (p < 0.001), y una reducción en la tasa de anencefalia de 28.3 % (no significativa) y de espina bífida de 63.4 % (p < 0.001). Conclusiones: estos resultados sugieren que los defectos del tubo neural han disminuido en los últimos cinco años alrededor de 40 %, con mayor significancia para espina bífida que para anencefalia. [ABSTRACT FROM AUTHOR] |
| Copyright of Revista Medica del IMSS is the property of Direccion de Prestaciones Medicas - IMSS and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 35049023 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Prevalencia de defectos del tubo neural en 248 352 nacimientos consecutivos. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Hernández-Herrera%2C+Ricardo+Jorge%22">Hernández-Herrera, Ricardo Jorge</searchLink><relatesTo>1</relatesTo><i> richdzher@hotmail.com</i><br /><searchLink fieldCode="AR" term="%22Alcalá-Galván%2C+Luis+Gerardo%22">Alcalá-Galván, Luis Gerardo</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Flores-Santos%2C+Roberto%22">Flores-Santos, Roberto</searchLink><relatesTo>2</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Revista+Medica+del+IMSS%22">Revista Medica del IMSS</searchLink>. mar/abr2008, Vol. 46 Issue 2, p201-204. 4p. 1 Chart. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22NEURAL+tube+defects%22">NEURAL tube defects</searchLink><br /><searchLink fieldCode="DE" term="%22ANENCEPHALY%22">ANENCEPHALY</searchLink><br /><searchLink fieldCode="DE" term="%22SPINA+bifida%22">SPINA bifida</searchLink><br /><searchLink fieldCode="DE" term="%22ENCEPHALOCELE%22">ENCEPHALOCELE</searchLink><br /><searchLink fieldCode="DE" term="%22DEVELOPING+countries%22">DEVELOPING countries</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22MEXICO%22">MEXICO</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Background: neural tube defects are a scourge for the population in non developed countries. Objective: to evaluate the prevalence of neural tube defects at a Gynecology and Obstetric Hospital at Instituto Mexicano del Seguro Social. Methods: it was compared two 5 years periods: one before (1995-1999 and other after (2000-2004) a State Health Department program (Secretaría de Salud, Nuevo Léon) with 5 mg folic acid supplementation once a week to women in reproductive age. Results: we registered 248 352 consecutive deliveries in a 10 year period, and we observed 319 cases of neural tube defects, with a global rate of 12.84 per 10 000 deliveries. From 1995 to 1999, there were 132 360, with 212 neural tube defects (16.01 rate per 10 000 deliveries); the anencephaly was 6.49, spina bifida 8.23, and encephalocele 1.28. After it was established the folic acid program, during the following period 2000 to 2004, there were 115 992 deliveries, 108 with neural tube defects (9.31 rate per 10 000 newborns), with 41.8 % reduction (p < 0.001). Also decreased anencephaly rates: 28.3 % (non significant) and spina bifida 63.4 % (p < 0.001). Conclusions: the neural tube defects rate has been declining in last five years comparing with 5 years before 41 %, significantly more for spina bifida than anencephaly. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Introducción: los defectos del tubo neural son un problema de salud pública en países no desarrollados. Objetivo: evaluar la prevalencia de los defectos del tubo neural en una unidad de ginecoobstetricia del Instituto Mexicano del Seguro Social. Material y métodos: se compararon dos periodos: cinco años antes (1995-1999) y cinco años después (2000-2004) del inicio de la campaña de administración semanal de 5 mg de ácido fólico a las mujeres en edad reproductiva, realizada por la Secretaría de Salud de Nuevo León. Resultados: en 10 años ocurrieron 248 352 nacimientos y 319 casos de defectos del tubo neural, con una tasa global de 12.84 por cada 10 mil nacimientos. De 1995 a 1999 hubo 132 360 nacimientos y se registraron 212 con defectos del tubo neural, para una tasa por cada 10 mil nacimientos de 16.01, con una tasa de anencefalia de 6.49, de espina bífida de 8.23, y de encefalocele de 1.28. De 2000 a 2004, posterior a la campaña estatal de ácido fólico, se registraron 115 992 nacimientos, con 108 casos de defectos del tubo neural, para una tasa por cada 10 mil nacimientos de 9.31, lo que demuestra una reducción significativa de 41.8 % (p < 0.001), y una reducción en la tasa de anencefalia de 28.3 % (no significativa) y de espina bífida de 63.4 % (p < 0.001). Conclusiones: estos resultados sugieren que los defectos del tubo neural han disminuido en los últimos cinco años alrededor de 40 %, con mayor significancia para espina bífida que para anencefalia. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Revista Medica del IMSS is the property of Direccion de Prestaciones Medicas - IMSS and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 4 StartPage: 201 Subjects: – SubjectFull: NEURAL tube defects Type: general – SubjectFull: ANENCEPHALY Type: general – SubjectFull: SPINA bifida Type: general – SubjectFull: ENCEPHALOCELE Type: general – SubjectFull: DEVELOPING countries Type: general – SubjectFull: MEXICO Type: general Titles: – TitleFull: Prevalencia de defectos del tubo neural en 248 352 nacimientos consecutivos. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hernández-Herrera, Ricardo Jorge – PersonEntity: Name: NameFull: Alcalá-Galván, Luis Gerardo – PersonEntity: Name: NameFull: Flores-Santos, Roberto IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: mar/abr2008 Type: published Y: 2008 Identifiers: – Type: issn-print Value: 04435117 Numbering: – Type: volume Value: 46 – Type: issue Value: 2 Titles: – TitleFull: Revista Medica del IMSS Type: main |
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