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Antitrombina-III en la preeclampsia-eclampsia. Estudio piloto.

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Title: Antitrombina-III en la preeclampsia-eclampsia. Estudio piloto.
Authors: Verduzco Rodriguez, DR. Leonardo, Gonzalez Puebla, DR. Enrique, Lopez Ariza, DR. Benjamin, Manffrini Madrid, DR. Francisco
Source: Ginecología y Obstetricia de México. ago1998, Vol. 66 Issue 8, p343. 7p. 4 Charts.
Abstract: RESUMEN Se estudiaron los niveles funcionales de antitrombina-III en los siguientes grupos:A. mujeres sanas no embarazadas: 11 casos.B. mujeres sanas embarazadas en el 3er trimestre sin complicaciones: 13 casos.C. mujeres con preeclampsia leve a severa: 6 casos.D. mujeres con eclampsia o síndrome de HELLP: 5 casos.Los niveles plasmáticos de antitrombina-III disminuidos en pacientes con diversos grados de toxemia parecen deberse a coagulación intravascular de bajo grado en preeclampsia y de alto grado en eclampsia y HELLP como principal causa. Debería investigarse su utilidad como prueba de tamizaje para etapas preclínicas y en pruebas de detección temprana y como un indicador de la gravedad de la enfermedad. Estos resultados preliminares justifican la realización de estudios prospectivos con mayor número de casos.SUMMARY The functional levels of AT-III were determined to the following four groups:A. Eleven healthy non pregnant womenB. Thirteen healthy pregnant women (third trimester).C. Six preeclamptic patients.D. Five patients with eclampsia and/or HELLP syndrome.A different grade of DIC may explain the low activity of AT-III in preeclampsia and a more severe coagulation disorder in eclampsia and HELLP syndrome.Our preliminary results encourage other prospective studies including larger populations to determine its usefulness as early diagnostic test and severity marker of the disease. [ABSTRACT FROM AUTHOR]
Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Antitrombina-III en la preeclampsia-eclampsia. Estudio piloto.
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  Data: <searchLink fieldCode="AR" term="%22Verduzco+Rodriguez%2C+DR%2E+Leonardo%22">Verduzco Rodriguez, DR. Leonardo</searchLink><br /><searchLink fieldCode="AR" term="%22Gonzalez+Puebla%2C+DR%2E+Enrique%22">Gonzalez Puebla, DR. Enrique</searchLink><br /><searchLink fieldCode="AR" term="%22Lopez+Ariza%2C+DR%2E+Benjamin%22">Lopez Ariza, DR. Benjamin</searchLink><br /><searchLink fieldCode="AR" term="%22Manffrini+Madrid%2C+DR%2E+Francisco%22">Manffrini Madrid, DR. Francisco</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Ginecología+y+Obstetricia+de+México%22">Ginecología y Obstetricia de México</searchLink>. ago1998, Vol. 66 Issue 8, p343. 7p. 4 Charts.
– Name: Abstract
  Label: Abstract
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  Data: RESUMEN Se estudiaron los niveles funcionales de antitrombina-III en los siguientes grupos:A. mujeres sanas no embarazadas: 11 casos.B. mujeres sanas embarazadas en el 3er trimestre sin complicaciones: 13 casos.C. mujeres con preeclampsia leve a severa: 6 casos.D. mujeres con eclampsia o síndrome de HELLP: 5 casos.Los niveles plasmáticos de antitrombina-III disminuidos en pacientes con diversos grados de toxemia parecen deberse a coagulación intravascular de bajo grado en preeclampsia y de alto grado en eclampsia y HELLP como principal causa. Debería investigarse su utilidad como prueba de tamizaje para etapas preclínicas y en pruebas de detección temprana y como un indicador de la gravedad de la enfermedad. Estos resultados preliminares justifican la realización de estudios prospectivos con mayor número de casos.SUMMARY The functional levels of AT-III were determined to the following four groups:A. Eleven healthy non pregnant womenB. Thirteen healthy pregnant women (third trimester).C. Six preeclamptic patients.D. Five patients with eclampsia and/or HELLP syndrome.A different grade of DIC may explain the low activity of AT-III in preeclampsia and a more severe coagulation disorder in eclampsia and HELLP syndrome.Our preliminary results encourage other prospective studies including larger populations to determine its usefulness as early diagnostic test and severity marker of the disease. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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