Mecanismos de acción electrofisiológicos de la terapia electroconvulsiva.
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| Title: | Mecanismos de acción electrofisiológicos de la terapia electroconvulsiva. |
|---|---|
| Alternate Title: | Electrophysiological mechanisms of action of electroconvulsive therapy. |
| Authors: | Sánchez, R.1 39639rsg@comb.cat, Alcoverro, Ò.2, Pagerols, J.1, Rojo, J. E.2 |
| Source: | Actas Espanolas de Psiquiatria. nov2009, Vol. 37 Issue 6, p343-351. 9p. 1 Chart, 1 Graph. |
| Subjects: | ELECTROCONVULSIVE therapy, ELECTROPHYSIOLOGY, NEUROBIOLOGY, MENTAL illness treatment, PSYCHOTHERAPY, EDUCATION |
| Abstract (English): | In spite of the guidelines and consensus on its indications and application, electroconvulsive therapy (ECT) continues to be one of the therapeutic procedures with less knowledge on its mechanism of action. It is interesting to evaluate the way in which the factors that modulate the convulsant activity can be modified by this therapy and its relation with the therapeutic effect. The aim of the present article is to review, in the context of neurobiological theories, the bibliography regarding the electrophysiological mechanisms of action of ECT, mainly the anticonvulsant hypothesis. Having better knowledge about these mechanisms can achieve an improvement in the clinical practice and provide a starting point to search for alternative treatments based on the same physical bases. After doing a study of all the papers and reference books, those works which, according to their methodology and design, provide relevant scientific information with regard to the principal topic of this review and that have been published between 1993 and 2007 were selected. In order to provide better consistency to the text, a series of articles prior to 1993 that were considered important within the setting studied have been included, since they establish the theoretical bases of ECT and have been frequently mentioned after their sublication. The scientific evidence obtained is systematized into three sections: basic concepts, neurophysiological hypotheses and electrophysiological findings. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Pese a la elaboración de guías y consensos sobre sus indicaciones y aplicación, la terapia electroconvulsiva (TEC) sigue siendo uno de los procedimientos terapéuticos con menor certeza en su mecanismo de acción. Es interesante evaluar la manera en la que los factores que modulan la actividad convulsiva pueden ser modificados por esta terapia y su relación con el efecto terapéutico. El objetivo del presente artículo es revisar, en el contexto de las teorías neurobiológicas, la bibliografía existente sobre los mecanismos de acción electrofisiológicos de la TEC, principalmente la hipótesis anticonvulsiva. El mayor conocimiento sobre dichos mecanismos, puede conseguir una optimización en la práctica asistencial, así como un punto de partida para buscar tratamientos alternativos basados en las mismas bases físicas. Entre todos los artículos y libros de texto, se han seleccionado aquellos trabajos que, por su metodología y diseño, aportan datos científicamente relevantes respecto al tema principal de esta revisión y que hayan sido publicados entre 1993 y 2007. A fin de aportar mayor consistencia al texto, también se han incluido una serie de artículos, previos a 1993, considerados importantes en el ámbito que se trata, puesto que establecen las bases teóricas de la TEC y han sido citados con frecuencia tras su publicación. Las evidencias científicas obtenidas se sistematizan en tres apartados: conceptos básicos, hipótesis neurofisiológicas y hallazgos electrofisiológicos. [ABSTRACT FROM AUTHOR] |
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| Database: | MedicLatina |
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